Ashley Hein, MD

2020-Present Resident, Department of Pathology, Microbiology and Immunology Anatomic and Clinical Pathology Residency, University of Nebraska Medical Center, Omaha, NE
Honors and Awards   
2021 Trainee Award, Association for Pathology Informatics Summit
2021 Society of ’67 Kinney Scholar
2020 Jerald R. Schenken, M.D. Outstanding Achievement in Pathology and Microbiology Award
2019-2020  Dr. E.T. Manning Memorial Scholarship
2017-2018 Dr. John Gilmore Scholarship
2017-2018 James Walter Thomas Medical Scholarship 
2016-2017 Edna Ittner Medical Student Scholarship
2017 Medical Student Summer Research Program Stipend
  Four-year, full-tuition Distinguished Scholarship to Universty of Nebraska at Omaha

Hein AL, Rohr J, & Lele SM. Paraganglioma of the Urinary Bladder: A Case Report and Comprehensive Literature Review. In progress.

Hein AL, Mukherjee M, Cox JL, Santiago-Pintado A, Molani MA, Talmon GA, Hanson CK, Natarajan SK, Van Ormer M, Thompson M, Thoene M, Lyden E, Nordgren T, Akhter A, Anderson-Berry A, & Yuil-Valdes A. QuPath digital immunohistochemical analysis of placental tissue. In progress.

Kanteti A.P., Atiya S, Hein AL, Cox JL, Martinez Duarte E. Medullary Thyroid Carcinoma Presenting as Metastatic Disease to the Breast. Case Rep Pathol. 2020;2020:6138409. Published 2020 May 22. doi:10.1155/2020/6138409

Hein AL & Yuil-Valdes A. Informatics, digital & computational pathology: Education. Pathology Outlines. Published Apr 30 2020.

Hein AL, Brandquist ND, Ouellette CO, Seshacharyulu P, Enke CA, Ouellette MM, Batra SK & Yan Y. PR55α regulatory subunit of PP2A inhibits the MOB1/LATS cascade and stabilized YAP in pancreatic cancer cells. Oncogenesis. 2019, Oct;8(11):63. PMID: 31659153

Tian T, Bi C, Hein AL, Zhang X, Wang C, Shen S, Yuan J, Greiner TC, Enke C, Vose J, Yan Y & Fu K. Rac1 is a novel therapeutic target in mantle cell lymphoma. Blood Cancer J. 2018, Feb;8(2):17. PMID: 29434202

Arnst JL, Hein AL, Taylor MA, Palermo NY, Contreras JI, Sonawane YA, Wahl AO, Ouellette MM, Natarajan A & Yan Y. Discovery and characterization of small molecule Rac1 inhibitors. Oncotarget. 2017, May;8(21):34586–34600. PMID: 28410221.

Hein AL, Post CM, Sheinin YM, Lakshmanan I, Natarajan A, Enke CA, Batra SK, Ouellette MM & Yan Y.  RAC1 GTPase promotes the survival of breast cancer cells in response to hyper-fractionated radiation treatment. Oncogene. 2016, Dec;35(49):6319–6329. PMID: 27181206.

Hein AL, Seshacharyulu P, Rachagani S, Sheinin YM, Ponnusamy MP, Mumby MC, Ouellette MM, Batra SK & Yan Y. PR55α Subunit of Protein Phosphatase 2A Supports the Tumorigenic and Metastatic Potential of Pancreatic Cancer Cells by Sustaining Hyperactive Oncogenic Signaling. Cancer Res. 2016, Apr;76(8):2243–2253. PMID: 26893480.

Yan Y, Hein AL, Greer PM, Wang Z, Kolb RH, Batra SK & Cowan KH. A novel function of HER2/Neu in the activation of G2/M checkpoint in response to γ-irradiation. Oncogene. 2015, Apr;34(17):2215–2226. PMID: 24909175.

Hein AL, Ouellette MM & Yan Y. Radiation-induced signaling pathways that promote cancer cell survival (review). Int J Oncol, 2014, Nov;45(5):1813-1819. PMID: 25174607.

Yan Y, Hein AL, Etekpo A, Burchett KM, Lin C, Enke CA, Batra SK, Cowan KH & Ouellette MM. Inhibition of RAC1 GTPase sensitizes pancreatic cancer cells to γ-irradiation. Oncotarget. 2014, Nov;5(21):10251–10270. PMID: 25344910.

Poster Presentations
Yuil-Valdes A, Mukherjee M, Hein AL, Cox JL, Santiago Pintado A, Molani MA, Talmon GA, Hanson CK, Lyden E, Nordgren T, Akhter A, Anderson-Berry A. Preliminary findings of QuPath digital immunohistochemical analysis of placental tissue. Digital Pathology Association, Visions Conference. Orlando, FL. Oct 6-8, 2019.

Hein AL, Seshacharyulu P, Rachagani S, Sheinin Y, Ouellette MM, Ponnusamy MP, Mumby MC, Batra SK & Yan Y. PP2Aα regulatory subunit PR55 supports the tumorigenic and metastatic potential of pancreatic cancer. UNMC Pancreatic SPORE Retreat. Omaha, NE. Apr 5, 2016

Hobbies and Interests
Cooking, traveling, hiking, gardening, pet ownership, reading novels.