2014 CHAIN Colloquium

NeuroAIDS, other neurodegenerative disorders, mental health ­ the role of brain banks2014 CHAIN Colloquium

May 21, 2014

On May 21, 2014, the fourth Chronic HIV Infection and Aging in NeuroAIDS (CHAIN) Center colloquium was held. This meeting continues our series on contemporary issues related to the effects of HIV on the nervous system. This year's the focus was on our knowledge and use of human brain and other nervous system tissue in research.

Experts in brain banking and biomedical research shared the challenges and opportunities in brain and biospecimen banking, research findings resulting from the use of these specimens, and other current exciting aspects of neuroscience and mental health research.

The sessions were recorded, and we are pleased to provide a link where you can view all of the presentations and the concluding panel discussion. We thank the speakers for participating and sharing their knowledge with the research community. (Download the program for speaker bios).


Welcome and Overview
Howard S. Fox, MD, PhD,  University of Nebraska Medical Center

Speakers (in order of presentations):

Susan Morgello, MD, Icahn School of Medicine at Mount Sinai
"Drugs of abuse and HIV: The value of brain banks in highly confounded populations"

Brett Morrison, MD, PhD, Johns Hopkins University, School of Medicine
"Oligodendrocyte Death and Failed Metabolic Support Contribute to Neurodegeneration in ALS"

Tsuneya Ikezu, MD, PhD, Boston University
"Microglia and exosome-mediated dissemination of pathogenic tau protein in Alzheimer’s disease"

Benjamin B. Gelman, MD, PhD, University of Texas Medical Branch
"Investigating neuroAIDS-related neural transmission and neuropharmacology using human brain specimens"

Tony Wilson, PhD, University of Nebraska Medical Center
"Focusing studies of HIV brain tissue using MEG maps of functionally impaired regions"

Eliezer Masliah, MD, University of California, San Diego
"Alterations in CDK5 signaling and therapeutic opportunities for aging and toxicity associated with NeuroAIDS"

Charles Wood, PhD, University of Nebraska, Lincoln
"HIV infected brain banking in sub-Sahara Africa - lessons learned"

William Yong, MD, Jonsson Cancer Center and Brain Research Institute, David Geffen School of Medicine at UCLA
"From brain tumors to dementia - optimizing the procurement, storage, and quality of biobank specimens"

Babu Guda, PhD, University of Nebraska Medical Center
"Fueling neuroscience research using brain bank databases"

Panel Discussion
Howard E. Gendelman, MD, Moderator

Sponsored by:
Chronic HIV infection and Aging in NeuroAIDS (CHAIN) Center - PI, Howard Fox

University of Nebraska Medical Center Development Funds - PI, Shilpa Buch

Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Howard E. Gendelman, MD, Chair (hegendel@unmc.edu)

A special thank you to the National Institute of Mental Health for its support of the CHAIN Center.