{"id":61940,"date":"2018-05-08T00:00:00","date_gmt":"2018-05-08T05:00:00","guid":{"rendered":"https:\/\/www.unmc.edu\/newsroom\/2018\/05\/08\/internal-medicine-research-and-non-research-awards-first-quarter-2018\/"},"modified":"2018-05-08T00:00:00","modified_gmt":"2018-05-08T05:00:00","slug":"internal-medicine-research-and-non-research-awards-first-quarter-2018","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/newsroom\/2018\/05\/08\/internal-medicine-research-and-non-research-awards-first-quarter-2018\/","title":{"rendered":"Internal Medicine Research and Non-Research Awards – First Quarter 2018"},"content":{"rendered":"

From 01\/01\/2018- To 03\/31\/2018, <\/strong><\/p>\n

Proposal Title, ID#, Sponsor, Dates, Direct Cost, Indirect Cost, Total Cost<\/strong><\/p>\n

 <\/p>\n

Burdorf, Adam F<\/strong><\/p>\n

Investigation to optimize hemodynamic management of heartmate II left ventricular assist device patients using the CardioMEMS pulmonary artery pressure sensor in advanced hart failure, 21370, St. Jude Medical Business Services, Inc., 01\/18\/18-01\/17\/20, $24,952 , $5,708 , $30,660<\/p>\n

 <\/p>\n

Desouza, Cyrus Victor<\/strong><\/p>\n

Continuation of Glycemic Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE), 15785, George Washington University, 09\/06\/17-07\/31\/18, $577,815 , $267,435 , $845,250<\/p>\n

Midwestern Collaborative for Treating Obesity in Rural Primary Care, 18181, University of Kansas Medical Center Research Institute Inc, 01\/01\/18-12\/31\/18, $123,260 , $43,509 , $166,769<\/p>\n

Investigation of efficacy and safety of three dose levels of subcutaneous semaglutide once daily versus placebo in subjects with non-alcoholic steatohepatitis., 21324, Novo Nordisk Pharmaceuticals, Inc., 01\/17\/18-01\/16\/20, $0 , $16,737 , $16,737<\/p>\n

Investigation of efficacy and safety of three dose levels of subcutaneous semaglutide once daily versus placebo in subjects with non-alcoholic steatohepatitis., 21324, Novo Nordisk Pharmaceuticals, Inc., 01\/17\/18-01\/16\/20, $86,829 , $5,579 , $92,408<\/p>\n

 <\/p>\n

Shivaswamy, Vijay<\/strong><\/p>\n

ICA William Taylor-Prominent study at VA, 21807, Nebraska Educational Biomedical Research Association, 04\/01\/18-06\/30\/19, $20,636 , $0 , $20,636<\/p>\n

ICA Ramesh Ramalingam-Prominent study at VA, 21806, Nebraska Educational Biomedical Research Association, 04\/01\/18-06\/30\/19, $56,247 , $0 , $56,247<\/p>\n

 <\/p>\n

Thomes, Paul G<\/strong><\/p>\n

Role of LipidDroplet Ubiquitylation in Hepatic Manifestation of Metabolic Syndrome, 21610, University of Nebraska – Lincoln, 12\/08\/17-05\/31\/18, $42,685 , $0 , $42,685<\/p>\n

 <\/p>\n

Bonasera, Stephen John<\/strong><\/p>\n

Live Well: A Mobile Intervention for Bipolar Disorder, 20614, Northwestern University-Chicago, 07\/01\/17-06\/30\/18, $1,861 , $940 , $2,801<\/p>\n

The Care Ecosystem: Navigating Patients and Caregivers Through Stages of Dementia Care, 21403, University of California – San Francisco, 09\/30\/17-05\/31\/18, $79,112 , $40,743 , $119,855<\/p>\n

 <\/p>\n

Florescu, Diana Florentina<\/strong><\/p>\n

A Randomized, Double-Blind, Placebo-Controlled Dose Ranging Study Evaluating the Safety, Pharmacokinetics and Clinical Benefit of FLU-IGIV in Hospitalized Patients with Serious Influenza A Infection, 21381, Emergent BioSolutions Canada Inc., 01\/03\/17-01\/02\/20, $0 , $7,736 , $7,736<\/p>\n

A Randomized, Double-Blind, Placebo-Controlled Dose Ranging Study Evaluating the Safety, Pharmacokinetics and Clinical Benefit of FLU-IGIV in Hospitalized Patients with Serious Influenza A Infection, 21381, Emergent BioSolutions Canada Inc., 01\/03\/18-01\/02\/20, $50,172 , $2,579 , $52,751<\/p>\n

A Phase III, Randomized, Double-Blinde, Active Comparator-Controlled Study to Evaluate the Efficacy and Safety of MK-8228 (Letermovir) Versus Valganciclovir for the Prevention of Human Cytomegalovirus (CMV) Disease in Adult Kidney Transplant Recipients, 21422, Merck Sharp & Dohme Corp., 03\/23\/18-03\/22\/20, $0 , $36,398 , $36,398<\/p>\n

A Phase III, Randomized, Double-Blinde, Active Comparator-Controlled Study to Evaluate the Efficacy and Safety of MK-8228 (Letermovir) Versus Valganciclovir for the Prevention of Human Cytomegalovirus (CMV) Disease in Adult Kidney Transplant Recipients, 21422, Merck Sharp & Dohme Corp., 03\/23\/18-03\/22\/20, $189,654 , $12,132 , $201,786<\/p>\n

 <\/p>\n

Kalil, Andre C<\/strong><\/p>\n

Rapid Assessment of Acute Illness and Injury to Enhance the U.S. Response to Public Health Emergencies, 21720, University of Southern California, 08\/01\/17-07\/31\/18, $9,435 , $4,859 , $14,294<\/p>\n

(ARLG) Antibacterial Resistance Leadership Group: Achaogen Lung PK, 20336, Duke University, 12\/01\/17-11\/30\/18, $22,664 , $11,672 , $34,336<\/p>\n

 <\/p>\n

Rupp, Mark E<\/strong><\/p>\n

NEBRASKA ANTIMICROBIAL STEWARDSHIP ASSESSMENT AND PROMOTION (NEBRASKA ASAP) SUBAWARD, 21053, NE DHHS, 08\/01\/17-07\/31\/18, $499,589 , $14,171 , $513,760<\/p>\n

 <\/p>\n

Swindells, Susan<\/strong><\/p>\n

National AIDS Education and Training Center Grants, 530, University of Illinois – Chicago, 07\/01\/17-06\/30\/18, $48,687 , $3,895 , $52,582<\/p>\n

AIDS Clinical Trials Group Network (ACTG), 16481, Brigham & Women's Hospital, 12\/01\/17-11\/30\/18, $16,795 , $8,489 , $25,284<\/p>\n

AIDS Clinical Trials Group (ACTG): Protocol Chair Support, 20097, Brigham & Women's Hospital, 12\/01\/17-11\/30\/18, $3,128 , $1,575 , $4,703<\/p>\n

Title III:Categorical Grant Program to Provide Outpatient Early Intervention Services with Respect to HIV Disease (Ryan White Part C Outpatient EIS Program), 6247, DHHS\/HRSA, 01\/01\/18-12\/31\/18, $307,305 , $0 , $307,305<\/p>\n

 <\/p>\n

Vanschooneveld, Trevor Craig<\/strong><\/p>\n

Zerbaxa Medication Use Evaluation, 21321, Merck & Co, Inc., 01\/30\/18-01\/29\/20, $36,976 , $9,354 , $46,330<\/p>\n

 <\/p>\n

Baljevic, Muhamed<\/strong><\/p>\n

A Phase I\/II Study of the c-Met Inhibitor Cabozantinib as a Targeted Strategy to Reverse Resistance to the Proteasome Inhibitor Carfilzomib in Refractory Multiple Myeloma, 21246, Amgen, Inc., 02\/21\/18-02\/18\/20, $0 , $26,224 , $26,224<\/p>\n

A Phase I\/II Study of the c-Met Inhibitor Cabozantinib as a Targeted Strategy to Reverse Resistance to the Proteasome Inhibitor Carfilzomib in Refractory Multiple Myeloma, 21246, Amgen, Inc., 02\/21\/18-02\/18\/20, $137,484 , $8,742 , $146,226<\/p>\n

 <\/p>\n

Bhatt, Vijaya R<\/strong><\/p>\n

A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Phase III Trial of the FLT3 Inhibitor Gilteritinib Administered as Maintenance Therapy Following Allogeneic Transplant for Patients with FLT3-ITD AML, 21280, National Marrow Donor Program, 12\/19\/17-12\/18\/18, $82,729 , $20,730 , $103,459<\/p>\n

 <\/p>\n

Grem, Jean Linette<\/strong><\/p>\n

An Open Label Randomized Phase I\/II Trial of MLN0128 Compared to Sorafenib in Patients with Advanced or Metastatic Hepatocellular Carcinoma: Big Ten Cancer Research Consortium BTCRC-GI13-002, 21526, Hoosier Oncology Group, LLC, 01\/26\/18-01\/25\/19, $29,572 , $7,429 , $37,001<\/p>\n

Gundabolu, Krishna<\/strong><\/p>\n

A Phase Ib Study of Ruxolitinib in Combination with PUH71 for the treatment of Subjects with PrimaryMyelofibrosis (PMF), Post-Polycythemia Vera MF (post- PV MF), and Post-Essential Thrombocythemia MF (post- ET MF), 21450, Samus Therapeutics, Inc., 03\/12\/18-03\/11\/20, $0 , $63,295 , $63,295<\/p>\n

A Phase Ib Study of Ruxolitinib in Combination with PUH71 for the treatment of Subjects with PrimaryMyelofibrosis (PMF), Post-Polycythemia Vera MF (post- PV MF), and Post-Essential Thrombocythemia MF (post- ET MF), 21450, Samus Therapeutics, Inc., 03\/12\/18-03\/11\/20, $327,591 , $21,099 , $348,690<\/p>\n

 <\/p>\n

Lunning, Matthew A<\/strong><\/p>\n

An Open-Label, Dose Escalation and Dose Expansion Trial Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of Orally Administered CA-4948 in Patients with Relapsed or Refractory Non Hodgkin Lymphoma, 21385, Curis, Inc., 12\/19\/17-12\/18\/19, $0 , $57,676 , $57,676<\/p>\n

An Open-Label, Dose Escalation and Dose Expansion Trial Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of Orally Administered CA-4948 in Patients with Relapsed or Refractory Non Hodgkin Lymphoma, 21385, Curis, Inc., 12\/19\/17-12\/18\/19, $298,772 , $19,225 , $317,997<\/p>\n

 <\/p>\n

Teply, Benjamin Addison<\/strong><\/p>\n

Phase II Study of Olaparib in Men with High-Risk Biochemically-Recurrent Prostate Cancer Following Radical Prostatectomy, with Integrated Biomarker Analysis, 21405, Johns Hopkins University, 01\/16\/18-01\/15\/20, $0 , $14,236 , $14,236<\/p>\n

Phase II Study of Olaparib in Men with High-Risk Biochemically-Recurrent Prostate Cancer Following Radical Prostatectomy, with Integrated Biomarker Analysis, 21405, Johns Hopkins University, 01\/16\/18-01\/15\/20, $76,005 , $4,745 , $80,750<\/p>\n

 <\/p>\n

Murphy, P. James <\/strong> <\/p>\n

A CF C3N Care Model of the Future: Proposal for Piloting a Learning Health System, 20461, Cincinnati Children's Hospital Medical Center, 01\/01\/18-12\/31\/18, $30,000 , $2,400 , $32,400<\/p>\n

A Multi-Center, Randomized, Placebo-Controlled, Phase 1, Two-Part Study Designed to Assess the Safety, Tolerability, Pharmacokinetics, Food Effect, and Drug-Drug Interactions of PTI-801 in Healthy Volunteers, and Safety, Tolerability, and Pharmacokinetics, 21339, Proteostasis Therapeutics, Inc., 01\/01\/18-12\/31\/20, $0 , $9,746 , $9,746<\/p>\n

A Multi-Center, Randomized, Placebo-Controlled, Phase 1, Two-Part Study Designed to Assess the Safety, Tolerability, Pharmacokinetics, Food Effect, and Drug-Drug Interactions of PTI-801 in Healthy Volunteers, and Safety, Tolerability, and Pharmacokinetics, 21339, Proteostasis Therapeutics, Inc., 01\/01\/18-12\/31\/20, $52,979 , $3,249 , $56,228<\/p>\n

 <\/p>\n

Poole, Jill Adair<\/strong><\/p>\n

Role of Pattern Recognition Receptors in Organic Dust-induced Airway Inflammation, 14123, DHHS\/NIH\/NIEHS, 01\/01\/18-12\/31\/18, $287,070 , $144,970 , $432,040<\/p>\n

 <\/p>\n

Rennard, Stephen Israel<\/strong><\/p>\n

Network Management Core (NEMO) for the Pulmonary Trials Cooperative (PTC), 19461, University of Pittsburgh, 08\/01\/17-07\/31\/18, $6,839 , $3,454 , $10,293<\/p>\n

RofLumilast orAzithromycin to prevent COPD Exacerbations (RELIANCE) Study, 19378, University of Illinois – Chicago, 11\/29\/17-12\/15\/18, $12,330 , $4,932 , $17,262<\/p>\n

 <\/p>\n

Thompson, Austin Bassett<\/strong><\/p>\n

A double blind, randomized, placebo-controlled trial evaluating the efficacy and safety of nintedanib over 52 weeks in patients with Progressive Fibrosing Interstitial Lung Disease (PF-ILD), 20845, Boehringer Ingelheim Pharmaceuticals, Inc., 01\/01\/18-12\/31\/20, $0 , $13,181 , $13,181<\/p>\n

A double blind, randomized, placebo-controlled trial evaluating the efficacy and safety of nintedanib over 52 weeks in patients with Progressive Fibrosing Interstitial Lung Disease (PF-ILD), 20845, Boehringer Ingelheim Pharmaceuticals, Inc., 01\/01\/18-12\/31\/20, $70,596 , $4,394 , $74,990<\/p>\n

A multi-center, double-blind, placebo-controlled, Phase 4 study in patients with pulmonary arterial hypertension to assess the effect of selexipag on daily life physical activity and patients self-reported symptoms and their impacts, 21200, Actelion Pharmaceuticals Ltd., 02\/09\/18-11\/30\/19, $0 , $13,309 , $13,309<\/p>\n

A multi-center, double-blind, placebo-controlled, Phase 4 study in patients with pulmonary arterial hypertension to assess the effect of selexipag on daily life physical activity and patients self-reported symptoms and their impacts, 21200, Actelion Pharmaceuticals Ltd., 02\/09\/18-11\/30\/19, $71,250 , $4,436 , $75,686<\/p>\n

 <\/p>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"

From 01\/01\/2018- To 03\/31\/2018, Proposal Title, ID#, Sponsor, Dates, Direct Cost, Indirect Cost, Total Cost   Burdorf, Adam F Investigation to optimize hemodynamic management of heartmate II left ventricular assist device patients using the CardioMEMS pulmonary artery pressure sensor in advanced hart failure, 21370, St. Jude Medical Business Services, Inc., 01\/18\/18-01\/17\/20, $24,952 , $5,708 , […]<\/p>\n","protected":false},"author":123,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-61940","post","type-post","status-publish","format-standard","hentry","category-uncategorized","department-internal-medicine-newsletter"],"yoast_head":"\nInternal Medicine Research and Non-Research Awards - 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