Nora M. Chapman, Ph.D.

Department Affiliations
Emeritus Faculty

Virology, Molecular biology

Education and Training
B.A. (Highest Honors), University of California, Santa Cruz, 1975
Ph.D., Harvard University, Cambridge, MA, 1981

Teaching Activities
Graduate Students:
Supervisory committee for two M.S. students
Member, Departmental Graduate Committee

National Activities
American Society for Virology
American Society of Microbiology
American Association for the Advancement of Science
Association for Women in Science
Association of University Women

Notable Publications
"COMPLETE REVERSION OF A MULTIPLY MUTATED COXSACKIEVIRUS B3 (CVB3) CRE(2C) DURING REPLICATION OF 5’ TERMINALLY DELETED VIRUS".  Oral presentation. European Picornavirus Organization (EUROPIC) Congress, Les Diablerets, Switzerland.  September 4-8, 2016.

Smithee S, Tracy S, Chapman NM. Mutational disruption of the CRE(2C) in coxsackievirus B3 leads to 5’ terminal genomic deletions. J. Virol. 2015 September 9. doi:10.1128/JVI.01308-15. [Epub ahead of print]

Chapman NM, Coppieters K, von Herrath M, Tracy S. The microbiology of human hygiene and its impact on type 1 diabetes. Islets. 2012 Jul-Aug;4(4):253-61. doi: 10.4161/isl.21570. Epub 2012 Jul 1. PMCID:PMC3496651

Sharma N, Ogram SA, Morasco BJ, Spear A, Chapman NM, Flanegan JB. (2009) Functional role of the 5’ terminal cloverleaf in coxsackievirus RNA replication. Virology 393:238-49).

Chapman NM, Kim KS, Drescher KM, Oka K, Tracy S. (2008) 5' terminal deletions in the genome of a coxsackievirus B2 strain occurred naturally in human heart. Virology. 375:480-91.

Chapman NM, Kim KS. (2008) Persistent coxsackievirus infection: enterovirus persistence in chronic myocarditis and dilated cardiomyopathy. Curr Top Microbiol Immunol. 2008;323:275-292.

Kim KS, Chapman NM, Tracy S. Replication of coxsackievirus B3 in primary cell cultures generates novel viral genomic deletions. J Virol. 2007 82: 2033-2037.

Carson SD, Kim KS, Pirruccello SJ, Tracy S, Chapman NM. Endogenous low-level expression of the coxsackievirus and adenovirus receptor enables coxsackievirus B3 infection of RD cells. J Gen Virol. 2007 88:3031-8.

Kanno T, Kim K, Kono K, Drescher KM, Chapman NM, Tracy S. (2006) Group B coxsackievirus diabetogenic phenotype correlates with replication efficiency. J Virol. 2006 80:5637-5643.

Tracy S, Chapman NM, Drescher KM, Kono K, Tapprich W. (2006) Evolution of virulence in picornaviruses. Curr Top Microbiol Immunol. 2006;299:193-209.

Kim K-S, Tracy S, Tapprich W, Bailey J, Lee C-K, Kim K, Barry WH, Chapman NM (2005) 5' Terminal Deletions Occur in Coxsackievirus B3 During Replication in Murine Hearts and Cardiac Myocyte Cultures and Correlate with Encapsidation of Negative-Strand Viral RNA. J Virol. 79:7024-7041.

Lee C-K, Kono K, Haas E, Kim K-S, Drescher K, Chapman NM, Tracy S. (2005) Characterization of an infectious cDNA copy of the genome of a naturally-occurring, avirulent CVB3 clinical isolate. J Gen Virol. 86:197-210.

Cunningham KA, Chapman NM, Carson SD (2003) Caspase-3 activation and ERK phosphorylation during CVB3 infection of cells: influence of the coxsackievirus and adenovirus receptor and engineered variants. Virus Res 92:179-186.

For a detailed list of publications, click here.