{"id":72966,"date":"2022-03-02T00:00:00","date_gmt":"2022-03-02T06:00:00","guid":{"rendered":"https:\/\/www.unmc.edu\/newsroom\/2022\/03\/02\/research-highlights-90\/"},"modified":"2022-08-29T14:21:40","modified_gmt":"2022-08-29T19:21:40","slug":"research-highlights-90","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/newsroom\/2022\/03\/02\/research-highlights-90\/","title":{"rendered":"Research highlights"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\"><p><span style=\"color:black\">The UNMC College of Medicine received grant&nbsp;and funding awards representing $7,658,400 in new funding in January.<\/span><\/p>\n<p><b><span style=\"color:black\">Xinglong Wang, PhD,<\/span><\/b><span style=\"color:black\">&nbsp;pharmacology and experimental neuroscience, received a grant of $2,886,632 from DHHS\/NIH\/NIA for a study on FAM222A and amyloid plaque deposition in Alzheimer&#39;s disease.<\/span><\/p>\n<p><b><span style=\"color:black\">Andrew Vasey, MD,<\/span><\/b><span style=\"color:black\"> internal medicine-general medicine, receive a grant of $821,490 from West Virginia University for the RECOVER initiative adult cohort<\/span>.<\/p>\n<p><b><span style=\"color:black\">Lie Gao, MD, PhD,<\/span><\/b><span style=\"color:black\"> anesthesiology, received a grant of $517,639 from DHHS\/NIH\/NHLBI for a study on skeletal muscle Nrf2: Exercise-induced cardiovascular protection<\/span>.<\/p>\n<p><b><span style=\"color:black\">Caroline Ng, PhD,<\/span><\/b><span style=\"color:black\"> pathology\/microbiology, received a grant of $308,979 from the U.S. Department of Defense for a study elucidating the malaria unfolded protein response<\/span>.<\/p>\n<p><b><span style=\"color:black\">Kelly Stauch, PhD,<\/span><\/b><span style=\"color:black\"> neurological sciences, received a grant of $219,409 from the Michael J. Fox Foundation for a study elucidating cell type-specific PINK1 and PRKN expression in vivo.<\/span><\/p>\n<p><b><span style=\"color:black\">Shanna Ratnesar-Shumate, PhD,<\/span><\/b><span style=\"color:black\"> pathology\/microbiology, received a grant of $150,377 from the National Strategic Research Institute for UNMC support to NSRI for preliminary DARPA IV &amp; V planning<\/span>.<\/p>\n<p><b><span style=\"color:black\">Rajendra Angara, PhD,<\/span><\/b><span style=\"color:black\"> pathology\/microbiology, received a grant of $145,020 from the American Heart Association for a study of coxiella-mediated regulation of lipid droplet metabolism in Q fever endocarditis<\/span>.<\/p>\n<p><b><span style=\"color:black\">Susan Swindells, MBBS,<\/span><\/b><span style=\"color:black\"> internal medicine-infectious diseases, received a grant of $110,820 from Boys Town National Research Hospital for multimodal Imaging of neuroHIV dynamics (MIND): An Omaha-Pittsburgh consortium<\/span>.<\/p>\n<p><b><span style=\"color:black\">Roslyn Mannon, MD,<\/span><\/b><span style=\"color:black\"> internal medicine-nephrology, received a grant of $58,652 from the University of California-San Francisco for a study on applying precision medicine to optimize desensitization with noveL biologics or cellular therapies in highly sensitized kidney transplant patients<\/span>.<\/p>\n<p><b><span style=\"color:black\">Tate Johnson, MD,<\/span><\/b><span style=\"color:black\"> internal medicine-rheumatology, received a grant of $50,000 from the Rheumatology Research Foundation for a study of immune and inflammatory mediators of heart failure incidence and severity in rheumatoid arthritis<\/span>.<\/p>\n<p><b><span style=\"color:black\">Tyler Kambis,<\/span><\/b><span style=\"color:black\"> genetics, cell biology and anatomy, received a grant of $33,788 from DHHS\/NIH\/NLBI for targeting metabolic remodeling and mitochondrial dysfunction in the diabetic heart<\/span>.<\/p>\n<p><b><span style=\"color:black\">Suhita Ray,<\/span><\/b><span style=\"color:black\"> genetics, cell biology and anatomy, received a grant of $32,036 from the American Heart Association for determining the role of a sterile alpha motif domain protein in stress-induced signaling and survival<\/span>.<\/p>\n<p><b><span style=\"color:black\">Kajal Kamra,<\/span><\/b><span style=\"color:black\"> anesthesiology, received a grant of $32,036 from the American Heart Association for a study of a novel mechanism of neural control of breathing in acute lung injury<\/span>.<\/p>\n<p><b><span style=\"color:black\">Wallace Thoreson, PhD,<\/span><\/b><span style=\"color:black\"> ophthalmology and visual sciences, received a grant of $18,754 from Creighton University for the Translational Hearing Center.<\/span><\/p>\n<p><b><span style=\"color:black\">Joseph Americo Fernandes, MD,<\/span><\/b><span style=\"color:black\"> neurological sciences, received a grant of $13,452 from Massachusetts General Hospital for a task order.<\/span><\/p>\n<p><b><span style=\"color:black\">Donald Coulter, MD,<\/span><\/b><span style=\"color:black\">&nbsp;pediatrics-oncology\/hematology, received a grant of $2,000 from Children&rsquo;s Hospital of Pennsylvania for work order on larotrectinib for previously untreated NTRK-fusion positive pediatric solid tumors and NTRK-fusion positive relapsd pediatric acute leukemias<\/span>.<\/p>\n<p><b><span style=\"color:black\">Industry-sponsored grants and contracts:<\/span><\/b><\/p>\n<p><span style=\"color:black\">The following industry-sponsored contracts and foundation grants were received.<\/span><\/p>\n<p><b><span style=\"color:black\">Bradford Brabec, MD<\/span><\/b><span style=\"color:black\">, pediatrics administration, received funding for studies of infant formula and toddler drink feeding interventions.<\/span><\/p>\n<p><b><span style=\"color:black\">Diana Florescu, MD,<\/span><\/b><span style=\"color:black\">&nbsp;internal medicine-infectious diseases, received funding for a study of the safety, tolerability and effectiveness of adoptively transferred Viralym-M multivirus-specific T-cells in kidney transplant.<\/span><\/p>\n<p><b><span style=\"color:black\">Matthew Lunning, DO,<\/span><\/b><span style=\"color:black\"> internal medicine-oncology\/hematology, received funding to evaluate the safety and efficacy of genetically engineered autologous cells expressing anti-CD20 and anti-CD19 specific chimeric antigen receptor<\/span>.<\/p>\n<p><b><span style=\"color:black\">Alissa Marr, MD,<\/span><\/b><span style=\"color:black\"> internal medicine-oncology\/hematology, received funding to evaluate enfortumab vedotin in subjects with previously lreated locally advanced or metastatic malignant solid tumors<\/span>.<\/p>\n<p><b><span style=\"color:black\">Nicole Shonka, MD,<\/span><\/b><span style=\"color:black\"> internal medicine-oncology\/hematology, received funding for a study of the efficacy, safety, and pharmacokinetics of intravenously infused berubicin in adult patients with recurrent glioblastoma multiforme<\/span>.<\/p>\n<p><b><span style=\"color:black\">Jill Poole, MD,<\/span><\/b><span style=\"color:black\"> internal medicine-allergy\/immunology, received funding for a study assessing exaceration rate, additional measures of ashma control and safety in adult and adolescent severe asthmatic paricipants.<\/span><\/p>\n<p><b><span style=\"color:black\">Jingwei Xie, PhD,<\/span><\/b><span style=\"color:black\"> surgery-transplant, received funding for exploring electrospun nerve conduit and expanded electrospun nerve grafts<\/span>.<\/p>\n<p><b><span style=\"color:black\">Zachary Bauman, DO,<\/span><\/b><span style=\"color:black\"> surgery-acute care surgery, received funding for rib and sternal fixation.<\/span><\/p>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>The UNMC College of Medicine received grantand funding awards representing $7,658,400 in new funding in January.<\/p>\n","protected":false},"author":27,"featured_media":71577,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-72966","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized","topic-research","department-anesthesiology","department-college-of-medicine","department-genetics-cell-biology-and-anatomy","department-intercom","department-internal-medicine","department-neurological-sciences","department-ophthalmology-and-visual-sciences","department-pathology-and-microbiology","department-pharmacology-and-experimental-neuroscience","department-surgery"],"yoast_head":"<!-- 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