Steven D. Carson, PhD

Department Affiliations

Coxsackievirus, Adenovirus cell surface Receptor (CAR), Blood Coagulation (tissue factor), Cell Membranes, Protein Chemistry
Please see Dr. Carson's lab for details on his current research, as well as his work with the Enterovirus Research Group.

Education and Training
BA, Rice University, 1973
PhD, University of Texas Graduate School of Biomedical Sciences, 1978
NSF, National Needs Postdoctoral Fellow, Yale University School of Medicine, 1978-1979
NIH Individual Research Service Award, Yale University School of Medicine, 1979-1981

Teaching Activities
Medical Students - Lectures on Blood Coagulation, M2 Hematology/Oncology Core
Graduate students - Graduate student supervisor/mentor
PAMM 940 Molecular Basis of Human Disease (with Dr. Maurice Godfrey)

Notable Publications 

Carson SD, Tracy S, Kaczmarek ZG, Alhazmi A, Chapman NM. Three capsid amino acids notably influence coxsackie B3 virus stability. J Gen Virol. 2015 October 20. doi:  10.1099/jgv.0.000319.

Organtini, L. J., A. M. Makhov, J. F. Conway, S. Hafenstein, and S. D. Carson. 2014. Kinetic and structural analysis of coxsackievirus B3 receptor interactions and formation of the A-particle. J. Virol. 88:5755-5765.

 Carson, S. D. 2014. Kinetic models for receptor-catalyzed conversion of coxsackievirus B3 to A-particles. J. Virol. 88:11568-11575.

Carson, S. D., and S. J. Pirruccello. 2013. HeLa cell heterogeneity and Coxsackievirus B3 cytopathic effect: Implications for inter-lab reproducibility of results. J. Med. Virol. 85:677-683.

Carson, S. D., N. M. Chapman, S. Hafenstein, and S. Tracy. 2011. Variation of coxsackievirus B3 capsid primary structure, ligands, and stability are selected in a coxsackievirus and adenovirus receptor-limited environment. J. Virol. 85:3306-3314.

Jacobs, A.C., I. Hood, K.L. Boyd, P.D. Olson, J. Morrison, S. Carson, K. Sayood, P.C. Iwen, E.P. Skaar, P.M. Dunman. 2010. Inactivation of phospholipase D diminishes Acinetobacter baumannii pathogenesis. Infect. Immun. 78:1952-1962.

Balasubramanian, S., N. Babai, A. Chaudhuri, F. Qiu, S. Bhattacharya, B. J. Dave, S. Parameswaran, S.D. Carson, W.B. Thoreson, J.G. Sharp, M. Rao, and I. Ahmad. 2009. Non cell-autonomous reprogramming of adult ocular progenitors: generation of pluripotent stem cells without exogenous transcription factors. Stem Cells 27:3053-3062.

Freimuth, P., L. Philipson, and S.D. Carson. 2008. The coxsackievirus and adenovirus receptor (CAR). Current Topics in Microbiology and Immunology 323:67-87.

Carson, S.D., K.-S. Kim, S. J. Pirruccello, S. Tracy, and N.M. Chapman. 2007. Endogenous low-level expression of the coxsackievirus and adenovirus receptor (CAR) enables coxsackievirus B3 infection of RD cells. J. Gen Virol. 88:3031-3038

Drescher, K.M., K. Kono, S. Bopegamage, S.D. Carson, and S. Tracy. 2004. Coxsackievirus B3 infection and type 1 diabetes development in NOD mice: insulitis determines susceptibility of pancreatic islets to virus infection. Virology 329(2):381-94.

Carson, S.D. 2004. Coxsackievirus and adenovirus receptor (CAR) is modified and shed in membrane vesicles. Biochemistry 43:8136-8142.

Carson, S.D., B.L. Switzer, S.M. Tracy, and N.M. Chapman. 2004. Monoclonal antibody against mouse CAR following genetic immunization. Hybridoma and Hybridomics 23:19-22.

Cunningham, K.A., N.M. Chapman, and S.D. Carson. Caspase-3 activation and ERK phosphorylation during CVB3 infection of cells: Influence of the coxsackievirus and adenovirus receptor and engineered variants. Virus Res. 92:179-186, 2003.

Carson, S.D. and N.M. Chapman. Coxsackievirus and adenovirus receptor (CAR) binds immunoglobulins. Biochemistry 40:14324-14329, 2001.

Dr. Carson's personal website.

For a detailed list of publications, click here.