Chengfeng Bi, M.D., Ph.D.

Department Affiliations
Instructor

Interests
Hematopathology, lymphoma research

Education and Training
M.D., Sichuan University, Sichuan, China, 1999-2004
M.S., Sichuan University, Sichuan, China, 2004-2007
Ph.D., Sichuan University, China & University of Nebraska Medical Center, US, 2008-2012
Postdoctoral Research Associate, Dept. of Pathology and Microbiology, University of Nebraska Medical Center, US, 2012- 2015
Senior Research Associate, Dept. of Pathology and Microbiology, University of Nebraska Medical Center, US, 2015- 2017

Notable publications
Bi C, Zhang X, Lu T, Zhang X, Wang X, Meng B, Zhang H, Wang P, Vose JM, Chan WC, McKeithan TW, Fu K. Inhibition of 4EBP phosphorylation mediates the cytotoxic effect of mechanistic target of rapamycin kinase inhibitors in aggressive B-cell lymphomas. Haematologica 2017 Apr; 102(4): 755-764.

Bouska A*, Bi C*, Lone W*, Zhang W, Kedwaii A, Heavican T, Lachel CM, Yu J, Ferro R, Eldorghamy N, Greiner TC, Vose J, Weisenburger DD, Gascoyne RD, Rosenwald A, Ott G, Campo E, Rimsza LM, Jaffe ES, Braziel RM, Siebert R, Miles RR, Dave S, Reddy A, Delabie J, Staudt LM, Song JY, McKeithan TW, Fu K, Green M, Chan WC, Iqbal J.  Adult high-grade B-cell lymphoma with Burkitt lymphoma signature: genomic features and potential therapeutic targets. Blood 2017 Oct 19; 130(16): 1819-1831.

Tian T*, Bi C*, Hein AL, Zhang X, Wang C, Shen S, Yuan J, Greiner TC, Enke C, Vose JM, Yan Y, and Fu K. Rac1 is a Novel Therapeutic Target in Mantle Cell Lymphoma. Blood Cancer J. 2018.

Bi CF, Tang Y, Zhang WY, Zhao S, Wang XQ, Yang QP, Li GD, Liu WP. Sporadic Burkitt lymphomas of children and adolescents: a retrospective study of 43 patients from South-West China in clinicopathology, immunophenotype and genotype. Diagn Pathol. 2012 Jun 22;7:72.

Huang X, Shen Y, Liu M, Bi C, Jiang C, Iqbal J, and Fu K. Quantitative proteomics reveals that miR-155 regulates the PI3K-AKT pathway in diffuse large B-cell lymphoma. Am J Pathol 2012 Jul; 181(1): 26-33.

 Li X, Huang Y, Bi C, Yuan J, He H, Zhang H, et al. Primary central nervous system diffuse large B-cell lymphoma shows an activated B-cell-like phenotype with co-expression of C-MYC, BCL-2, and BCL-6. Pathol Res Pract 2017 Jun; 213(6): 659-665. 

Zhao X, Lwin T, Silva A, Shah B, Tao J, Fang B, Zhang L, Fu K, Bi C, Li J, Jiang H, Meads MB, Jacobson T, Silva M, Distler A, Darville L, Zhang L, Han Y, Rebatchouk D, Di Liberto M, Moscinski LC, Koomen JM, Dalton WS, Shain KH, Wang M, Sotomayor E, Tao J. Unification of de novo and acquired ibrutinib resistance in mantle cell lymphoma. Nat Commun 2017 Apr 18; 8: 14920.

Huang X, Meng B, Iqbal J, Ding BB, Perry AM, Cao W, Smith LM, Bi C, Jiang C, Greiner TC, Weisenburger DD, Rimsza L, Rosenwald A, Ott G, Delabie J, Campo E, Braziel RM, Gascoyne RD, Cook JR, Tubbs RR, Jaffe ES, Armitage JO, Vose JM, Staudt LM, McKeithan TW, Chan WC, Ye BH, Fu K. Activation of the STAT3 signaling pathway is associated with poor survival in diffuse large B-cell lymphoma treated with R-CHOP. J Clin Oncol. 2013;31(36):4520-8.

For a detailed list of publications, click here.