{"id":69880,"date":"2021-01-15T00:00:00","date_gmt":"2021-01-15T06:00:00","guid":{"rendered":"https:\/\/www.unmc.edu\/newsroom\/2021\/01\/15\/research-highlights-77\/"},"modified":"2022-08-29T17:01:46","modified_gmt":"2022-08-29T22:01:46","slug":"research-highlights-77","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/newsroom\/2021\/01\/15\/research-highlights-77\/","title":{"rendered":"Research highlights"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\"><p>The UNMC College of Medicine received new grant and funding awards representing $6,868,743 in new funding in November.<\/p>\n<ul>\n<li><B>Jana Broadhurst, MD, PhD<\/b>, pathology and microbiology, received a grant of $225,265 from the National Strategic Research Institute for independent verification and validation pipeline.\n<li><B>Pierre Fayad, MD<\/b>, neurological sciences, received a grant of $10,213 from the University of Cincinnati to study anticoagulaton in intracerebral hemorrhage (ICH) survivors for stroke and recovery (ASPIRE).\n<li><b>Diana Florescu, MD<\/b>, internal medicine-infectious diseases, received a grant of $3,832,501 from the Fred Hutchinson Cancer Research Center for a phase 3 study to evaluate the efficacy, safety, and immunogencitiy of SARS-CoV-2 recombinant spike protein nanoparticle vaccine (SARS-CoV-rS) with matrix M1 adjuvant in adult participants older than 18 years.\n<li><B>Rebecca Deegan, PhD<\/b>, biochemistry and molecular biology, received a NASA Nebraska Space Grant Fellowship with an award of $7,500.\n<li><b>Stacey Gilk, PhD<\/b>, pathology\/microbiology, received a grant of $359,036 from DHHS\/NIH\/AID to study coxiella manipulation of cholesterol in the intracellular niche.<br \/>\n<LI><b>Jason MacTaggart, MD<\/b>, surgery-vascular surgery, received a grant of $166,309 from the University of Nebraska at Omaha for optimized stents for the femoropopliteal artery.<\/p>\n<li><B>Sidharth Mahapatra, MD, PhD<\/b>, pediatrics critical care, received a grant of $57,954 from the Nebraska DHHS for a study of NFIB&#8217;s role in medulloblastoma stem cell renewal; and a grant of $23,000 from the University of Pennsylvania for PROSpect (Prone and Oscillation Pediatric Clinical Trial).\n<li><b>James McClay, MD<\/b>, emergency medicine, received a grant of $180,921 from West Virginia University for the IDeA clinical and translational research units join the National COVID Cohort Collaborative.\n<li><b>Alicia Schiller, PhD<\/b>, anesthesiology, received a grant of $107,206 from the National Strategic Research Institute for the assessment and training of procedural skills for combat casualty care.\n<li><B>Christopher Smith, MD<\/b>, internal medicine-hospital medicine, received a grant of $2,420 from Oregon Health and Science University for Just in Time! Evaluating the effect of a structured training on resident point-of-care ultrasound use.<\/ul>\n<p><b>Industry-sponsored grants and contracts:<\/b><\/p>\n<p>The following industry-sponsored contracts and foundation grants were received. Information on clinical trials enrolling patients at UNMC can be found <a href=\"https:\/\/www.unmc.edu\/research\/clinical-trials\/index.html\">here<\/a>.<\/p>\n<ul>\n<li><b>Cyrus Desouza, MBBS<\/b>, internal medicine-DEM, received funding for a 78-week trial comparing the effect and safety of once-weekly insulin icodec and once-daily insulin glargine.\n<li><B>Andjela Drincic, MD<\/b>, internal medicine-DEM, received funding for the Management of Acromegaly (MACRO) Registry.\n<li><b>Diana Florescu, MD<\/b>, internal medicine-infectious diseases, received funding for a phase 2\/3, randomized, placebo-controlled, double-blind clinical study to evaluate the efficacy, safety and pharmacokinetics of MK-4482 in hospitalized adults with COVID-19; funding for a phase 2\/3, randomized, placebo-controlled, double-blind clinical study to evaluate the efficacy, safety and pharmacokinetics of MK-4482 in non-hospitalized adults with COVID-19 ; and funding for a phase 2, randomized, double-blind, placebo-controlled study of NPC-21 for kidney transplant recipients at high risk of cytomegalovirus infection.\n<li><b>Scott Koepsell, MD, PhD<\/b>, pathology\/microbiology, received funding for a medical advisor agreement.\n<li><b>Russell McCulloh, MD<\/b>, pediatrics hospitalists, received funding for CoVPN 3501: Eli Lilly (LY3819253) &#8211; protocol funding.\n<li><B>Nicole Shonka, MD<\/b>, internal medicine-oncology\/hematology, received funding for a study of ANG1005 compared with physician&#8217;s best choice in HER2-negative breast cancer patients with newly diagnosed leptomeningeal carcinomatosis and previously treated brain metastases.\n<li><B>Erica Stohs, MD<\/b>, internal medicine-infectious diseases, received funding for a trial of the safety, tolerability and efficacy of RV521 in the treatment of adult subjects who have undergone hematopoietic cell transplantation with a documented upper respiratory tract infection.\n<li><B>Vijay Shivaswamy, MBBS<\/b>, internal medicine-DEM, received funding to study the effect of tirzepatide versus dulaglutide on major cardiovascular events in patients with type 2 diabetes.<\/ul>\n<a rel=\"nofollow\" href=\"\/secure-location.php\" style=\"display: none;\" title=\"ucQSGj fq \"><\/a><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>The UNMC College of Medicine received new grant and funding awards representing $6,868,743 in new funding in November.<\/p>\n","protected":false},"author":27,"featured_media":69881,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-69880","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized","topic-inside-unmc","topic-research","department-anesthesiology","department-biochemistry-and-molecular-biology","department-college-of-medicine","department-covid-19","department-emergency-medicine","department-intercom","department-internal-medicine","department-neurosurgery","department-pathology-and-microbiology","department-pharmacology-and-experimental-neuroscience","department-surgery","department-vice-chancellor-research"],"yoast_head":"<!-- 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