Keer Sun, Ph.D.

Department Affiliations
Assistant Professor

Interests
Immunology, the impact of oxidative stress on the complex virus-host-bacterium interaction occurring during influenza and MRSA co-infection.
 
Education and Training
Postdoctoral  trainee, Immunology, Albany Medical College, NY, 2008
Ph. D, Immunology, Albany Medical College, NY,  2006
M.S., Immunology, Albany Medical College, NY, 2004
M.S., Biochemistry, Institute of Basic Medical Science, 1996
B.S., Botany, Lanzhou University, China, 1993  

Notable Publications

Metzger DW, Furuya Y, Salmon SL, Roberts S, Sun K. Limited efficacy of antibacterial vaccination against secondary serotype 3 pneumococcal pneumonia following influenza infection.J Infect Dis. 212(3):445-52, 2015. PMID: 25649173

 Sun K*, Salmon S, Yajjala VK, Bauer C, Metzger DW. Expression of Suppressor of Cytokine Signaling 1 (SOCS1) Impairs viral clearance and exacerbates lung injury during influenza infection. PLoS Pathog. 10(12):e1004560, 2014. PMID: 25500584. (* Corresponding author)

 Sun K*, Metzger DW. Influenza infection suppresses NADPH Oxidase–dependent phagocytic bacterial clearance and enhances susceptibility to secondary methicillin-resistant Staphylococcus aureus infection. J Immunol. 192(7):3301-7, 2014. PMCID: PMC3965630. (*corresponding author)

 Metzger DW, Sun K. Immune dysfunction and bacterial coinfections following Influenza. J Immunol. 191(5):2047-52, 2013. PMCID: PMC3760235

 Sun K*, Gan Y, and Metzger DW. Analysis of murine genetic predisposition to pneumococcal infection reveals a critical role of alveolar macrophages in maintaining the sterility of the lower respiratory tract. Infect Immun. 79(5):1842-7, 2011. (* Corresponding author)

 Sun K, Ye J, Perez DR, and Metzger DW. Seasonal FluMist Vaccination Induces Cross-Reactive T Cell Immunity against H1N1 (2009) Influenza and Secondary Bacterial Infections. J Immunol. 186(2):987-93, 2011.

 Sun K, Torres L, and Metzger DW. A detrimental effect of IL-10 on protective pulmonary humoral immunity during primary influenza A virus infection. J Virol. 84:5007-14, 2010.

 Sun K, and Metzger DW. Inhibition of pulmonary anti-Bacterial defense by IFN-g produced during recovery from influenza virus infection. Nature Med. 14(5):558-564, 2008.

 Sun K, Salmon SL, Lotz SA, and Metzger DW. Interleukin-12 promotes gamma interferon-dependent neutrophil recruitment in the lung and improves protection against respiratory Streptococcus pneumoniae infection. Infect Immun. 75(3):1196-202, 2007.

For a detailed list of publications, click here