Oversight

Interim Director

 
Howard E. Gendelman

Howard E. Gendelman, MD, is the Margaret R. Larson Professor of Internal Medicine and Infectious Diseases and chair of the UNMC Department of Pharmacology and Experimental Neuroscience and principal investigator of federally granted projects designed to produce successful long-acting nanoformulated antiretroviral drug therapies in the UNMC College of Medicine. Dr. Gendelman's vision for the NNPP is to develop a functional enterprise that will take basic science discoveries and move them rapidly to human use. Specific interests reside in efforts geared towards the eradication of HIV infections and the delivery of drugs to sites of central nervous system injury. As a world-renowned scientist, Dr. Gendelman has extensive expertise in proteomics, immunology, molecular neuroscience, infectious diseases, neurodegenerative disorders, neurophysiology and viral neuropathogenesis.

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Scientific Advisor

Benson Edagwa, PhD

Benson Edagwa, PhD, is an Associate Professor in the UNMC Department of Pharmacology and Experimental Neuroscience. His research focuses on the design, development and evaluation of antiretroviral prodrugs, development of long-acting slow effective release antiretroviral therapy (LASER ART) and their application to testing in cell and small animal based assays. In collaboration with Dr. Gendelman and members of the nanomedicine laboratory at UNMC, Dr. Edagwa has demonstrated that both hydrophilic and hydrophobic therapeutic compounds could be converted into LASER ART. Single administration of LASER ART significantly extends the half-life of therapeutic compounds. LASER ART is developed through novel chemistry strategies coupled with autophagy stimulation to sustain cell and tissue ART depots.

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