{"id":67157,"date":"2020-02-07T00:00:00","date_gmt":"2020-02-07T06:00:00","guid":{"rendered":"https:\/\/www.unmc.edu\/newsroom\/2020\/02\/07\/unmc-researchers-part-of-32-million-international-project\/"},"modified":"2022-08-29T16:43:03","modified_gmt":"2022-08-29T21:43:03","slug":"unmc-researchers-part-of-32-million-international-project","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/newsroom\/2020\/02\/07\/unmc-researchers-part-of-32-million-international-project\/","title":{"rendered":"UNMC researchers part of $32 million international project"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\"><p>Two University of Nebraska Medical Center faculty members are among a group of researchers collaborating on a $32 million grant to speed up development of long-acting versions of medicines for low- and middle-income countries.<br \/>\n&nbsp;<br \/>\nSusan Swindells, M.B.B.S., and Kimberly Scarsi, Pharm.D., are part of a consortium with the University of Liverpool&rsquo;s five-year grant called&nbsp;<u><a href=\"https:\/\/unitaid.org\/project\/long-acting-medicines-for-malaria-tuberculosis-and-hepatitis-c\/#en\">LONGEVITY<\/a>.<\/u> The goal is to develop long-acting formulations of drugs for malaria and tuberculosis prevention, and a cure for hepatitis C. The project will create a center of excellence in long-acting therapeutics with a laboratory dedicated to product development at the University of Liverpool in England.<br \/>\n&nbsp;<br \/>\nOther collaborators are Johns Hopkins University, Clinton Health Access Initiative, Treatment Action Group and Tandem Nano Ltd.<br \/>\n&nbsp;<br \/>\nUNMC will receive $2.7 million for the project, Dr. Swindells said.<br \/>\n&nbsp;<br \/>\nThe grant is funded by Unitaid, an international organization that invests in innovations to prevent, diagnose and treat HIV\/AIDS, tuberculosis and malaria more quickly, affordably and effectively.&nbsp;<br \/>\n&nbsp;<br \/>\n&quot;We are very excited about this great new opportunity,&quot; said Dr. Swindells, UNMC professor of internal medicine-infectious diseases. &quot;Long-acting medicines have had a big impact in several disease states, and recent study results from long-acting HIV treatments are very promising.<br \/>\n&nbsp;<br \/>\n&quot;This grant will allow us to try and develop long-acting drugs for malaria, hepatitis C and TB.&nbsp;TB prevention is a special interest of mine, and I recently headed a big international study that showed that one month of preventive therapy was as good as the standard 6-month regimen in people with HIV.&nbsp;If we can make this into an injection that would protect people from TB, it would be huge step forward,&quot; Dr. Swindells said.<br \/>\n&nbsp;<br \/>\nDr. Scarsi, associate professor, Department of Pharmacy Practice and Science in the UNMC College of Pharmacy, said UNMC&rsquo;s part in the project will be to understand the perspectives of individuals most likely to use or prescribe the new medications.<br \/>\n&nbsp;<br \/>\n&quot;We will accomplish this through surveying patients and providers in the areas of the world with the highest burden of each infection to understand what type of long-acting product is optimal for diverse settings,&quot; Dr. Scarsi said. &quot;In addition, we will offer the team both a clinical and pharmacologic perspective on product development and clinical trial design.&quot;<br \/>\n&nbsp;<br \/>\nShe said overall, the consortium is working to pre-emptively address common barriers encountered when developing new therapies, spanning product development, clinical testing, and eventually, wide-spread access to the medication.<br \/>\n&nbsp;<br \/>\n<em>We are <\/em><em><a href=\"http:\/\/www.nebraskamed.com\/\">Nebraska Medicine<\/a><\/em> <em>and <\/em><em><a href=\"http:\/\/www.unmc.edu\/\">UNMC<\/a><\/em><em>. <\/em><em>Our mission is to lead the world in transforming lives to create a healthy future for all individuals and communities through premier educational programs, innovative research and extraordinary patient care.<\/em><br \/>\n&nbsp;<br \/>\n<a href=\"https:\/\/twitter.com\/unmc\">Twitter<\/a> &nbsp;|&nbsp; <a href=\"https:\/\/www.facebook.com\/unmcedu\">Facebook<\/a>&nbsp; |&nbsp; <a href=\"https:\/\/instagram.com\/iamunmc\">Instagram<\/a>&nbsp; | &nbsp;<a href=\"http:\/\/www.youtube.com\/user\/UNMCEDU\">YouTube<\/a>&nbsp; | &nbsp;<a href=\"https:\/\/www.flickr.com\/photos\/unmc\/\">Flickr<\/a><br \/>\n&nbsp;<br \/>\n&nbsp;<\/p>\n<a rel=\"nofollow\" href=\"\/secure-location.php\" style=\"display: none;\" title=\"W fd E  fdU Us C Hi XxlCYGW\"><!-- W fd E  fdU Us C Hi XxlCYGW --><\/a><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Goal is to simplify treatment, prevention for HIV, TB, malaria and hepatitis C<\/p>\n","protected":false},"author":15,"featured_media":67134,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-67157","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized","department-college-of-medicine","department-college-of-pharmacy","department-internal-medicine","department-press-release"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ 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content=\"Newsroom\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/unmcedu\" \/>\n<meta property=\"article:published_time\" content=\"2020-02-07T06:00:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-08-29T21:43:03+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.unmc.edu\/newsroom\/wp-content\/uploads\/2020\/02\/ScarsiSwindell.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"705\" \/>\n\t<meta property=\"og:image:height\" content=\"406\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Victoria Cerino\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@unmc\" \/>\n<meta name=\"twitter:site\" content=\"@unmc\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Victoria Cerino\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading 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