{"id":47310,"date":"2003-10-16T00:00:00","date_gmt":"2003-10-16T05:00:00","guid":{"rendered":"https:\/\/www.unmc.edu\/newsroom\/2003\/10\/16\/unmcs-total-research-grants-reach-record-62-million-2\/"},"modified":"2022-08-29T10:43:23","modified_gmt":"2022-08-29T15:43:23","slug":"unmcs-total-research-grants-reach-record-62-million-2","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/newsroom\/2003\/10\/16\/unmcs-total-research-grants-reach-record-62-million-2\/","title":{"rendered":"UNMC&#8217;s total research grants reach record $62 million"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\"><p>The University of Nebraska Medical Center has broken its record for<\/p>\n<p>total research grants in a single quarter by bringing in $26 million during<\/p>\n<p>July, August and September. The record quarter brings UNMCs total grant<\/p>\n<p>funding to $62 million.<\/p>\n<p>University officials are particularly pleased with the increase because<\/p>\n<p>the national research funding pool was sharply reduced due to a tight economy<\/p>\n<p>and the diversion of significant funds from basic research to biosecurity-related<\/p>\n<p>projects.<\/p>\n<p>While the economy was slumping and state funding was going down, we<\/p>\n<p>still managed to continue our momentum, said Thomas Rosenquist, Ph.D.,<\/p>\n<p>UNMC vice chancellor for research. Lots of money that we went after in<\/p>\n<p>the past is now earmarked for biosecurity and other areas that are currently<\/p>\n<p>not accessible to us.<\/p>\n<p>Yet, we received some significant grant awards early in the new fiscal<\/p>\n<p>year that helped to surpass the previous single quarter record and propel<\/p>\n<p>us forward to date.<\/p>\n<p>Dr. Rosenquist said UNMCs impressive start for the 2003-04 fiscal year<\/p>\n<p>featured grant awards of more than $20.5 million in one week in September<\/p>\n<p>thanks to the two largest grants in UNMC history.<\/p>\n<p>The largest single award was a five-year grant totaling more than $10.6<\/p>\n<p>million. Awarded to study genes in neurosensory systems, the grant was<\/p>\n<p>funded by the Centers of Biomedical Research Excellence (CoBRE) program,<\/p>\n<p>which is supported by the NIH. Through the grant support, UNMC will form<\/p>\n<p>a research center to study the relationship between neurosensory conditions<\/p>\n<p>and specific genes or gene pathways, including disorders of vision and<\/p>\n<p>hearing, as well as touch and balance. Shelley Smith, Ph.D., director of<\/p>\n<p>the UNMC Center for Molecular Genetics, is the principal investigator for<\/p>\n<p>the grant and will direct the NIH-designated Nebraska Center for Molecular<\/p>\n<p>Biology of Neurosensory Systems.<\/p>\n<p>A five-year grant totaling almost $9.9 million is the second largest<\/p>\n<p>grant ever received by UNMC.<\/p>\n<p>The grant establishes an NIH-designated Nebraska Center for Cellular<\/p>\n<p>Signaling at UNMC to further the understanding of cell signaling  the<\/p>\n<p>biochemical response of cells to their environment  in relation to a variety<\/p>\n<p>of cancers. Margaret Wheelock, Ph.D., professor of oral biology, UNMC College<\/p>\n<p>of Dentistry, is principal investigator and director of the new center.<\/p>\n<p>UNMC received $15 million in total research grants for the fourth quarter<\/p>\n<p>of the 2002-03 fiscal year (April, May, June 2003), ending the year with<\/p>\n<p>a total of $55.8 million. Thirty-five investigators received grants worth<\/p>\n<p>$100,000 or more in the fourth quarter. Among the highlights:<\/p>\n<p>Jeffrey Payne, D.D.S., assistant dean for research, UNMC College of<\/p>\n<p>Dentistry, received $537,094 from the NIH to conduct a two-year clinical<\/p>\n<p>trial on the use of a low dose of doxycycline as an inexpensive, safe means<\/p>\n<p>to reduce loss of bone density in the mouth, hip and spine of postmenopausal<\/p>\n<p>women.&nbsp; These women will have periodontitis (oral bone loss), which<\/p>\n<p>afflicts at least 35 percent of U.S. adults and is the primary cause of<\/p>\n<p>adult tooth loss, and will be at risk for osteoporosis.&nbsp; Osteoporosis<\/p>\n<p>is associated with an increased incidence of vertebrae, wrist and hip fractures<\/p>\n<p>and tooth loss.<\/p>\n<p>Jialin Zheng, M.D., associate professor in the Center for Neurovirology<\/p>\n<p>and Neurodegenerative Disorders, department of pathology\/microbiology,<\/p>\n<p>received $257,250 to study HIV-associated dementia (HAD). HIV affects approximately<\/p>\n<p>40 million individuals worldwide. In its late stages, approximately 20<\/p>\n<p>percent of infected adults and 50 percent of infected children suffer from<\/p>\n<p>HAD and can suffer a severe loss of memory and poor to no retention. Scientific<\/p>\n<p>studies have established that macrophages, an important part of the immune<\/p>\n<p>system that aids the fight against unwanted invaders and are a target of<\/p>\n<p>the HIV virus, talk to other macrophages and other cells, including neurons,<\/p>\n<p>through chemical signaling.&nbsp; The research team seeks to identify what<\/p>\n<p>these chemical signals mean and how these signals from HIV-infected macrophages<\/p>\n<p>affect the neurons in the brain.<\/p>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>The University of Nebraska Medical Center has broken its record for total research grants in a single quarter by bringing in $26 million during July, August and September. The record quarter brings UNMCs total grant funding to $62 million. University officials are particularly pleased with the increase because the national research funding pool was sharply [&hellip;]<\/p>\n","protected":false},"author":79,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-47310","post","type-post","status-publish","format-standard","hentry","category-uncategorized","department-press-release"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ 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