The Chronic HIV and Aging in NeuroAIDS (CHAIN) Center (NIH P30MH062261) in collaboration with the NIMH Center Series Web Events is hosting the 8th Annual CHAIN Center Colloquium. The 2021 colloquium is a virtual event due to ongoing COVID-19 pandemic.
The CHAIN Center, a NIMH Centers Program for Research on HIV/AIDS and Mental Health seeks to bring together leaders in the fields to discuss emerging topics, foster new ideas and collaborations, and educate new and established investigators. The talks will be relevant to researchers and clinicians investigating and treating PLWH, with a focus on NeuroHIV.
Chronic HIV and Aging In NeuroAIDS (CHAIN) Center | NIH P30 MH062261
MPI: Drs. Shilpa Buch and Howard Fox
NIMH Center Series Host: Prof. Norman Haughey, PhD
2021 CHAIN Colloquium Speakers
Jonathan Karn, PhD
Reinberger Professor & Chairman, Case Western Reserve University School of Medicine
Role of HIV Latency, Inflammation and Cross-talk Between Microglia & Neurons in NeuroAIDS
May 3rd, 2021 , 12PM ET (11AM CT/9AM PT)
Dr. Karn is an internationally recognized virologist who has made seminal contributions to the study of transcriptional control in HIV. Between 1989 and 1993 Dr. Karn made the important discovery that the HIV regulatory proteins Tat and Rev are RNA binding proteins and demonstrated how this binding activity was essential for their biological activities. The Karn laboratory has established new model systems for studying HIV latency in primary T-cells and demonstrated how epigenetic restrictions are used to silence HIV transcription including the impact of sex hormones on the HIV reservoir. The laboratory also demonstrated latency of HIV in microglial cells and HIV silencing by neurons, work that has been recognized by the Drexel Medicine Outstanding Scientific Achievement Award in Translational Medicine (2016) and the Paradigm Builder Lectureship Award, International Society for NeuroVirology (2016). Dr. Karn has been the Director of the CWRU/UH Center for AIDS Research since 2008. He served as a member of the NIAID Advisory Council and NIAID AIDS Research Advisory Council between 2011 and 2015 and appointed to the NCI Board of Scientific Counselors Basic Sciences for 2015-2020. He was a member of the NIH AMCB study section from 2003 to 2007, serving as Chairman from 2005-2007. He was a member of the ACTG Transformative Science Group (TSG) on HIV Cure strategies (2011-2015) and the Martin Delaney CARE Collaboratory. He was the Executive Editor of the Journal of Molecular Biology from 1989 to 2002 and served multiple terms on the editorial board of Virology. Dr. Karn has mentored 12 graduate students, 38 postdoctoral fellows and 10 research associates since 1980. The laboratory currently has 1 postdoctoral scholar, 2 research associates and 4 research scientists, 3 graduate students, 1 undergraduate student and 1 research assistant. He was elected a Fellow of the American Society of Microbiology in 2011.
Sara Hurtado Bares, MD
Associate Professor, Department of Internal Medicine, University of Nebraska Medical Center (UNMC)
The Impact of the COVID-19 Pandemic on the Mental Health of People With and Without HIV
May 12th, 2021 , 12PM ET (11AM CT/9AM PT)
Dr. Sara Hurtado Bares is an Associate Professor of Internal Medicine in the Division of Infectious Diseases at the University of Nebraska Medical Center. Dr. Bares earned her medical degree from the Icahn School of Medicine at Mount Sinai in New York City and completed her Internal Medicine residency, chief residency and Infectious Diseases fellowship at the University of Chicago. Since joining University of Nebraska Medical Center in 2013, Dr. Bares has been active in patient care, clinical research, and medical education. She has led clinical trials in the areas of HIV prevention and treatment, serves as the Kansas/Nebraska AIDS Education and Training Center Medical Director for Omaha, and co-directs the preclinical Microbiology and Infectious Diseases curriculum in the medical school.
Christopher Power, MD
Professor, University of Alberta, Edmonton AB Canada
HIV persistence in the CNS: host, viral and environmental determinants
May 17th, 2021 , 12PM ET (11AM CT/9AM PT)
Christopher Power, B.Sc., M.D., F.R.C.P(C) is a Professor at the University of Alberta. He received a B.Sc. from the University of Toronto and an M.D. from the University of Ottawa with subsequent training in medicine and neurology at McMaster University and the University of Western Ontario, respectively, and postdoctoral fellowships at Johns Hopkins University and the National Institutes of Health in neurovirology. Dr. Power is a physician-scientist who studies the mechanisms of neuroinflammatory diseases and their treatments including multiple sclerosis (MS) and neuroHIV. In addition to directing his laboratory, the BrainPowerLab, he is also an attending physician in the University of Alberta HIV and MS Clinics and is the founding Director of the University of Alberta MS Centre. He is an author on over >200 peer-reviewed publications.