{"id":78304,"date":"2022-08-02T00:00:00","date_gmt":"2022-08-02T05:00:00","guid":{"rendered":"https:\/\/www.unmc.edu\/newsroom\/2022\/08\/02\/research-highlights-95\/"},"modified":"2022-08-31T07:56:14","modified_gmt":"2022-08-31T12:56:14","slug":"research-highlights-95","status":"publish","type":"post","link":"https:\/\/www.unmc.edu\/newsroom\/2022\/08\/02\/research-highlights-95\/","title":{"rendered":"Research highlights"},"content":{"rendered":"

The UNMC College of Medicine received grant and funding awards representing more than $10 million in new funding in June.<\/p>\n

Jana Broadhurst, MD, PhD,<\/b> pathology\/microbiology, received a grant of $2,500,000 from DHHS\/CDC for a study on strengthening health care infection prevention and control and improving patient safety in the United States.<\/p>\n

Iqbal Javeed, PhD,<\/b> pathology\/microbiology, received a grant of $1,060,4671 from the U.S. Army\/USAMRAA\/CDMRP to study genomic biomarker driven treatment strategy in PTCL.<\/p>\n

Jingwei Xie, PhD,<\/b> surgery-transplant, received a grant of $470,967 from DHHS\/NIH\/NIDCR for a study of biomimetic and injectable highly porous nanofiber microsphere-based platform for alveolar bone regeneration.<\/p>\n

Yulong Li, MD, PhD,<\/b> emergency medicine, received a grant of $376,075 from DHHS\/NIH to study the neuromuscular junction as a therapeutic target to improve post-traumatic outcomes.<\/p>\n

Gargi Ghosal, PhD,<\/b> genetics, cell biology and anatomy, received a grant of $314,675 from DHHS\/NIH to study regulation of SPRTN protease and SPRTN-mediated DNA-protein crosslink repair.<\/p>\n

Stephen Obaro, MD, PhD,<\/b> pediatrics-infectious diseases, received a grant of $269,172 from Redeemer’s University to study Combatting AntiMicrobial Resistance in Africa (CAMRA) using data science.<\/p>\n

Scot Ouellette, PhD,<\/b> pathology\/microbiology, received a grant of $251,179 from DHHS\/NIH\/NIAD to study functional analysis of the Clp protease systems in chlamydial growth and differentiation.<\/p>\n

Larisa Poluektova, MD, PhD,<\/b> pharmacology\/experimental neuroscience, received a grant of $230,250 from DHHS\/NIH to study enhancement of human immune system development in mouse models.<\/p>\n

Matthew Halanski, MD,<\/b> orthopaedic surgery, received a grant of $214,867 from DHHS\/NIH for knifeless limb lengthening: critical advancement of an innovative therapy.<\/p>\n

Siwei Zhao, PhD,<\/b> surgery-transplant, received a grant of $164,099 from DHHS\/NIH\/NIAMS for a novel high-intensity iontophoresis-based antibiotic delivery device for efficacious eradication of chronic wound biofilms.<\/p>\n

Siddappa Byrareddy, PhD,<\/b> pharmacology\/experimental neuroscience, received a grant of $140,000 from the Wistar Institute for evaluation of a transplant-specific outpatient parenteral antimicrobial therapy (T-OPAT) program: A quasi-experimental study.<\/p>\n

Scott Campbell, PhD,<\/b> pathology\/microbiology, received a grant of $66,837 from West Virginia University for the West Virginia Clinical and Translational Science Institute: Improving health through partnerships and transformative research N3C initiative.<\/p>\n

Gwenn Skar, MD,<\/b> pediatrics-infectious diseases, received a grant of $62,084 from the University of Arkansas for Medical Sciences for a study on improving pediatric COVID-19 vaccine uptake using an mHealth tool: a randomized, controlled trial.<\/p>\n

Sarah Holstein, MD, PhD,<\/b> internal medicine-oncology\/hematology, received a grant of $50,000 from the Nebraska DHHS to study GDPS inhibition in pancreas cancer: effects on chemotherapy resistance.<\/p>\n

Saraswathi Viswanathan, PhD,<\/b> internal medicine-DEM, received a grant of $50,000 from the Nebraska DHHS to study novel metabolic alteration in pancreatic cancer and its implications for therapy.<\/p>\n

Pi-Wan Cheng, PhD,<\/b> biochemistry and molecular biology, received a grant of $50,000 from the Nebraska DHHS to study alcohol-induced sialo-mucin glycans protect cancer cells from immune surveillance.<\/p>\n

Jitu George, PhD,<\/b> OB-GYN, received a grant of $50,000 from the Nebraska DHHS to study PRC1 involvement in pathogenesis of uterine fibroids.<\/p>\n

Armen Petrosyan, PhD,<\/b> biochemistry and molecular biology, received a grant of $50,000 from the Nebraska DHHS to study targeting ER stress as a new therapeutic for advanced prostate cancer.<\/p>\n

Prakash Kshirsagar,<\/b> biochemistry and molecular biology, received a grant of $50,000 from the Nebraska DHHS to study novel microRNA biosensing technology for non-invasive diagnosis of pancreatic cancer.<\/p>\n

Meghana Kesireddy, MBBS,<\/b> internal medicine-oncology\/hematology, received a grant of $50,000 from the American Society of Clinical Oncology to study delineating genetic subtypes and their clinical significance in mantle cell lymphoma.<\/p>\n

Rebecca Slotkowski,<\/b> pediatrics-newborn medicine, received a grant of $40,352 from the DHHS\/NIH for SPARKLED: Social Programming Affects Risk in Kids of Latent Endothelial Disease.<\/p>\n

Afshin Salehi, MD<\/b>, neurosurgery, received a grant of $40,000 from the Edna Ittner Trust Fund UN Foundation to study the design of targeted photosensitizing nanoparticles to enhance laser interstitial thermal therapy against pediatric glioblastoma.<\/p>\n

Steve Gliske, PhD<\/b>, neurosurgery, received a grant of $39,365 from the University of Michigan to characterizing high frequency oscillations as an epilepsy biomarker with big data tools.<\/p>\n

Ashley Deschamp, MD<\/b>, pediatric-pulmonology, received a grant of $16,867 from Creighton University to study genetic markers for susceptibility or resistance to ototoxicity.<\/p>\n

Kusum Kharbanda, PhD<\/b>, internal medicine-GI, received a grant of $15,396 as an IPA for Madan Arumugam — Impaired methylation alters lipid droplet dynamics in liver and adipose tissue: Role in hepatic steatosis.<\/p>\n

Weiwei Zhang, PhD<\/b>, pathology\/microbiology, received a grant of $8,842 from Beckman Research Institute City of Hope genomic subtyping of cutaneous CD30+ lymphoproliferative disorders.<\/p>\n

Ruben Quiros, MD,<\/b> pediatrics-gastroenterology, received a grant of $8,000 from the Hospital for Sick Children for the Global Alagille Alliance Study.<\/p>\n

Jill Beck, MD,<\/b> pediatrics-hematology\/oncology, received funding for the Cancer Therapy Evaluation Program.<\/p>\n

Industry-sponsored grants and contracts:<\/b><\/p>\n

The following industry-sponsored contracts and foundation grants were received.<\/p>\n

Diana Florescu, MD, <\/b>internal medicine-infectious diseases, received funding for a trial to assess clinical efficacy, safety and reactogenicity of the recombinant MVA-BN-RSV vaccine in adults 60 years of age.<\/p>\n

Daniel Murman, MD,<\/b> neurological sciences, received funding for a study to evaluate the efficacy and safety of gantenerumab in participants at risk for or in the early stages of Alzheimer’s disease.<\/p>\n

Shane Tsai, MD,<\/b> internal medicine-cardiovascular, received funding for the Cardiac Rhythm & Heart Failure (CRHF) Product Surveillance Registry (PSR).<\/p>\n

Tammy Wichmann, MD,<\/b> internal medicine-pulmonary, received funding for a study to evaluate the effects of sotatercept when added to background pulmonary arterial hypertension (PAH) therapy for the  treatment of PAH (SOTERIA).<\/p>\n

Erica Strohs,<\/b> internal medicine-infectious diseases, received funding for evaluation of a transplant-specific outpatient parenteral antimicrobial therapy (T-OPAT) program: A quasi-experimental study.<\/p>\n

James Harper, MD,<\/b> pediatrics-hematology\/oncology, received funding for a study to investigate efficacy and safety of NNC0365-3769 (Mim8) in adults and adolescents with haemophilia A with or without inhibitors.<\/p>\n

Hani Haider, PhD,<\/b> orthopaedic surgery, received funding for a work order: An in vitro<\/i> durability study on the patellar components from a total knee replacement system.<\/p>\n

Kelsey Klute, MD,<\/b> internal medicine-oncology-hematology, received funding for a PRECEDE Consortium site payment.<\/p>\n

Dr. Broadhurst<\/b> received funding for CareCubes validation.<\/p>\n<\/a><\/div><\/div>","protected":false},"excerpt":{"rendered":"

The UNMC College of Medicine received grantand funding awards representing more than $10 million in new funding in 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