{"id":51623,"date":"2015-01-29T00:00:00","date_gmt":"2015-01-29T06:00:00","guid":{"rendered":"https:\/\/www.unmc.edu\/newsroom\/2015\/01\/29\/unmc-trial-explores-injectable-hiv-medications\/"},"modified":"2022-09-02T20:47:38","modified_gmt":"2022-09-03T01:47:38","slug":"unmc-trial-explores-injectable-hiv-medications","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/newsroom\/2015\/01\/29\/unmc-trial-explores-injectable-hiv-medications\/","title":{"rendered":"UNMC trial explores injectable HIV medications"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\"><p>\nA potential new drug-delivery system, being tested in UNMC&#039;s HIV Clinic as part of a clinical trial, might not only treat the condition, but offer additional peace of mind. In a few decades, HIV has gone from being a death sentence to a chronic condition. These days, many of us who don&#039;t have it think about it infrequently, if at all. But, those who have HIV have to think about it every time they swallow another pill. But UNMC&#039;s clinic is one of a handful of sites nationwide taking part in a clinical trial that tests the efficacy of getting periodic injections rather than taking pills. &quot;This is something that&#039;s never been done before,&quot; said Uriel Sandkovsky, M.D., assistant professor of internal medicine. &quot;Injectable medicine is something we&#039;ve been waiting for for years.&quot; These injections, theoretically, last for long periods of time. So, you&#039;re good for a good while. That way, there&#039;s no forgetting to take your pills. But, you can forget that you have to. &quot;It allows me to put that to the back of my mind,&quot; said a clinical trial participant, who asked to remain anonymous. &quot;I have had a lot of anxiety finding out that I was HIV-positive.&quot; And he would be reminded of that anxiety every time he took a pill. But, getting two shots every four weeks? &quot;For lack of a better term, I feel normal,&quot; he said. Susan Swindells, M.B.B.S., professor of internal medicine and the clinic&#039;s medical director, is not surprised. A 2012 UNMC study told her much the same thing. Given a choice, many HIV-infected patients would prefer periodic injections instead of daily pills. And, for many, it goes beyond convenience, or even peace of mind. &quot;Some have competing subsistence demands,&quot; Dr. Swindells said. &quot;They need a roof over their head and food. They&#039;re worried about the security of themselves and their children, keeping the electricity on. Medicine-taking is down the list. It gets forgotten and left off. &quot;Although this is in the early stages of development, this option, where you&#039;d come here for an injection every other month or so, would be fantastic.&quot; The drugs were developed by the pharmaceutical company ViiV, which wanted to work with UNMC on this project due to the medical center&#039;s longstanding role as a leader in HIV-drug research. Howard Gendelman, M.D., chair of pharmacology and experimental neuroscience, also is studying the ViiV drugs in his lab.<\/p>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Many patients would prefer periodic injections to daily pills.<\/p>\n","protected":false},"author":27,"featured_media":51624,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-51623","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized","department-college-of-medicine","department-internal-medicine","department-unmc-front-page","department-unmc-today-todays-headlines","department-vice-chancellor-research","author_override-kalani-simpson-unmc-public-relations"],"yoast_head":"<!-- This site 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