2016 Seminars

2016 Pharmacology Seminars

Unless otherwise stated all seminars are held on Friday in Durham Research Center Auditorium (DRC 1002) 9:00-10:00 a.m.

December 16
Fatah Kashanchi, Ph.D.
George Mason University
"Exosomes from HIV, HTLV, Ebola, and Zika infected cells alter recipient cells"

December 2
Iryna Ethell, Ph.D.
University of California, Riverside
"Understanding the Mechanisms of Fragile X Syndrome: from Matrix Metalloproteinase 9 to Perineuronal Nets and Sensory Hypersensitivity"

November 11
St Patrick Reid, Ph.D.
UNMC/Department of Pathology and Microbiology
"Elucidating the critical cellular interactions of emerging viral pathogens"

November 4
Shao-Jun Tang, Ph.D.
University of Texas Medical Branch
"Wnt signaling in HIV-associated pain"

October 28
Nick Dekover (mentor: Steve Bonasera, M.D.)
Pharmacology Graduate Student
"Loss of MHC Class I protein H2-K1 leads to deficits in energy balance, altered mTOR signaling, and obesity"

October 21
James Hilaire (mentor: Howard Gendelman, M.D.)
Pharmacology Graduate Student
"Development and Characterization of Long-Acting Maraviroc Nanoparticles for Antiretroviral Therapy"

Wednesday, October 19; DRCI 1005 from 3-4 p.m.
JoEllyn McMilllan, Ph.D.
UNMC/Department of Pharmacology and Experimental Neuroscience
Promotion and Tenure Seminar
"Nanoformulated Antiretroviral Therapy: From Bench to Bedside"

October 14
Etty (Tika) Benveniste, Ph.D.
University of Alabama at Birmingham
"Protein Kinase CK2 in Cancer and Autoimmunity"

Thursday, October 13; DRCI 1005 from 1-2 p.m.
Benson Edagwa, Ph.D.
UNMC/Department of Pharmacology and Experimental Neuroscience
Promotion and Tenure Seminar
"Medicinal and Polymer Chemistry Strategies to Create Sustained-Release Antiretroviral Products"

Monday, October 11; DRCI 1005 from 1-2 p.m.
Yunlong Huang, Ph.D.
UNMC/Department of Pharmacology and Experimental Neuroscience
Promotion and Tenure Seminar
"Novel Therapeutic Approaches to Central Nervous System Viral Infections"

Monday, October 10; DRCI 1006 from 2-3 p.m.
Tomomi Kiyota, Ph.D.
UNMC/Department of Pharmacology and Experimental Neuroscience
Promotion and Tenure Seminar
"Targeting APP/Aβ trafficking as therapeutic potential of Alzheimer's disease"

October 7
Corey Hopkins, Ph.D.
UNMC/Department of Pharmaceutical Sciences
"Discovery and optimization of novel, small molecules as in vivo tool compounds for CNS disorders"

Wednesday, October 5; DRCI 1005 from 9-10 a.m.
Guoku Hu
UNMC/Department of Pharmacology and Experimental Neuroscience
Promotion and Tenure Seminar
"Exosomal miRNAs Promote Microglial Activation and Contribute to Morphine-associated Neuroinflammation"

September 30; DRCI 1005 from 9-10 a.m.
Minglei Guo, Ph.D.
UNMC/Department of Pharmacology and Experimental Neuroscience
Promotion and Tenure Seminar
"Cocaine-mediated induction of ER stress/autophagy axis: Implications for microglial activation"

September 23; DRCI 1004
Tammy Kielian, Ph.D.
UNMC/Department of Pathology and Microbiology
"Juvenile Batten Disease- New Mechanistic Insights and Potential Therapeutics"

September 9; ESH 3010
Rebecca Oberley Deegan, Ph.D.
UNMC/Biochemistry and Molecular Biology
"Radioprotector for Prostate Cancer"

August 5; 1:40-2:40 p.m.
Han Liu (mentor: Huangui Xiong, Ph.D) Thesis Defense
Pharmacology Graduate Student
"HIV Protein Tat Induces Oligodendrocyte Injury through Increasing Outward K+ Current Carried by KV1.3"

August 5
David E. Warren, Ph.D.
UNMC/Department of Neurological Sciences
"Memory networks of the brain: Investigating the widespread neural substrates of memory with converging methods"

Tuesday, August 2 from 2-3 p.m.
Amit Awasthi, Ph.D.
Translational Health Science and Technology Institute
"Understanding transcriptional regulation of IL-9 in Th9 and Th17 cells in health and diseases"

July 29
Raymond Dingledine, Ph.D.
Emory University School of Medicine
"Roles for Innate Immunity in Epilepsy"

Thursday, July 28
Mahendra Kumar, Ph.D.
University of Miami Health System
"Beautiful South Florida: CVD Risk is high Even Among Young People"

June 24
Megan Bosch (mentor: Tammy Kielian, Ph.D.)
Pharmacology Graduate Student
"Astrocyte Glutamate Regulation and Metabolic Dysfunction Contribute to Neuronal Pathology in Juvenile Neuronal Ceroid Lipofuscinosis"

Thursday, June 23 from 2-3 p.m.
Yui Cai (mentor: Shilpa Buch, Ph.D) Thesis Defense
Pharmacology Graduate Student
"Molecular mechanisms involved in neurotoxicity mediated by HIV proteins and drug abuse"

Wednesday, June 22 from 3-4 p.m.
Beiqing Wu, Mercury (mentor: JIalin Zheng, Ph.D) Thesis Defense
Pharmacology Graduate Student
"The Role of Glutaminase and Extracellular Vesicles in Macrophages and Microglia"

Tuesday, June 7
Andy Zhong, Ph.D.
University of Nebraska at Omaha
"A Fast and Accurate Approach to Predicting Binding Free Energies of Protein/Ligand Complexes"

May 27
Katherine Olson (mentor: Howard E. Gendelman, M.D.)
Pharmacology Graduate Student
"Immunotherapy for Parkinson’s Disease"

May 20
Stephen A. Spector, M.D.
University of California, San Diego
"Autophagy: Killing HIV Where it Hides"

Tuesday, May 17
Brendan Ottemann (mentor: Howard Fox, Ph.D.)
Pharmacology Graduate Student
"The Role of Endocytic Regulatory Proteins in Mitochondrial Function: Relevance for Parkinson's Disease"
Nate Smith (mentor: Howard E. Gendelman, M.D.)
Pharmacology Graduate Student
"Formulation of an IDO Pathway Inhibitor for HIV-1 Treatment"

May 13
Weizhe Li (Mentor: Larisa Poluektova, M.D., Ph.D.)
Pharmacology Graduate Student
"Metabolomics in Translational Chronic Obstructive Pulmonary Disease (COPD) Research"

May 6
Nichole A. Reisdorph, Ph.D., MS
University of Colorado
"Translational Metabolomics in Chronic Obstructive Pulmonary Disease"

Tuesday, April 26
Bradford Berges, Ph.D.
Brigham Young University
"Humanized mice as a model of AIDS pathogenesis"

April 22
Garret Stuber, Ph.D.
University of North Carolina
"Dissecting the Neural Circuits that Mediate Motivated Behaviors"

Wednesday, April 20 - ESH 3010
Emily Harrison (mentor: Howard Fox, Ph.D) Thesis Defense
Pharmacology Graduate Student
"Expression and function of inflammation-associated miRNAs in traumatic brain injury"

April 15
Ryan Y. Wong, Ph.D.
University of Nebraska at Omaha
"Behavioral Neurogenomics of Stress Coping Styles"

April 8
Chris Woldstad (mentor: Mike Boska, Ph.D.)
Pharmacology Graduate Student
"Biodistribution of Folic Acid Coated Magnetite Nanoparticles Using Magnetic Resonance Imaging"
Brady Sillman (mentor: Howard E. Gendelman, M.D.)
Pharmacology Graduate Student
"The one-step, two-step requirements for success in chemical synthesis and formulation of long acting antiretrovirals"

March 25
Han Liu (Mentor: Huangui Xiong, Ph.D.)
Pharmacology Graduate Student
"HIV protein Tat induces oligodendrocyte apoptosis by increasing K+ current carried by KV1.3"

March 18
Xiangyi Wen (mentor: Wallace Thoreson, Ph.D.)
Pharmacology Graduate Student
"Measurements of the Fusion Pore During Synaptic Exocytosis and Endocytosis from Photoreceptors"

February 26
Kiran Sapkota (mentor: Dan Monaghan, Ph.D.)
Pharmacology Graduate Student
"Development and Characterization of Novel NMDA Receptor Modulators"

February 12
Charles Schutt (mentor: R. Lee Mosley, Ph.D.)
Pharmacology Graduate Student
"Effects of granulocyte-macrophage colony stimulating factor on the helper T cells from Parkinson’s disease patients"

February 5
Francois Villinger, D.V.M., Ph.D.
Professor, Emory University & Director, University of Louisiana at Lafayette
"SHIV: How to prevent its transmission but if it does, follow its path"

January 29
Hang Su (mentor: Howard E. Gendelman, M.D.)
Pharmacology Graduate Student
"Evaluation of nanoformulated antiretroviral drug cocktail in acute HIV-1 infected human-PBL reconstituted NSG mice"
Enquan Xu (mentor: Huangui Xiong, M.D., Ph.D.)
Pharmacology Graduate Student
"Inflammasome Activation by Methamphetamine Potentiates LPS Stimulation of IL-1β Production in Microglia"

Monday, January 25
Ted Warren (mentor: Wallace Thoreson, Ph.D) Thesis Defense
Pharmacology Graduate Student
"Mechanisms of inhibitory feedback from horizontal cells to cone photoreceptors"

January 22
Steven U. Walkley, D.V.M., Ph.D.
Albert Einstein College of Medicine
"Lysosomal Diseases: The Second Half Century"