{"id":47561,"date":"2003-09-15T00:00:00","date_gmt":"2003-09-15T05:00:00","guid":{"rendered":"https:\/\/www.unmc.edu\/newsroom\/2003\/09\/15\/unmc-receives-10-6-million-grant-from-nih-to-studygenes-in-neurosensory-systems\/"},"modified":"2022-08-29T10:43:37","modified_gmt":"2022-08-29T15:43:37","slug":"unmc-receives-10-6-million-grant-from-nih-to-studygenes-in-neurosensory-systems","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/newsroom\/2003\/09\/15\/unmc-receives-10-6-million-grant-from-nih-to-studygenes-in-neurosensory-systems\/","title":{"rendered":"UNMC receives $10.6 million grant from NIH to study\n\ngenes in neurosensory systems"},"content":{"rendered":"

The University of Nebraska Medical Center learned today that it has<\/p>\n

been awarded a five-year grant totaling more than $10.6 million from the<\/p>\n

National Institutes of Health (NIH) to study genes in neurosensory systems.<\/p>\n

The grant the largest ever received by UNMC was funded through the<\/p>\n

Centers of Biomedical Research Excellence (CoBRE) program, which is supported<\/p>\n

by the NIH.<\/p>\n

We are tremendously pleased that we have been awarded this grant,<\/p>\n

UNMC Chancellor Harold M. Maurer, M.D. said. The grant went through an<\/p>\n

extremely competitive process by the National Institutes of Health and<\/p>\n

was selected because of its promise to humanity. I could not be more pleased.<\/p>\n

Through the grant support, UNMC will form a research center to study<\/p>\n

the relationships between neurosensory conditions and specific genes or<\/p>\n

gene pathways, including disorders of vision and hearing, as well as touch<\/p>\n

and balance.<\/p>\n

Shelley Smith, Ph.D, director of the UNMC Center for Molecular Genetics,<\/p>\n

is the principal investigator for the grant and will direct the Nebraska<\/p>\n

Center for Molecular Biology of Neurosensory Systems.<\/p>\n

Dr. Smith said the COBRE grant for the Nebraska Center for Molecular<\/p>\n

Biology of Neurosensory Systems will involve four research projects at<\/p>\n

three different institutions UNMC, Creighton University and Boys Town<\/p>\n

National Research Hospital. Three core facilities all established through<\/p>\n

the Center for Human Molecular Genetics at UNMC are part of the COBRE<\/p>\n

grant, as well, Dr. Smith said.<\/p>\n

In one research project, a team of UNMC researchers will study the genes<\/p>\n

in the auditory system that respond to alcohol exposure in fetal alcohol<\/p>\n

syndrome. Other studies will involve the effect of growth factors on the<\/p>\n

development of nerve connections to the skin, genetic factors that protect<\/p>\n

against viral infections of the nervous system, and the development and<\/p>\n

maintenance of balance in aging adults.<\/p>\n

Because of the size of this grant, the proposal underwent enormous<\/p>\n

review, said Thomas Rosenquist, Ph.D, vice chancellor for research at<\/p>\n

UNMC. These (CoBRE) grants are highly competitive because theyre so big<\/p>\n

and because theyre extraordinarily valuable to the state.<\/p>\n

U.S. Sen. Chuck Hagel said the award reflects the confidence placed<\/p>\n

in UNMC by the NIH.<\/p>\n

Todays announcement is testament to the world-class work that is taking<\/p>\n

place at UNMC, Hagel said. Nebraskans and this country greatly benefit<\/p>\n

from UNMCs cutting-edge work.<\/p>\n

U.S. Sen. Ben Nelson said it is no surprise that UNMC is recognized<\/p>\n

as a preeminent institution by its peers.<\/p>\n

NIH has recognized the cutting-edge work, the superiority of facilities<\/p>\n

and the leading minds at UNMC by awarding this important biomedical research<\/p>\n

grant, Nelson said. UNMC’s work in this field will bring about advancements<\/p>\n

in health technology, treatment options and new perspectives in addressing<\/p>\n

medical challenges.<\/p>\n

Congressman Lee Terry, who represents the Second District, in which<\/p>\n

UNMCs main campus resides, said the grant announcement is tremendous news<\/p>\n

for UNMC and all of Nebraska.<\/p>\n

We can be proud that UNMC has again been recognized for its ground-breaking<\/p>\n

research, which provides real returns to every resident of our state,<\/p>\n

Terry said. The fact that other local institutions — such as Creighton<\/p>\n

University and Boys Town National Research Hospital — will take part in<\/p>\n

the research spurred by this grant is proof of the significant medical<\/p>\n

expertise in Nebraska.<\/p>\n

The four research projects are all led by junior scientists. The intent<\/p>\n

of the COBRE program is that the junior scientists would use the funding<\/p>\n

for two to three years, after which they would make a case for independent<\/p>\n

NIH funding. At that time, additional researchers would use the COBRE funds<\/p>\n

to begin their own projects. By the end of the five-year COBRE grant, those<\/p>\n

projects should compete for their own funding, as well.<\/p>\n

We hope to end up with a core of good scientists who can get competitive<\/p>\n

funding and keep the center going, Dr. Smith said.<\/p>\n

Ultimately, she said, patients who suffer from the illnesses and diseases<\/p>\n

being studied will benefit.<\/p>\n

If we can get at the genetic issues, well understand the clinical<\/p>\n

conditions better and be able to get at them, Dr. Smith said. Better<\/p>\n

clinical treatments will come about because of this work.<\/p>\n

 <\/p>\n<\/a><\/div><\/div>","protected":false},"excerpt":{"rendered":"

The University of Nebraska Medical Center learned today that it has been awarded a five-year grant totaling more than $10.6 million from the National Institutes of Health (NIH) to study genes in neurosensory systems. The grant the largest ever received by UNMC was funded through the Centers of Biomedical Research Excellence (CoBRE) program, which is […]<\/p>\n","protected":false},"author":79,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-47561","post","type-post","status-publish","format-standard","hentry","category-uncategorized","department-press-release"],"yoast_head":"\nUNMC receives $10.6 million grant from NIH to study genes in neurosensory systems<\/title>\n<meta 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