Rodney D. McComb, M.D.

Department Affiliations
Director, Neuropathology
Director, Electron Microscopy

The Neuropathology clinical service provides diagnostic consultation for brain tumors, neuromuscular diseases, dementia, neurodegenerative diseases, and all surgical or autopsy-derived neuropathology specimens.

Brain Tumors, Muscle and Nerve Pathology, Surgical and Autopsy Neuropathology, Neurodegenerative Disease, Electron Microscopy

Education and Training
B.S., University of Maryland, 1972
M.D., University of Rochester School of Medicine and Dentistry, 1976
Residency, Anatomic Pathology, University of Kentucky Medical Center, 1976-1979
Fellowship, Neuropathology, Duke University Medical Center, 1979-82
Board Certified in Neuropathology and Anatomic Pathology, 1982

Notable Publications
Salem B, Thaisetthawatkul P, Fernandes JA, McComb RD.  Adult-onset acid maltase deficiency with isolated axial muscle involvement.  J Clin Neuromus Dis 2010;12:30-5.

Lutz RE, Dimmock D, Schmitt ES, Zhang Q, Tang LY, Reyes C, Truemper E, McComb RD, Hernandez A, Basinger A, Wong LJC.  De novo mutations in POLG presenting with acute liver failure or encephalopathy.  J Pediatr Gastroenterol Nutr 2009;49:126-9.

Parisi JE, Miller DV, Boyer PJ, Brat DJ, Cochran EJ, Cohen ML, DeMasters BK, Dolinak D, McComb RD, McLendon RE, Powell SZE, Prayson RA, Vinters HV, Yachnis AT.  Protocol for the examination of specimens from patients with tumors of the brain/spinal cord.  Arch Pathol Lab Med 2008;132:907-12.

Hellbusch LC, Robinson MN, McComb RD, Gordon BG, Meyer RC.  Medulloblastoma with extensive nodularity: a report of two cases.  Pediatr Neurosurg 2008;44:430-2.

Pipinos II, Swanson SA, Zhu Z, Nella AA, Weiss DJ, Gutti TL, McComb RD, Baxter BT, Lynch TG, Casale GP.  Chronically ischemic mouse skeletal muscle exhibits myopathy in association with mitochondrial dysfunction and oxidative damage.  Am J Physiol Regul Integr Comp Physiol 2008;295:R290-6.

Markopoulou K, Dickson DW, McComb RD, Wszolek ZK, Katechalidou L, Avery L, Stansbury MS, Chase BA.  Clinical, neuropathological and genotypic variability in SNCA A53T familial Parkinson's disease. Variability in familial Parkinson's disease.  Acta Neuropathol 2008;116:25-35.

Penn RG, Guarner J, Sejvar JJ, Hartman H, McComb RD, Nevins DL, Bhatnagar J, Zaki SR.  Persistent neuroinvasive West Nile virus infection in an immunocompromised patient.  Clin Infect Dis 2006;42:680-3.

Josephs KA, Uchikado H, McComb RD, Bashir R, Wszolek Z, Swanson J, Matsumoto J, Shaw G, Dickson DW.  Extending the clinicopathological spectrum of neurofilament inclusion disease.  Acta Neuropathol (Berl) 2005;109:427-32.

Wszolek ZK, Pfeiffer RF, Tsuboi Y, Uitti RJ, McComb RD, Stoessl AJ, Strongosky AJ, Zimprich A, Muller-Myhsok B, Farrer MJ, Gasser T, Calne DB, Dickson DW.  Autosomal dominant parkinsonism associated with variable synuclein and tau pathology.  Neurology 2004;62:1619-22.

For a detailed list of publications, click here.