{"id":68778,"date":"2020-08-31T00:00:00","date_gmt":"2020-08-31T05:00:00","guid":{"rendered":"https:\/\/www.unmc.edu\/newsroom\/2020\/08\/31\/collaborative-study-finds-antibiotics-in-watersheds\/"},"modified":"2022-09-02T17:37:02","modified_gmt":"2022-09-02T22:37:02","slug":"collaborative-study-finds-antibiotics-in-watersheds","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/newsroom\/2020\/08\/31\/collaborative-study-finds-antibiotics-in-watersheds\/","title":{"rendered":"Collaborative study finds antibiotics in watersheds"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\"><p>A multi-campus collaboration among University of Nebraska system faculty, led by the UNMC College of Allied Health Professions (CAHP), has found <a href=\"https:\/\/app1.unmc.edu\/PublicAffairs\/TodaySite\/images\/siteimages\/IDWeek083120.pdf\" target=\"_blanK\" rel=\"noopener\">antibiotics used in human treatment in two Nebraska agricultural water systems<\/a>, near Fremont and Lincoln watersheds.<br \/>\n<P>The finding of these antibiotics is deeply concerning, said Wayne Mathews, associate professor and director of research, CAHP physician assistant education.<br \/>\n<P>&#8220;It likely could have an impact on our increasing resistance to antibiotics,&#8221; Mathews said.<br \/>\n<P>&#8220;As clinicians, we hear frequent warnings not to overprescribe antibiotics, and I totally agree with that,&#8221; Mathews said. &#8220;But, for example, more than 30 percent of common UTI (urinary tract) infections show resistance to antibiotic treatment.&#8221; That&#8217;s likely more than overprescribing, <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6017557\/\">according to recent research<\/a>, Mathews said.<br \/>\n<P>And the same study shows that high rates of antibiotic resistance are found in agricultural areas.<br \/>\n<P>So, the NU team did a two-year intensive analysis of the Elkhorn River and Shell Creek watersheds.<br \/>\n<P>In addition to Mathews, the team included:<br \/>\n<UL><LI>UNMC microbiologist Linsey Donner, assistant professor, CAHP medical laboratory science;<\/p>\n<li>University of Nebraska-Lincoln civil and environmental engineer Xu Li, PhD;\n<li>UNL civil and environmental engineer Shannon Bartelt-Hunt, PhD;\n<li>UNL analytical chemist Dan Snow, PhD;\n<li>UNL postdoctoral research associate Jodi Sangster, PhD<\/ul>\n<p>&#8220;It&#8217;s a broad team of experts representing a number of pertinent fields and a great example of what we can achieve working together through <a href=\"https:\/\/nebraska.edu\/-\/media\/projects\/unca\/docs\/collaboration-initiative\/2017-2018_nri_collaboration_initiative_system_science_rfa.pdf?la=en\">System Science grants<\/a>,&#8221; Mathews said.<\/p>\n<p>The findings are significant. The U.S. Food and Drug Administration (FDA) has set up safeguards to keep human antibiotics out of agriculture and thus out of our bodies without a prescription.<\/p>\n<p>But the University of Nebraska team findings show these safeguards aren&#8217;t working. Bacteria with an antibiotic-resistant gene is &#8220;going directly into drinking water and agricultural water,&#8221; Mathews said.<\/p>\n<p>A 2017 FDA regulation requires that any antibiotics in agricultural feed must be prescribed by a veterinarian (and thus not be one used for human care) and should be related to treating or preventing a specific disease.<\/p>\n<p>How does the FDA keep track? &#8220;The FDA&#8217;s method of measuring was to look at regional antibiotic purchases divided by the biomass,&#8221; or number of livestock in the region, Mathews said.<\/p>\n<p>&#8220;<a href=\"https:\/\/amr2020-iastate.ipostersessions.com\/Default.aspx?s=B5-76-83-6D-A4-E6-B2-C9-56-F5-AD-9E-BE-6A-B5-39\">What we found<\/a>,&#8221; Mathews said, &#8220;is that method does not guarantee that there are not high levels of antibiotics of human significance in the water,&#8221; as mandated by the FDA.<\/p>\n<p>The team presented its findings at the National Institute of Antimicrobial Resistance Research and Education&#8217;s (NIAMRRE) annual conference and has been accepted at IDWeek, a prestigious infectious disease conferences, to be published in its Infectious Disease Abstracts.<\/p>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>College of Allied Health Professions leading multi-campus research effort.<\/p>\n","protected":false},"author":27,"featured_media":68779,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-68778","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized","topic-inside-unmc","topic-research","department-college-of-allied-health-professions","department-unmc-today-todays-headlines","department-vice-chancellor-research","author_override-kalani-simpson-unmc-strategic-communications"],"yoast_head":"<!-- This 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