Sugandha Saxena, PhD

Department Affiliations
Postdoctoral Trainee, Singh Lab

Education and Training
BTech, University School of Biotechnology, Indraprastha University, New Delhi, India, 2010
MTech, University School of Biotechnology, Indraprastha University, New Delhi, India, 2012
PhD, Biochemistry & Molecular Biology, University of Nebraska Medical Center, Omaha, NE, 2017 

Honors and Awards
Graduate Fellowship, University of Nebraska Medical Center, Omaha, NE, 2017
Graduate Assistantship, University of Nebraska Medical Center, Omaha, NE, 2016

Notable Publications
Wu L., Saxena S., and Singh R.K..  “Neutrophils in the tumor microenvironment”.  In. The Tumor Microenvironment-Novel concepts: Advances in Experimental Medicine and Biology.  Editor: Alexander Birbrair, in press. Springer Nature, 2019. (Book Chapter)

Wu, L.; Saxena, S.; Awaji, M.; Singh, R.K. Tumor-Associated Neutrophils in Cancer: Going Pro. Cancers 2019, 11, 564.

Sharma B.*, Nannuru K.C.*, Saxena S.*, Varney M.L., Singh R.K.. CXCR2: A Novel Mediator of Mammary Tumor Bone Metastasis. Int J Mol Sci. 2019 Mar 12;20(5) (* authors have contributed equally to the work).

Saxena S., Purohit A., Varney M.L., Hayashi Y., Singh R.K.. Semaphorin-5A maintains epithelial phenotype of malignant pancreatic cancer cells. BMC Cancer. 2018 Dec 22;18(1):1283.

Saxena S., Hayashi Y., Wu L., Awaji M., Atri P., Varney M.L., Purohit A., Rachagani S., Batra S.K., Singh R.K.. Pathological and functional significance of Semaphorin-5A in pancreatic cancer progression and metastasis. Oncotarget. 2017 Dec 23;9(5):5931-5943.

Wu S.*, Saxena S.*, Varney M.L., Singh R.K. CXCR1/2 Chemokine Network Regulates Melanoma Resistance to Chemotherapies Mediated by NF-κB. Curr Mol Med. 2017;17(6):436-449. (* authors have contributed equally to the work).

Sharma B., Varney M.L., Saxena S., Wu L., Singh R.K. Induction of CXCR2 ligands, stem cell-like phenotype, and metastasis in chemotherapy-resistant breast cancer cells. Cancer Lett. 2016 Mar 28;372(2):192-200.

Cai B., Giridharan S.S., Zhang J., Saxena S., Bahl K., Schmidt J.A., Sorgen P.L., Guo W., Naslavsky N., Caplan S. Differential roles of C-terminal Eps15 homology domain proteins as vesiculators and tubulators of recycling endosomes. J Biol Chem. 2013 Oct 18;288 (42):30172-80. .