{"id":47513,"date":"1998-10-21T00:00:00","date_gmt":"1998-10-21T05:00:00","guid":{"rendered":"https:\/\/www.unmc.edu\/newsroom\/1998\/10\/21\/vitamin-c-may-inhibit-development-of-stomach-and-esophagealcancers\/"},"modified":"2022-08-29T10:59:52","modified_gmt":"2022-08-29T15:59:52","slug":"vitamin-c-may-inhibit-development-of-stomach-and-esophagealcancers","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/newsroom\/1998\/10\/21\/vitamin-c-may-inhibit-development-of-stomach-and-esophagealcancers\/","title":{"rendered":"Vitamin C May Inhibit Development of Stomach and Esophageal\n\nCancers"},"content":{"rendered":"

<\/FONT><\/B><\/p>\n

 Taking vitamin C with each meal may help prevent stomach and esophageal<\/p>\n

cancer, according to a study<\/p>\n


 published this fall in the journal Nutrition and Cancer. The<\/p>\n

study was headed by Sidney Mirvish, Ph.D., a researcher at the Eppley Institute<\/p>\n

for Research in Cancer and Allied Diseases at the University of Nebraska<\/p>\n

Medical Center. Collaborators included Ann Grandjean, Ph.D., and Kristen<\/p>\n

Reimers, both of the Center for Human Nutrition in Omaha.<\/p>\n

 Findings from the study indicate that taking 80 to 100 mg of vitamin<\/p>\n

C three times a day with each meal significantly reduces the formation<\/p>\n

of chemicals called nitrosamines. Many cancer researchers believe nitrosamines<\/p>\n

cause some cancers, such as stomach and esophageal cancers. Currently,<\/p>\n

the recommended allowance of vitamin C is 60 mg per day.<\/p>\n

 Nitrosamines can form in the body when components of certain foods<\/p>\n

react with the nitrite in stomach juices. This nitrite is mostly produced<\/p>\n

in the body from nitrate found in food and drinking water.<\/p>\n

 Study participants were given a nitrate salt one hour before each<\/p>\n

meal and an amino acid called proline with each meal to induce formation<\/p>\n

of a harmless nitrosamine. Researchers found that when a 120-mg dose of<\/p>\n

vitamin C was given with the meal, formation of the nitrosamine was blocked.<\/p>\n

Because the average amount of nitrate a person normally consumes is less<\/p>\n

than the amount given in the experiment, it was estimated that taking 80<\/p>\n

to 100 mg with each meal will effectively reduce the formation of nitrosamines.<\/p>\n

 A study by Dr. Mirvishs group in 1995 found that vitamin C will<\/p>\n

produce this action only when it is taken from two hours before to one<\/p>\n

hour after a meal.<\/p>\n

The nitrosamine-reducing effect is one of several ways vitamin C can<\/p>\n

help you maintain a healthier lifestyle, said Dr. Mirvish. Vitamin C<\/p>\n

acts here by removing nitrite from the stomach for at least one hour after<\/p>\n

the vitamin is taken.<\/p>\n

 Dr. Mirvish and his group first demonstrated the cancer-preventive<\/p>\n

capabilities of vitamin C in 1972, in<\/p>\n


laboratory experiments that showed the vitamin effectively prevented<\/p>\n

nitrosamines from forming. This study was supported by grants from the<\/p>\n

Nebraska Department of Health, the National Cancer Institute and the American<\/p>\n

Cancer Society.<\/p>\n

 The Eppley Institute is a part of the UNMC Eppley Cancer Center,<\/p>\n

which is one of more than 50 National Cancer Institute-designated cancer<\/p>\n

centers. Of the $34 million in research grants awarded to UNMC in 1996-1997,<\/p>\n

Cancer Center researchers generated more than $20 million.<\/p>\n

 UNMC is the only public academic health science center in the<\/p>\n

state. Through its commitment to research, education and patient care,<\/p>\n

UNMC has established itself as one of the countrys leading centers for<\/p>\n

cancer research and treatment and solid organ transplantation. In addition,<\/p>\n

UNMCs educational programs are responsible for training more health professionals<\/p>\n

practicing in Nebraska than any other institution.<\/p>\n


 <\/p>\n


 <\/p>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"

 Taking vitamin C with each meal may help prevent stomach and esophageal cancer, according to a study  published this fall in the journal Nutrition and Cancer. The study was headed by Sidney Mirvish, Ph.D., a researcher at the Eppley Institute for Research in Cancer and Allied Diseases at the University of Nebraska Medical Center. Collaborators […]<\/p>\n","protected":false},"author":79,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-47513","post","type-post","status-publish","format-standard","hentry","category-uncategorized","department-press-release"],"yoast_head":"\nVitamin C May Inhibit Development of Stomach and Esophageal Cancers<\/title>\n<meta name=\"description\" content=\" Taking vitamin C with each meal may help prevent stomach and esophageal cancer, according to a study 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