{"id":73437,"date":"2022-05-02T00:00:00","date_gmt":"2022-05-02T05:00:00","guid":{"rendered":"https:\/\/www.unmc.edu\/newsroom\/2022\/05\/02\/research-highlights-92\/"},"modified":"2022-08-29T14:24:39","modified_gmt":"2022-08-29T19:24:39","slug":"research-highlights-92","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/newsroom\/2022\/05\/02\/research-highlights-92\/","title":{"rendered":"Research highlights"},"content":{"rendered":"<div class=\"panel body-content\"><div class=\"panel__container\"><p>The UNMC College of Medicine received grant&nbsp;and funding awards representing $8,067,023 in new funding in March.<\/p>\n<p><b>Xinglong Wang, PhD, <\/b>pharmacology and experimental neuroscience, received a grant of $1,460,552 from DHHS\/NIH\/NIA to study mitochondrial TDP-43 in Alzheimer&#39;s disease and a grant of $150,000 from the Alzheimer&rsquo;s Association to study TDP-43 liquid-liquid phase separation in Alzheimer&#39;s disease.<\/p>\n<p><b>Russell McCulloh, MD,&nbsp;<\/b>pediatrics-hospitalists, received a grant of $698,396 from the Arkansas Children&rsquo;s Hospital Research Institute for the RECOVER Phase II Pediatric Cohort.<\/p>\n<p><b>Derrick Samuelson, PhD,<\/b> internal medicine-pulmonary, received a grant of $693,330 from DHHS\/NIH\/NIDDK to study gut bacterial metallophores in the development and severity of inflammatory bowel disease.<\/p>\n<p><b>Larisa Poluektova, MD, PhD,<\/b> pharmacology and experimental neuroscience, received a grant of $610,497 from DHHS\/NIH\/NIAID to study a new generation of long-acting nucleotides and immune stimulant for treatment of chronic hepatitis B.<\/p>\n<p><b>Tammy Kielian, PhD,<\/b> pathology and microbiology, received a a grant of $580,182 from the DHHS\/NIH\/NIAID to study how T cell-innate immune crosstalk regulates Staphylococcus aureus craniotomy infection.<\/p>\n<p><b>Shanna Ratnesar-Shumate, PhD,<\/b> pathology and microbiology, received a grant of $380,955 from the Battelle Memorial Institute to study the potential for accidental laboratory exposure to biohazards.<\/p>\n<p><b>Ellen Kerns, PhD,<\/b> pediatrics-child health, received a grant of $342,249 from the University of Arkansas for Medical Sciences for the Data Coordinating and Operations Center for the ECHO IDeA States Pediatric Clinical Trials Network.<\/p>\n<p><b>Paul Fey, PhD,<\/b> pathology and microbiology, received a grant of $282,393 from DHHS\/NIH\/NIAID to study mechanisms of staphylococcal skin colonization.<\/p>\n<p><b>Jana Broadhurst, MD, PhD,<\/b>&nbsp;pathology and microbiology, received a grant of $165,401 from Rush University Medical Center for &quot;Preserving Cognitive Resilience: A Biracial Parent-Offspring Study.&quot;<\/p>\n<p><b>Maegen Wallace, MD,<\/b> orthopaedic surgery, received a grant of $90,066 from the Baylor College of Medicine for the Brittle Bone Disorders Consortium of the Rare Disease Clinical Research Network.<\/p>\n<p><b>Ashley Deschamp, MD,<\/b> pediatrics-pulmonary, received a grant of $86,496 from University of Arkansas for Medical Sciences for the Data Coordinating and Operations Center for the ECHO IDeA States Pediatric Clinical Trials Network.<\/p>\n<p><b>Geoffrey Thiele, PhD,<\/b> internal medicine-rheumatology, received a grant of $60,000 from the Rheumatology Research Foundation to study how citrullinated and malondialdehyde-acetaldehyde modified proteins promote cellular and immune responses associated with rheumatoid arthritis.<\/p>\n<p><b>Aaron Barksdale, MD,<\/b> emergency medicine, received a grant of $44,575 from the University of Michigan for a trial of the influence of cooling duration of efficacy in cardiac arrest patients.<\/p>\n<p><b>Jeffrey Cooper, MD,<\/b> emergency medicine, received a grant of $42,000 from the University of Michigan for a hyperbaric oxygen brain injury treatment trial.<\/p>\n<p><b>Amar Singh, PhD,<\/b> biochemistry and molecular biology, received a grant of $30,150 from South Dakota State University for a study on a strategy for safe colon-targeted local therapy of inflammatory bowel disease.<\/p>\n<p><b>Industry-sponsored grants and contracts:<\/b><\/p>\n<p>The following industry-sponsored contracts and foundation grants were received.<\/p>\n<p><b>Benjamin Tepley, MD,<\/b> pediatrics-hospitalists, received funding for a study of PSCA-specific chimeric antigen receptor engineered T-cells in subjects with previously treated advance solid tumors.<\/p>\n<p><b>Kenneth Bayles, PhD,<\/b> pathology and microbiology, received funding to study biosurveillance research.<\/p>\n<p><b>Daniel Surdell, MD,<\/b> neurosurgery, received funding for the SQUID trial for the embolization of the middle meningeal artery (STEM) for treatment of chronic subdural hematoma.<\/p>\n<p><b>Shaheed Merani, MD, PhD,<\/b> surgery-transplant, received funding for a clinical trial to compare the safety and effectiveness of the VitaSmart System with static cold.<\/p>\n<p><b>Jeffrey Delaney, MD,<\/b> pediatrics-cardiology, received funding for a Harmony TPV post-approval study.<\/p>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>The UNMC College of Medicine received grantand funding awards representing more than $8 million in new funding in 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