{"id":63958,"date":"2019-01-21T00:00:00","date_gmt":"2019-01-21T06:00:00","guid":{"rendered":"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/"},"modified":"2022-08-29T15:59:57","modified_gmt":"2022-08-29T20:59:57","slug":"research-highlights-62","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/","title":{"rendered":"Research highlights"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\"><p>UNMC College of Medicine faculty received 17 grant awards representing more than $4.2 million in new funding during the month of November.<br \/>\n&nbsp;<br \/>\nHere&rsquo;s a brief summary of the largest grant received:<br \/>\n&nbsp;<br \/>\n<strong>Tony Wilson, PhD<\/strong>, neurological sciences, has received a National Institutes of Health award for $2.4 million from the National Institute of Mental Health to use magnetoencephalography to study the role that spontaneous spiking activity of human cortical neurons plays in information processing.<br \/>\n&nbsp;<br \/>\n<strong>Industry-sponsored grants:<\/strong><br \/>\n<strong>&nbsp;<\/strong><br \/>\nThe following industry-sponsored contracts and foundation grants were received.&nbsp; Information on clinical trials enrolling patients at UNMC can be found <a href=\"http:\/\/net.unmc.edu\/ctsearch\/index_unmc.php\">here<\/a>.<br \/>\n&nbsp;<br \/>\n<strong>Cyrus Desouza, MBBS<\/strong>, internal medicine &#8211; diabetes, endocrinology and metabolism, is the UNMC lead on a clinical study of a novel use for a type-2 diabetes drug to determine if it could be used to reduce the risk of cardiovascular events in overweight or obese patients with prior cardiovascular disease.<br \/>\n&nbsp;<br \/>\n<strong>Matthew Lunning, DO<\/strong>, internal medicine &#8211; oncology\/hematology, is the UNMC lead on a phase III clinical trial that will compare the current standard of care against the use of a new treatment in patients with relapsed or refractory aggressive non-Hodgkin lymphoma.<br \/>\n<strong>&nbsp;<\/strong><br \/>\n<strong>Joshua Santarpia, PhD<\/strong>, pathology &amp; microbiology, has received three separate task orders through the National Strategic Research Institute for studies on biological countermeasure development, biological sampler development, and perimeter defense.<br \/>\n<strong>&nbsp;<\/strong><br \/>\n<strong>Weining Zhen, MD<\/strong>, radiation oncology,<strong> <\/strong>is the UNMC lead on a phase I\/II clinical trial of a combination radiation and drug therapy in patients with locally advanced head and neck cancer.<br \/>\n&nbsp;<br \/>\n<strong>Zaid Al-Kadhimi, MD<\/strong>, internal medicine &#8211; oncology\/hematology, is the UNMC lead on a phase III clinical study of a novel drug to be used prior to allogeneic hematopoietic cell transplantation in older patients with acute myeloid leukemia.<br \/>\n&nbsp;<br \/>\n<strong>Xiaowei Li, PhD<\/strong>, neurological sciences, has received funding from the American Heart Association for a study titled, &quot;Promoting Organization and Integration of Transplanted Stem Cells for Brain Tissue Regeneration after Stroke.&quot;<br \/>\n<strong>&nbsp;<\/strong><br \/>\n<strong>Philip Bierman, MD<\/strong>, internal medicine &#8211; oncology\/hematology,<strong> <\/strong>has received funding through the Mayo Clinic to serve as the UNMC lead on their phase II clinical trial of a combination therapy in patients with early-stage Hodgkin lymphoma.<br \/>\n&nbsp;<br \/>\n<strong>Hani Haider, PhD<\/strong>, orthopaedic surgery, has received support to perform strength and constraint testing on a total knee replacement system.<br \/>\n&nbsp;<br \/>\n<strong>Bracha Goldsweig, MD<\/strong>, pediatrics &#8211; endocrine, has received support from the Cystic Fibrosis Foundation for a study that will measure beta cell death in individuals with cystic fibrosis.<br \/>\n&nbsp;<br \/>\n<strong>Jeffrey Cooper, MD<\/strong>, emergency medicine, has received support from the University of Minnesota to assist with their hyperbaric oxygen brain injury treatment trial.<br \/>\n&nbsp;<br \/>\n<strong>Gwenn Skar, MD<\/strong>, pediatrics &#8211; infectious diseases, has received support through the University of Arkansas to study whether attenuated inflammation is protective in a certain type of bacterial infection of the central nervous system in infants.<br \/>\n&nbsp;<br \/>\n<strong>Scott Koepsell, MD, PhD<\/strong>, pathology &amp; microbiology, has received support to validate the clinical performance of new diagnostic assays on fresh and frozen tissue samples.<br \/>\n<strong>&nbsp;<\/strong><br \/>\n<strong>Shelby Kutty, MD, PhD<\/strong>, pediatrics &#8211; cardiology, has received support from the Children&rsquo;s Hospital &amp; Medical Center Foundation for a study titled, &quot;Inhibition of Drp1 Improves Diastolic Function in a Porcine Model of Right Ventricular Ischemia-Reperfusion Injury.&quot;<br \/>\n&nbsp;<br \/>\n<strong>Marshall Hyden, MD<\/strong>, internal medicine &#8211; cardiovascular, has received support through the Centre of Excellence for the Prevention of Organ Failure to assist in their clinical study of a novel multi-marker blood test for acute cardiac transplant rejection.<\/p>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Tony Wilson, Ph.D., landed a $2.4 million grant from the National Institutes of Health to continue his cutting-edge brain research.<\/p>\n","protected":false},"author":78,"featured_media":63959,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-63958","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized","department-intercom"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Research highlights<\/title>\n<meta name=\"description\" content=\"Tony Wilson, Ph.D., landed a $2.4 million grant from the National Institutes of Health to continue his cutting-edge brain research.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research highlights\" \/>\n<meta property=\"og:description\" content=\"Tony Wilson, Ph.D., landed a $2.4 million grant from the National Institutes of Health to continue his cutting-edge brain research.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/\" \/>\n<meta property=\"og:site_name\" content=\"Newsroom\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/unmcedu\" \/>\n<meta property=\"article:published_time\" content=\"2019-01-21T06:00:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-08-29T20:59:57+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.unmc.edu\/newsroom\/wp-content\/uploads\/2019\/01\/TonyWilson1_19.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"705\" \/>\n\t<meta property=\"og:image:height\" content=\"406\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Tom O&#039;Connor\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@unmc\" \/>\n<meta name=\"twitter:site\" content=\"@unmc\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Tom O&#039;Connor\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/\"},\"author\":{\"name\":\"Tom O'Connor\",\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/#\/schema\/person\/8171e6fec87d2b600ff48511fa418536\"},\"headline\":\"Research highlights\",\"datePublished\":\"2019-01-21T06:00:00+00:00\",\"dateModified\":\"2022-08-29T20:59:57+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/\"},\"wordCount\":589,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.unmc.edu\/newsroom\/wp-content\/uploads\/2019\/01\/TonyWilson1_19.jpg\",\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/\",\"url\":\"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/\",\"name\":\"Research highlights\",\"isPartOf\":{\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.unmc.edu\/newsroom\/wp-content\/uploads\/2019\/01\/TonyWilson1_19.jpg\",\"datePublished\":\"2019-01-21T06:00:00+00:00\",\"dateModified\":\"2022-08-29T20:59:57+00:00\",\"description\":\"Tony Wilson, Ph.D., landed a $2.4 million grant from the National Institutes of Health to continue his cutting-edge brain research.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/#primaryimage\",\"url\":\"https:\/\/www.unmc.edu\/newsroom\/wp-content\/uploads\/2019\/01\/TonyWilson1_19.jpg\",\"contentUrl\":\"https:\/\/www.unmc.edu\/newsroom\/wp-content\/uploads\/2019\/01\/TonyWilson1_19.jpg\",\"width\":705,\"height\":406},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.unmc.edu\/newsroom\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Research highlights\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/#website\",\"url\":\"https:\/\/www.unmc.edu\/newsroom\/\",\"name\":\"Newsroom\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.unmc.edu\/newsroom\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/#organization\",\"name\":\"University of Nebraska Medical Center\",\"url\":\"https:\/\/www.unmc.edu\/newsroom\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.unmc.edu\/newsroom\/wp-content\/uploads\/2022\/08\/overview-1.png\",\"contentUrl\":\"https:\/\/www.unmc.edu\/newsroom\/wp-content\/uploads\/2022\/08\/overview-1.png\",\"width\":500,\"height\":153,\"caption\":\"University of Nebraska Medical Center\"},\"image\":{\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/unmcedu\",\"https:\/\/x.com\/unmc\",\"https:\/\/instagram.com\/iamunmc\",\"https:\/\/www.youtube.com\/user\/UNMCEDU\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.unmc.edu\/newsroom\/#\/schema\/person\/8171e6fec87d2b600ff48511fa418536\",\"name\":\"Tom O'Connor\",\"url\":\"https:\/\/www.unmc.edu\/newsroom\/author\/35f4a8d465e6e1edc05f3d8ab658c551\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Research highlights","description":"Tony Wilson, Ph.D., landed a $2.4 million grant from the National Institutes of Health to continue his cutting-edge brain research.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/","og_locale":"en_US","og_type":"article","og_title":"Research highlights","og_description":"Tony Wilson, Ph.D., landed a $2.4 million grant from the National Institutes of Health to continue his cutting-edge brain research.","og_url":"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/","og_site_name":"Newsroom","article_publisher":"https:\/\/www.facebook.com\/unmcedu","article_published_time":"2019-01-21T06:00:00+00:00","article_modified_time":"2022-08-29T20:59:57+00:00","og_image":[{"width":705,"height":406,"url":"https:\/\/www.unmc.edu\/newsroom\/wp-content\/uploads\/2019\/01\/TonyWilson1_19.jpg","type":"image\/jpeg"}],"author":"Tom O'Connor","twitter_card":"summary_large_image","twitter_creator":"@unmc","twitter_site":"@unmc","twitter_misc":{"Written by":"Tom O'Connor","Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/#article","isPartOf":{"@id":"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/"},"author":{"name":"Tom O'Connor","@id":"https:\/\/www.unmc.edu\/newsroom\/#\/schema\/person\/8171e6fec87d2b600ff48511fa418536"},"headline":"Research highlights","datePublished":"2019-01-21T06:00:00+00:00","dateModified":"2022-08-29T20:59:57+00:00","mainEntityOfPage":{"@id":"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/"},"wordCount":589,"commentCount":0,"publisher":{"@id":"https:\/\/www.unmc.edu\/newsroom\/#organization"},"image":{"@id":"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/#primaryimage"},"thumbnailUrl":"https:\/\/www.unmc.edu\/newsroom\/wp-content\/uploads\/2019\/01\/TonyWilson1_19.jpg","inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/","url":"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/","name":"Research highlights","isPartOf":{"@id":"https:\/\/www.unmc.edu\/newsroom\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/#primaryimage"},"image":{"@id":"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/#primaryimage"},"thumbnailUrl":"https:\/\/www.unmc.edu\/newsroom\/wp-content\/uploads\/2019\/01\/TonyWilson1_19.jpg","datePublished":"2019-01-21T06:00:00+00:00","dateModified":"2022-08-29T20:59:57+00:00","description":"Tony Wilson, Ph.D., landed a $2.4 million grant from the National Institutes of Health to continue his cutting-edge brain research.","breadcrumb":{"@id":"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/#primaryimage","url":"https:\/\/www.unmc.edu\/newsroom\/wp-content\/uploads\/2019\/01\/TonyWilson1_19.jpg","contentUrl":"https:\/\/www.unmc.edu\/newsroom\/wp-content\/uploads\/2019\/01\/TonyWilson1_19.jpg","width":705,"height":406},{"@type":"BreadcrumbList","@id":"https:\/\/www.unmc.edu\/newsroom\/2019\/01\/21\/research-highlights-62\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.unmc.edu\/newsroom\/"},{"@type":"ListItem","position":2,"name":"Research highlights"}]},{"@type":"WebSite","@id":"https:\/\/www.unmc.edu\/newsroom\/#website","url":"https:\/\/www.unmc.edu\/newsroom\/","name":"Newsroom","description":"","publisher":{"@id":"https:\/\/www.unmc.edu\/newsroom\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.unmc.edu\/newsroom\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.unmc.edu\/newsroom\/#organization","name":"University of Nebraska Medical Center","url":"https:\/\/www.unmc.edu\/newsroom\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.unmc.edu\/newsroom\/#\/schema\/logo\/image\/","url":"https:\/\/www.unmc.edu\/newsroom\/wp-content\/uploads\/2022\/08\/overview-1.png","contentUrl":"https:\/\/www.unmc.edu\/newsroom\/wp-content\/uploads\/2022\/08\/overview-1.png","width":500,"height":153,"caption":"University of Nebraska Medical Center"},"image":{"@id":"https:\/\/www.unmc.edu\/newsroom\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/unmcedu","https:\/\/x.com\/unmc","https:\/\/instagram.com\/iamunmc","https:\/\/www.youtube.com\/user\/UNMCEDU"]},{"@type":"Person","@id":"https:\/\/www.unmc.edu\/newsroom\/#\/schema\/person\/8171e6fec87d2b600ff48511fa418536","name":"Tom O'Connor","url":"https:\/\/www.unmc.edu\/newsroom\/author\/35f4a8d465e6e1edc05f3d8ab658c551\/"}]}},"_links":{"self":[{"href":"https:\/\/www.unmc.edu\/newsroom\/wp-json\/wp\/v2\/posts\/63958","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.unmc.edu\/newsroom\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.unmc.edu\/newsroom\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/newsroom\/wp-json\/wp\/v2\/users\/78"}],"replies":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/newsroom\/wp-json\/wp\/v2\/comments?post=63958"}],"version-history":[{"count":1,"href":"https:\/\/www.unmc.edu\/newsroom\/wp-json\/wp\/v2\/posts\/63958\/revisions"}],"predecessor-version":[{"id":84718,"href":"https:\/\/www.unmc.edu\/newsroom\/wp-json\/wp\/v2\/posts\/63958\/revisions\/84718"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.unmc.edu\/newsroom\/wp-json\/wp\/v2\/media\/63959"}],"wp:attachment":[{"href":"https:\/\/www.unmc.edu\/newsroom\/wp-json\/wp\/v2\/media?parent=63958"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.unmc.edu\/newsroom\/wp-json\/wp\/v2\/categories?post=63958"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.unmc.edu\/newsroom\/wp-json\/wp\/v2\/tags?post=63958"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}