Aswath P. Chandrasekar, MBBS

Education

 

July 2021 - June 2025 (expected)

Residency, Department of Pathology and Microbiology, Anatomic and Clinical Pathology,  University of Nebraska Medical Center

2019-2021

Post Doctoral Research Fellow 
HIV/Immunology Laboratory, Mayo Clinic, Rochester, Minnesota, USA

2018-2019

Research Trainee
HIV/Immunology Laboratory, Mayo Clinic, Rochester, Minnesota, USA  

2012-2018

Medical School, Bachelor of Medicine Bachelor of Surgery (MBBS)
K.S. Hegde Medical Academy, Mangalore, Karnataka, India

Honors and Awards 

 

 

MBBS bestowed with “First Class” honors

2015-2016

Founder and co-secretary, KSHEMA Music Club

 

Inaugural member, KSHEMA literary forum

2017-2018

Editor, KSHEMA Interns Manual, 1st Edition

2015-2016

Member, KSHEMA Students Council

Peer Reviewed Publications: 

Natesampillai S, Paim AC, Cummins NW, Chandrasekar AP, Bren GD, Lewin SR, Kiem HP, Badley AD. TRAILshort Protects against CD4 T Cell Death during Acute HIV Infection. J Immunol. 2019 Aug 1;203(3):718-724. doi: 10.4049/jimmunol.1900271. Epub 2019 Jun 12. PMID: 31189571; PMCID: PMC6785036.

Chandrasekar AP, Cummins NW, Badley AD. The Role of the BCL-2 Family of Proteins in HIV-1 Pathogenesis and Persistence. Clin Microbiol Rev. 2019 Oct 30;33(1):e00107-19. doi: 10.1128/CMR.00107-19. PMID: 31666279; PMCID: PMC6822993. 

French AJ, Natesampillai S, Krogman A, Correia C, Peterson KL, Alto A, Chandrasekar AP, Misra A, Li Y, Kaufmann SH, Badley AD, Cummins NW. Reactivating latent HIV with PKC agonists induces resistance to apoptosis and is associated with phosphorylation and activation of BCL2. PLoS Pathog. 2020 Oct 19;16(10):e1008906. doi: 10.1371/journal.ppat.1008906. PMID: 33075109; PMCID: PMC7595626. 

Alto A, Natesampillai S, Chandrasekar AP, Krogman A, Misra A, Shweta F, VanLith C, Yao JD, Cummins NW, Badley AD. The Combination of Venetoclax and Ixazomib Selectively and Efficiently Kills HIV-Infected Cell Lines but Has Unacceptable Toxicity in Primary Cell Models. J Virol. 2021 May 24;95(12):e00138-21. doi: 10.1128/JVI.00138-21. PMID: 33827940.

Chandrasekar AP, Maynes M, Badley AD. The long road to TRAIL therapy: a TRAILshort detour. Oncotarget. 2021 Mar 30;12(7):589-591. doi: 10.18632/oncotarget.27902. PMID: 33868580; PMCID: PMC8021024.

International Conference Presentations and Published Abstracts: 

Aswath P Chandrasekar, Mark Maynes, Sekar Natesampillai, F.N.U. Shweta, Andrew D. Badley, Nathan W. Cummins. “SARS-Cov-2 Spike Protein Induces Monocyte Apoptosis and Interleukin-8 Production”, Conference on Retroviruses and Opportunistic Infections (CROI) 2021 (Virtual conference), Spotlight Presentation, Presenting author.

Aswath P Chandrasekar, Nathan W. Cummins , Sekar Natesampillai , Anisha Misra , Alecia Alto , Andrew D. Badley. “Venetoclax Significantly Reduces HIV Viral Load In Vivo And In Vitro”, Conference on Retroviruses and Opportunistic Infections (CROI) 2021 (Virtual conference), Spotlight Presentation, Presenting author.

Binny Khandakar, Aswath P Chandrasekar, Ashton Krogman, Benjamin VanTreeck, Nathan Cummins, Sekar Natesampillai, Enrique Garcia-Rivera, Mahendra Rathore, Khashayarsha Khazaie, Andrew Badley, Rondell Graham “TRAILshort is a Novel Potential Therapeutic Target in Pancreatic Ductal Adenocarcinoma”, USCAP 2021 (Virtual conference), Co-author.

Teaching and Related Activities: 

Hobbies:
I greatly enjoy scientific rumination, writing and publication.  Music is a very serious passion of mine, I play the guitar and sing, and I enjoy writing original music. I follow European football and tennis religiously and am also an avid reader and love pursuing the random Wikipedia rabbit hole.

Career Interests:
Cellular Therapy, Transfusion Medicine, Microbiology, and associated basic science research.