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May 2022 Post-Doctoral Opportunities at UNMC:
College of Public Health Biostats: Department of Biostatistics and Water, Climate and Health (WCH) Program at University of Nebraska Medical Center (UNMC) is seeking an outstanding candidate for a Postdoctoral Research Associate to focus on statistical methodology research on exposure-response modeling. The candidate is expected to work with Dr. Yeongjin Gwon and WCH program research team to (i) develop innovative statistical methods to better understand the public health challenges related to environmental issues including water and climate, and to create solutions to these challenges and (ii) contribute to the mission of WCH program in UNMC. The candidate will be provided opportunity in engaging in interdisciplinary research at UNMC campus. Salary is commensurate with experience and qualifications.
COP Pharmacy Practice and Science: A postdoctoral position is available in the Murry Clinical Pharmacology laboratory at UNMC. The research program is multidisciplinary with opportunities for the application of clinical pharmacology research across the drug discovery and development process. This position will focus on in vitro and in vivo drug metabolism studies, LCMS method development and optimization, pharmacokinetic analysis and drug formulation.
Int Med Cardiovascular Med: Postdoctoral Engineer with expertise on Image Processing to develop fast and robust cardiovascular image processing (segmentation); summarize findings and publish results in research journals; assume general responsibility for scientific operations of the laboratory; provide supervision and guidance to junior technicians, students, and researchers.
Yiannis Chatzizisis, M.D., Ph.D
Eppley Inst Research: Central focus on prostate cancer, how activation of Raf1 drives motility and resultant bone destructive metastasis, and how these processes are modulated by several novel therapeutics created by the laboratory.
Radiation Oncology: A postdoctoral research associate position is available in the lab of Dr. Chi Zhang in the Department of Radiation Oncology to conduct research in the area of molecular biology, cell biology, protein biochemistry, immunohistochemistry, and animal model studies to support the maintenance of existing research projects in brain tumors and, additionally, will contribute to both the optimization of current assays and the development of new technologies.
Pharmacology/Exp Neuroscience: The Department of Pharmacology at the University of Nebraska Medical Center is seeking a highly motivated and skilled researcher with experience in molecular biology and cellular biology skills. This is a key position within the laboratory and will be responsible for planning and execution of experiments in close collaboration with the Principal Investigator. The qualified candidate will also be involved in the preparation of manuscripts and grant proposals..
Munroe-Meyer Institute Administration: The post-doctoral research associate will work in the laboratory of Dr. Jennifer Blackford (principal investigator/PI) to plan, develop, implement, and conduct research projects at the Munroe-Meyer Institute at the University of Nebraska Medical Center. The Blackford lab’s research is focused on understanding the neural basis of anxiety and the role of anxiety neurocircuitry in psychiatric and neurodevelopmental disorders. Projects include ongoing NIMH-funded research in childhood anxiety disorders, NIAAA-funded research in anxiety neurocircuitry in adults with alcohol use disorders, and new studies of anxiety in autism spectrum disorders. Post-doctoral research associates will have opportunities to advance high-impact research projects in these areas, gain expertise in fellowship/grant/manuscript writing, and hone their critical thinking and presentation skills to prepare for careers in academia.
Genetics Cell Biology & Anatomy: The Department of Genetics, Cell Biology and Anatomy is seeking a Bioinformatics Postdoctoral Research Associate. Experience in analysis of high-throughput sequencing (e.g. RNA-seq, ChIP-seq, or ATAC-seq) is needed. Potential projects will investigate mechanistic principles of 3D genome organization and include the relationship between chromatin modifications, transcription factors, transcription, and various features of chromatin folding. Training on the analysis of sequencing-based approaches to study long-range chromatin interactions, Hi-C and HiChIP, will be provided.
Pharmacology/Exp Neuroscience: Seeking a candidate with a PhD degree in biological sciences with expertise in autophagy, inflammasomes, and neuroinflammation in the context of HIV and drugs of abuse comorbidity. Preference will be given to candidates with past experience in neuroinflammation. Specifically, the candidate will have experience in isolation of primary glial cells, and expertise in investigating the role of autophagy, inflammasomes, long non-coding RNAs, and microRNAs in rodents and macaques samples. Additionally, the candidate will have technical skills to apply various state of the art biochemical tools to understand these complex molecular functions in the brain. Desirably, the candidate should have sound knowledge in molecular neurobiology and bioinformatics with ability to deal the next-generation sequencing data. Work will include both in vitro and in vivo models involving cell culture and rodent models of HAND respectively. Candidate should be able to work in a team, develop research ideas and mentor technicians and students in the lab.
Genetics Cell Biology & Anatomy: The Department of Genetics, Cell Biology and Anatomy is recruiting a postdoctoral trainee to pursue exciting research areas in normal/malignant hematopoiesis, and fundamental problems in cellular regulation, including epigenetics. The laboratory is located in the Fred and Pamela Buffett Cancer Center at the University of Nebraska Medical Center, which provides a highly collaborative scholarly environment for conducting innovative basic and translational/clinical research.
Anesthesiology: A Postdoctoral Research Associate position is available immediately in the Department of Anesthesiology at the University of Nebraska Medical Center in Omaha, Nebraska to work on multiple NIH grants to include the study of addiction and sex differences associated with drug relapse. The emphasis is on delineating the role of brain derived extracellular vesicles (BDEs) using preclinical addiction models and further characterizing their role in brain dysfunction. In addition, the successful candidate will also study these BDEs in regulating key mechanisms at the synapse using in vitro approaches. Several high throughput “omics” approaches will also be applied. The successful candidate will work in a small, but growing, lab of an early-career Principal Investigator and will receive significant mentoring in manuscript/grant writing including training junior trainees.
Anesthesiology: A NIH-funded Postdoctoral Research Associate position will be available on December 1st 2019, in the Department of Anesthesiology at the University of Nebraska Medical Center in Omaha, Nebraska. The successful applicant will participate in research focused upon sensory control of cardiovascular and autonomic regulation. Since the primary goal of this newly funded project is to study the interaction between the immune system and the autonomic nerve system in cardiovascular diseases, the applicant is expected to already possess a relatively strong background in immunology and molecular biology. Current projects in the lab include the function and electrophysiology of autonomic neurons and the role of cardiopulmonary and skeletal muscle sensory endings in the pathogenesis of heart failure and hypertension. The applicant will be trained to use cellular, molecular, in vivo and in vitro electrophysiological and integrative approaches to address questions related to this area of research.
Munroe-Meyer Institute: The Blackford Lab is excited to announce a post-doctoral research associate position. We are seeking a collaborative and highly motivated recent PhD graduate with research experience in developmental and/or affective neuroscience or psychology. Post-doctoral research associates in the lab work closely with Dr. Blackford and receive strong mentorship.
Postdoctoral Engineer with expertise on Image Processing to develop fast and robust cardiovascular image processing (segmentation); summarize findings and publish results in research journals; assume general responsibility for scientific operations of the laboratory; provide supervision and guidance to junior technicians, students, and researchers.
Duties:
The Image Processing Engineer will develop and test image processing and data classification algorithms for cardiovascular imaging (IVUS, CT, OCT, MRI…). The Image Processing Engineer will analyze data, develop methods using machine learning for feature extraction and classification, and then finish the image segmentation. A critical aspect of this work is visualizing and communicating results. The Image Processing Engineer will create visual interpretations of data and methods, write reports, and create presentations. The Image Processing Engineer will work as part of a multidisciplinary team, including medicine, simulations, and 3d modeling.
Yiannis Chatzizisis, MD, PhD
The Department of Surgery at the University of Nebraska Medical Center has an opening for a Postdoctoral Research Associate position in a federally-funded laboratory. Applicants must have an MD, PhD, or equivalent. The research will utilize large animal (porcine) models of cancer, limb ischemia, hemorrhage, and other diseases, and will require expertise in cancer biology and methods of molecular biology, gene transfer, gene editing, biochemistry, cell biology, cell culture, and vertebrate animal models, including genetically-engineered mice. No prior experience with swine handling is required. The work will include derivation, characterization, and validation of novel cancer cell lines and viral vectors for in vivo studies, and generation, characterization, and validation of stem cell lines. The projects will be directed by Dr. Mark Carlson. An emphasis will be placed on laboratory technical expertise, scientific experimental design, problem-solving abilities, collaborative skills, communication skills (written and oral), and grantsmanship. Salary and benefits will be commensurate with experience.
Pathology/Microbiology, Cancer Research
Dr. Leah Cook in the Department of Pathology & Microbiology is seeking a Postdoctoral Research Associate to conduct and coordinate research activities in a high paces laboratory that is studying mechanisms of neutrophils in progression and chemo-resistance of pancreatic and prostate caner and exploration of novel therapeutic targets and strategies. The successful candidate will develop and implement tests, methods and procedures; perform research using mouse models, cell culture, and cloning techniques; analyze and review findings; and provide recommendations relevant to the continuation and successful completion of the project(s) and the laboratory. Provides research oversight towards graduate student projects in conjunction with PI. Candidates should hold a Ph.D. degree in cancer, biology, molecular biology, or related scientific field that has been awarded within 3 years of this application, and experience in research laboratory setting, including animal models. Preferred experience in cancer research and redox metabolism research with a knowledge of the development of novel therapeutics, molecular biology techniques and overall understanding of tumor biology.
The Division of Nephrology, University of Nebraska Medical Center (Omaha), seeks a postdoctoral research associate, with a degree in biochemistry, immunology, pharmacology, physiology, pathology, or related field and expertise in immunological responses in vertebrate animals. Required experience includes animal experiments and cell culture work and common cellular immunology and molecular biology techniques. Successful applicant’s work will include investigation of mechanisms of kidney injury in kidney transplantation models. Studies will include investigation of signaling pathways leading to nephrotoxic injury of common immuno-suppressants, and studying the immunological and non-immunological mechanisms of late graft failure. Work will include collection, analysis, and interpretation of data, presentation at professional meetings, manuscript preparation, and grant writing. The successful candidate will have first-author publications in peer-reviewed journals and the ability to write research papers, with goal of multiple grant submissions in the first year. The successful candidate must possess strong verbal and written communication skills and the ability to work independently and as part of a team. Working knowledge of Word, Excel, PowerPoint, and image and statistical analysis software is required.
The Department of Neurological Sciences at the University of Nebraska Medical Center (UNMC) seeks a post-doctoral research associate that will work in thelaboratory of Dr. David E. Warren (principal investigator/PI) with the PI and his research team to plan, develop, implement, and conduct research projects at UNMC. This includes ongoing NIH-funded research in developmental, aging, and neurological populations including healthy children, healthy older adults, and patients on the Alzheimer’s disease continuum. The PI’s lab uses cognitive neuroscience techniques including cognitive assessment, neuropsychology, psychophysical testing, eye-movement monitoring, structural and functional magnetic resonanceimaging, transcranial magnetic stimulation, and genomic assays. Duties involve research study design, participant recruitment, data collection, data analyses, and preparation of scholarly products. Scholarly products will include peer-reviewed publications, conference abstracts, extramural grant applications, progress reports, intramural institutional review board protocols, and other compliance reports as directed. Finally, the post-doc will also work as directed with collaborators at UNMC and other institutions. Postdoctoral research associate will be expected to have strong scientific writing skills and excellent communication skills, good early track record of submitted or published peer-reviewed articles, exceptional organizational skills, ability to work as a team member, ability to advise and supervise more junior laboratory personnel, familiarity with standard office productivity software (e.g., MS Office), and ability to operate standard office equipment (copy machine, fax machine, multi-line phone).
Improving the survival of PDAC patients requires a detailed understanding of underlying molecular signatures that impact disease progression and treatment response. Recent work published by our group identifies 4 distinct subtypes of PDAC through proteomic analysis of clinical samples with longitudinal clinical metadata. We are looking for a talented and motivated Post Doc to identify and validate molecular drivers of pancreatic cancer subtype differentiation using multiomics and molecular biology techniques.
Biochemistry and Molecular Biology
A postdoctoral position is currently available in the Biochemistry and Molecular Biology Department at the University of Nebraska Medical Center focused on identifying mechanisms responsible for Cx43 and Cx45 dysregulation in heart disease. The potential candidate is expected to perform various cell and molecular biology techniques and determine the therapeutic effects of inhibitors on cardiac function in animal models of myocardial infarction.
Ophthalmology and Visual Sciences
A Postdoctoral Research Associate is available in the lab of Professor Iqbal Ahmad (Retinal Stem Cell Biology and Regeneration Lab) in the department of Ophthalmology and Visual Sciences, University of Nebraska Medical Center, for training in neural stem cell biology and neurodegenerative disease modeling. Applicants are required to have a Ph.D. and should have a strong background in cell and molecular biology and hands on experience in related techniques, including primary cell culture. Experience with pluripotent cells (ES and/or iPS cells) is desirable. New graduates or those having completed all formalities of graduation should apply.
The Department of Surgery at the University of Nebraska Medical Center has an opening for a Postdoctoral Research Associate position in a federally-funded laboratory. Applicants must have an MD, PhD, or equivalent. The research will utilize large animal (porcine) models of cancer, limb ischemia, hemorrhage, and other diseases, and will require expertise in cancer biology and methods of molecular biology, gene transfer, gene editing, biochemistry, cell biology, cell culture, and vertebrate animal models, including genetically-engineered mice. No prior experience with swine handling is required. The work will include derivation, characterization, and validation of novel cancer cell lines and viral vectors for in vivo studies, and generation, characterization, and validation of stem cell lines. The projects will be directed by Dr. Mark Carlson. An emphasis will be placed on laboratory technical expertise, scientific experimental design, problem-solving abilities, collaborative skills, communication skills (written and oral), and grantsmanship. Salary and benefits will be commensurate with experience.
Dr. Leah Cook in the Department of Pathology & Microbiology is seeking a Postdoctoral Research Associate to conduct and coordinate research activities in a high paces laboratory that is studying mechanisms of neutrophils in progression and chemo-resistance of pancreatic and prostate caner and exploration of novel therapeutic targets and strategies. The successful candidate will develop and implement tests, methods and procedures; perform research using mouse models, cell culture, and cloning techniques; analyze and review findings; and provide recommendations relevant to the continuation and successful completion of the project(s) and the laboratory. Provides research oversight towards graduate student projects in conjunction with PI. Candidates should hold a Ph.D. degree in cancer, biology, molecular biology, or related scientific field that has been awarded within 3 years of this application, and experience in research laboratory setting, including animal models. Preferred experience in cancer research and redox metabolism research with a knowledge of the development of novel therapeutics, molecular biology techniques and overall understanding of tumor biology.
The Division of Nephrology, University of Nebraska Medical Center (Omaha), seeks a postdoctoral research associate, with a degree in biochemistry, immunology, pharmacology, physiology, pathology, or related field and expertise in immunological responses in vertebrate animals. Required experience includes animal experiments and cell culture work and common cellular immunology and molecular biology techniques. Successful applicant’s work will include investigation of mechanisms of kidney injury in kidney transplantation models. Studies will include investigation of signaling pathways leading to nephrotoxic injury of common immuno-suppressants, and studying the immunological and non-immunological mechanisms of late graft failure. Work will include collection, analysis, and interpretation of data, presentation at professional meetings, manuscript preparation, and grant writing. The successful candidate will have first-author publications in peer-reviewed journals and the ability to write research papers, with goal of multiple grant submissions in the first year. The successful candidate must possess strong verbal and written communication skills and the ability to work independently and as part of a team. Working knowledge of Word, Excel, PowerPoint, and image and statistical analysis software is required.
A NIH-funded postdoctoral position is available in the laboratory of Dr. Tammy Kielian in the Department of Pathology and Microbiology, University of Nebraska Medical Center (UNMC) in Omaha, Nebraska. The candidate will direct independent projects related to the role of innate immunity in host defense against Staphylococcus aureus biofilms using mouse infection models as well as translational research with clinical specimens from patients with biofilm infections. Our laboratory utilizes numerous tools to explore host immune-biofilm crosstalk, including single cell RNA-seq, epigenetic platforms, and transposon sequencing. Requires a PhD in immunology or a related immunology-intensive background and preferred immunology research experience.
The Schott Lab at the University of Nebraska Medical Center is seeking a Postdoctoral Research Associate to study the impact of obesity and alcoholism on the progression of liver disease. Our goal is to explore new molecular mechanisms governing autophagy and lipolysis of lipid droplets during hepatic steatosis, liver injury, and cancer. We are seeking enthusiastic candidates with research interests in one or more of the following areas: cell biology, high resolution light and electron microscopy, live-cell imaging, bioimage analysis, lipid biochemistry, liver disease, cancer, and/or animal models of metabolic disease. High importance will be placed on aiding the successful candidate toward achieving future career goals.
Postdoctoral position to investigate the mechanisms of DNA replication and mutagenesis, with a particular focus on the origin of mutations that cause human diseases. A variety of experimental systems, including yeast Saccharomyces cerevisiae, cultured human cells, in vitro biochemistry, mouse models, and human tissues to understand the link between DNA structure, the function of DNA polymerases and genomic instability.
Biochemistry and Molecular Biology
A postdoctoral position in the Biochemistry and Molecular Biology Department at UNMC is currently available. This position will involve mouse models of leukemia and hematopoiesis. The potential candidate is expected to perform various molecular biology, cell and tissue culture techniques, proteomic analysis, and work with patient samples and mouse models. He/She will also test novel combination therapies to leukemia using mouse models. Additionally, he/she will be responsible for maintaining genetically engineered mouse models of leukemia.
Genetics Cell Biology & Anatomy
Support research projects in Dr. Babu Guda’s laboratory. Specific responsibilities include developing novel computational tools and data analysis pipelines to analyze, integrate, and correlate multi-omics data generated from genomic, metagenomic, epigenomic, transcriptomic, proteomic and metabolomic experiments, write manuscripts and assist in developing grant proposals in novel research areas. Provide training and advice to graduate students in the Guda lab, and participate and present in regional, national and international research conferences. Occasional teaching of lectures in bioinformatics courses.
The individual will perform surgical procedures on experimental rat and swine subjects according to protocols. The individual will also assist in enrolling subjects in ongoing human clinical studies investigating peripheral arterial disease. The individual will maintain documentation related to the enrollment of these subjects and ensure IRB protocols are maintained. He or she will assist in the performance of the muscle biopsy procedures and perform blood draws from patients enrolled in the study. This individual will disburse and track stipend payment to the patients. The individual will help with data management, interpretation of data and preparation of manuscripts and grant reports for both the human and animal studies.
Biochemistry and Molecular Biology
A postdoctoral position currently available in the Biochemistry and Molecular Biology Department at the University of Nebraska Medical Center focused on molecular mechanism for the progression and metastasis of pancreatic cancer. The potential candidate is expected to perform various cell and molecular biology techniques and work with in vitro 3D co-culture and the genetically modified mouse models to evaluate the progression of PDAC. He/she will investigate the role of cancer stem cells contribution to the growth, metastasis and therapy resistance, and how targeting these molecule could enhance the therpeutic efficacy using murine, 3D culture and cell line models.
Cellular/Integrative Physiology
A NIH-funded Postdoctoral Research Associate position is available in the Department of Cellular and Integrative Physiology at the University of Nebraska Medical Center. The candidate will work closely with Dr. Pooneh Bagher and will work with inducible conditional knock out mice, will develop mouse models of diabetes, will perform intraperitoneal injections of therapeutic agents, and will conduct other routine mouse colony maintenance and genotyping tasks. Using a range of diabetic and non-diabetic mice, the successful candidate will perform vascular function assays in vitro (pressure myography, wire myography) and in vivo (laser speckle contrast analysis). The successful candidate will also perform calcium imaging assays on isolated blood vessels. Candidates may be asked to perform Western blotting, PCR analyses and other molecular techniques. Routine responsibilities will include preparing solutions and pharmacological agents, assisting during animal experiments and lab maintenance. They will also contribute to analyzing and interpreting data and will contribute to the presentation of these data in peer-reviewed publications. The successful candidate will contribute to writing manuscripts, will be mentored and will be encouraged to apply for external funding and contribute to the generation of grant applications.
expression, purification and crystallization: biophysical characterization and structural biology experiments.
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