{"id":72096,"date":"2021-10-26T00:00:00","date_gmt":"2021-10-26T05:00:00","guid":{"rendered":"https:\/\/www.unmc.edu\/newsroom\/2021\/10\/26\/ophthalmology-sheds-light-on-covid-19s-effect-on-blood-vessels\/"},"modified":"2021-10-26T00:00:00","modified_gmt":"2021-10-26T05:00:00","slug":"ophthalmology-sheds-light-on-covid-19s-effect-on-blood-vessels","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/newsroom\/2021\/10\/26\/ophthalmology-sheds-light-on-covid-19s-effect-on-blood-vessels\/","title":{"rendered":"Ophthalmology sheds light on COVID-19&#8217;s effect on blood vessels"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\"><p>During the early days of the ongoing COVID-19 pandemic, critical care physicians at Emory University Hospital in Atlanta started seeing that some of the hardest hit and most critically ill COVID-19 patients also had blood spots and &quot;cotton wool&quot; spots in their eyes. Perhaps evidence that the retina was not getting the oxygen it needs?<\/p>\n<p>So, critical care physicians partnered with a team of ophthalmologists, including Steven Yeh, MD, to take a closer look.<\/p>\n<p>Their findings were fascinating. There were cotton wool spots, retinal hemorrhage, even one patient with retinal vascular occlusion, or blockage of a retinal artery.<\/p>\n<p>&quot;Close to 40%,&quot; in the study sample of critically ill COVID-19 patients, Dr. Yeh said, &quot;had some evidence of retinopathy,&quot; or damage to the retina.<\/p>\n<p>The clinician-scientists immediately took note. The eyes are not just the window to the soul &#8211; but, often to the rest of the body, as well.<\/p>\n<p>&quot;The retina is one of the very few structures where you can actually see blood vessel damage,&quot; Dr. Yeh explained.<\/p>\n<p>And in these patients, that type of eye damage was <a href=\"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/09273948.2021.1952278#:~:text=Retinopathy%20in%20severe%20COVID-19%20was%20associated%20with%20greater%20systemic%20disease%20morbidity%20involving%20multiple%20organs.\" style=\"color:#0563c1; text-decoration:underline\">associated with greater systemic disease morbidity involving multiple organs<\/a>.<\/p>\n<p>Dr. Yeh brought this research project with him to UNMC, when he became Stanley Truhlsen Jr. Endowed Chair and Professor in Ophthalmology at the Truhlsen Eye Institute, earlier this year.<\/p>\n<p>The project already was multidisciplinary, employing ophthalmology, critical care medicine, infectious disease specialists and hospital medicine. Now, as <a href=\"https:\/\/www.emory.edu\/home\/index.html\" style=\"color:#0563c1; text-decoration:underline\">Emory University<\/a> and UNMC join forces as they have in other endeavors, &quot;it&rsquo;s a truly multi-institutional collaboration,&quot; Dr. Yeh said.<\/p>\n<p>Dr. Yeh and team recently <a href=\"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/09273948.2021.1952278#:~:text=Retinopathy%20in%20severe%20COVID-19%20was%20associated%20with%20greater%20systemic%20disease%20morbidity%20involving%20multiple%20organs.\" style=\"color:#0563c1; text-decoration:underline\">published their study<\/a> in the journal Ocular Immunology and Inflammation. Dr. Yeh also presented to the Retina Society Annual Meeting.<\/p>\n<p>What does it mean for patients with COVID-19? &nbsp;Retinopathy may offer unique insight into disease pathogenesis in severe COVID-19.<\/p>\n<p>Or, understanding how COVID-19 affects the eye may tell us more about the way this new disease works, particularly its effect on blood vessels. While we don&rsquo;t understand this process for certain, there are good clues to follow-up on.<\/p>\n<p>&quot;Is this something we need to continue to think about and understand?&quot; Dr. Yeh said. &quot;I&rsquo;m biased as an ophthalmologist but there are a number of disease states such as HIV and diabetes where the findings in the eye inform us about the systemic condition, and vice versa.&quot;<\/p>\n<p><span style=\"color:#323130\">The study was funded in part by Emory&rsquo;s Woodruff Health Sciences Center <a href=\"https:\/\/news.emory.edu\/stories\/2020\/09\/whsc_synergy_awards_2020\/index.html\" style=\"color:#0563c1; text-decoration:underline\">Synergy Award, which supports inter-disciplinary research projects.<\/a><\/span><\/p>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Steven Yeh, MD, and team recently published a study in the journal Ocular Immunology and Inflammation.<\/p>\n","protected":false},"author":27,"featured_media":70695,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-72096","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized","department-covid-19","department-unmc-today-todays-headlines","author_override-kalani-simpson-strategic-communications"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ 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