Alyssa C. Bouska, PhD

Department Affiliations
Senior Scientist, Iqbal Lab

Education and Training
BS (magna cum laude), Biology, Creighton University, Omaha, NE, 2002
PhD, Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, 2008 

Honors and Awards
Presidential Scholarship, Creighton University, 1999-2002
National Society of Collegiate Scholars, 2000
Program of Excellence Graduate Assistantship, 2005-2008
3rd place, Midwest Scienfitic Biomedial Research Forum (MSBRF), Graduate Student/Resident poster presentation, 2006
4th place, UNMC student poster presentation, MSBRF, 2006
Pathology and Microbiology Award for UNMC students at MSBRF, 2006
Ruth L. Kirschstein National Research Service Award, 2010-2011
American Society of Hematology Abstract Achievement Award, 2012

Notable Publications
Wang C., McKeithan T.W., Gong Q., Zhang W., Bouska A., Rosenwald A., Gascoyne R.D., Wu X., Wang J., Muhammad Z., Jiang B., Rohr J., Cannon A., Steidl C., Fu K., Li Y., Hung S., Weisenburger D.D., Greiner T.C., Smith L., Ott G., Rogan E.G., Staudt L.M., Vose J., Iqbal J., Chan W.C. IDH2R172 mutations define a unique subgroup of patients with angioimmunoblastic T-cell lymphoma. Blood. 2015 Oct 8;126(15):1741-52.

Rohr, J., Guo, S., Huo, J., Bouska, A., Lachel, C., et al. Recurrent activating mutations of CD28 in peripheral T-cell lymphomas, Leukemia. epublication Dec 31, 2015.

Iqbal J., Naushad H., Bi C., Yu J., Bouska A., Rohr J., Chao W., Fu K., Chan W.C., Vose J.M. Genomic signatures in B-cell lymphoma: How can these improve precision in diagnosis and inform prognosis? Blood Rev. 2015 Aug 18.

Iqbal J., Wilcox R., Naushad H., Rohr J., Heavican T.B., Wang C., Bouska A., Fu K., Chan W.C., Vose J.M..Genomic signatures in T-cell lymphoma: How can these improve precision in diagnosis and inform prognosis? Blood Rev. 2015 Aug 18.

Bouska, A.*, Zhang,W*., Gong, Q*, Iqbal,J., et al. Combined copy number and mutation analysis identifies pathways associated with transformation of follicular lymphoma, Leukemia, 2016.

Bouska, A.*, Bi, C.*, Lone, W.*, Zhang W., et. al. Adult High Grade B-cell Lymphoma with Burkitt Lymphoma Signature: Genomic features and Potential Therapeutic Targets. Blood. 2017.

Umakanthan JM, Iqbal J, Batlevi CL, Bouska A, Smith LM, Shostrom V, Nutsch H, William BM, Gregory Bociek R, Lunning M, Bierman P, Younes A, Armitage JO, Vose JM. Phase I/II study of dasatinib and exploratory genomic analysis in relapsed or refractory non-Hodgkin lymphoma. Br J Haematol. 2019 Mar;184(5):744-752. PubMed PMID: 30520026.

Heavican TB*, Bouska A*, Yu J, Lone W, Genetic drivers of oncogenic pathways in molecular subgroups of peripheral T-cell lymphoma. Blood. 2019 Apr 11;133(15):1664-1676. doi:10.1182/blood-2018-09-872549. PubMed PMID: 30782609.

Jain N, Hartert K, Tadros S, Fiskus W, Havranek O, Ma MCJ, Bouska A, Heavican T, Kumar D, Deng Q, Moore D, Pak C, Liu CL, Gentles AJ, Hartmann E, Kridel R, Smedby KE, Juliusson G, Rosenquist R, Gascoyne RD, Rosenwald A, Giancotti F, Neelapu SS, Westin J, Vose JM, Lunning MA, Greiner T, Rodig S, Iqbal J, Alizadeh  AA, Davis RE, Bhalla K, Green MR. Targetable genetic alterations of TCF4 (E2-2) drive immunoglobulin expression in diffuse large B cell lymphoma. Sci Transl Med. 2019 Jun 19;11(497). PubMed PMID: 31217338.

Abdalhamid B, Mccutchen EL, Bouska AC, Weiwei Z, Loeck B, Hinrichs SH, Iwen PC. Whole genome sequencing to characterize shiga toxin-producing Escherichia coli O26 in a public health setting. J Infect Public Health. 2019 Jun 19. PubMed PMID: 31229413.
Book Chapters 
Alyssa Bouska, SharathKumar Bagvati, Javeed Iqbal, Basem M. William, and Wing C. Chan. Chapter 2. Follicular Lymphoma: Recent Advances. From: Hematologic Cancers: From Molecular Pathobiology to Targeted Therapeutics. Cancer Growth and Progression, Vol. 14. Tao, Jianguo; Sotomayor, Eduardo (Eds.).  November 13, 2012.