Equipment

Blood Chemistry Analyzer (VS-2)

Model/ company: Vet Scan / (Abaxis)

Short description: Blood cell counts

DLS

Model/ company: NanoZS / (Malvern)

Short description: Dynamic Light Scattering & Zeta Potential meter

Fluorometer

Model/ company: FlouroMax-4 (Horiba)

Short description: Measuring intensity of the fluorescent signal

Field Flow Fractionator (FFF)

Model/ company: Eclipse Dual Tech / (Wyatt)

Short description: Separation and characterization of nanomaterials

Hematology Analyzer (HM-5)

Model/ company: Vet Scan / (Abaxis)

Short description: Blood chemistry analyses

ICP-MS

Model/ company: NexION 300Q / (Perkin Elmer)         

Short description: Inductively Coupled Plasma Mass-Spectrometer

Luminometer

Model/ company: TD-20/20 / (Turner BioSystems)

Short description: sensitive photometer, luminescence

- for measuring live biomass using the ATP assay;

- for use in immunological studies with chemiluminescence technologies;

- for use in various biochemical applications.

Lyophilizer

Model/ company: F-zone 4 / (Labconco)

Short description: Freeze-drying

FreeZone Freeze Dryer is designed to handle the lyophilization needs of research and pilot plant laboratories.

NTA (NanoSight)

Model/ company: NanoSight NS300 (Malvern)

Short description: Nanoparticle Tracking Analyses

The Malvern Panalytical NanoSight NS300 uses the technology of Nanoparticle Tracking Analysis (NTA). This unique technology utilizes the properties of both light scattering and Brownian motion in order to obtain the size distribution and concentration measurement of particles in liquid suspension. A laser beam is passed through the sample chamber, and the particles in suspension in the path of this beam scatter light in such a manner that they can easily be visualized via 20x magnification microscope onto which is mounted a camera. The camera operates at 30 frames per second (fps), capturing a video file of the particles moving under Brownian motion. The software tracks many particles individually and using the Stokes-Einstein equation calculates their hydrodynamic diameters.

The Malvern Panalytical NanoSight NS300 Instrument provides an easy-to-use, reproducible platform for nanoparticle characterization.The NS300 allows rapid, automated analysis of the size distribution and concentration of all types of nanoparticles from 10nm to 2000nm in diameter, depending on the instrument configuration and sample type. With the ability to be supplied with interchangeable laser modules and the introduction of a motorized 6 place filter wheel means different fluorescent labels can be analyzed. Sample temperature is fully programmable through the Nanoparticle Tracking Analysis (NTA) software.

Plate Reader Multi-Mode

Model/ company: Spectra Max M5 / (Molecular Devices)

Short description: Microplate Reader: absorbance / luminescence / fluorescence

Probe Sonicator

Model/ company: S-4000 / (Misonix)

Short description: Ultrasonic homogenizer

Probe Sonicators (Ultrasonic Homogenizers) offer precision engineering with all the features necessary to create a total system for ultrasonic disruption. They can disintegrate most cells, bacteria, spores or tissue. They can prepare an emulsion down to 1/100 of a micron, homogenize "immiscible" liquids, accelerate enzymatic and chemical reactions, stimulate bacterial activity, disperse solids in liquids and degas liquids.

Surface Plasmon Resonance (SPR)

Model/ company: 404 pi / (BiOptix)

Short description: Kinetic studies

Typhoon

Model/ company: FLA 9500 / (GE Healthcare)

Short description: Biomolecular imaging

Typhoon FLA 9500 is a variable mode laser scanner with modular access to the optical components, providing both versatile and flexible imaging for precise quantitation of proteins, nucleic acids, and other biomolecules.

Ultracentrifuge

Model/ company: Optima le-80k / (Beckman)    

Short description: High speed centrifugal separation

Ultracentrifuge is available with a wide variety of rotors suitable for a great range of experiments. Most rotors are designed to hold tubes that contain the samples.

UPLC-MS System

Model/ company: ACQUITY UPLC H-Class / Waters

Short description: Liquid Chromatography

UV-visible Spectrophotometer

Model/ company: UV-1800 / (Shimadzu)

Short description: Quantitative measurement of light absorbance

Nano Spray Dryer

Model/ company: B-90 HP / (BUCHI)

Short description: Produced small particles (0.2-5 µm) in a safe and controlled manner. Gently processed the smallest sample amounts into submicron particles with minimal product loss. 

Key characteristics: Evaporation capacity: 0.2 L / h H2O (higher for organic solvents); Final particle size:  200 nm - 5 μm; Yield: up to 90%

Enabling:
Innovative:
Economic:

Nose-only exposure/inhalation setup

Model/ company: Promo 2000H/ CH Technology

Short description: Nose-Only Directed-Flow Rodent Inhalation Exposure Unit is a modular system for the nose-only exposure of rodents (mice, hamsters, rats, and guinea pigs). With slight modifications it can also be used for ferrets, rabbits, dogs and monkeys.

The system consists of the exposure tower, aerosol spectrometer (to measure aerosol sizes), liquid aerosol generator, and dry powder disperser. The modular exposure tower has stackable exposure modules plus top and bottom sections or plates for introduction and exhaust of test article. Each module has 12 exposure ports, which can be used for exposing up to 12 animals or take animal breathing zone representative samples.