Department of Epidemiology
University of Nebraska Medical Center
College of Public Health
- 2016-present, Assistant Professor, Department of Epidemiology, College of Public Health, University of Nebraska Medical Center, Omaha, NE
- 2015, Associate Professor, Department of Life and Health Sciences, University of Nicosia, Cyprus
- 2010-2015, Director, Mediterranean Center for Cancer Research
- 2008-2015, Assistant Professor, Department of Life and Health Sciences, University of Nicosia, Cyprus
- 2007-2008, Adjunct Faculty, Department of Life and Health Sciences, University of Nicosia, Cyprus
- 2005-2006, Postdoctoral Research Associate, Department of Biological Engineering, MIT, Cambridge, MA
- 2005, PhD, Genetics, Harvard University
- 1999, BSc, Biology, MIT
Dr. Farazi’s research focuses on understanding the complex interactions of genetic and environmental factors in cancer development as well as identification of biomarkers for the early detection of cancer. Her work involves multi-disciplinary research to study the genetic and environmental contributions to cancer by utilizing genetic and systems epidemiology as well as mouse modeling approaches. Her current research includes studying the connection between diabetes, obesity and cancer (with special emphasis on liver and pancreatic cancer) in mouse models and identification of biomarkers for early detection of these cancers. Furthermore, she is applying systems epidemiology approaches to understand how interacting genetic and environmental risk factors (with a strong focus on pollution and nutrition) contribute to breast and pancreatic cancer development. Ultimately, these approaches will be used to study gene-environment interactions in other cancer types such as liver, lung and colorectal cancer. Understanding the interactions between genetic and environmental risk factors is essential for cancer prevention and control.
- P.A. Farazi, J. Glickman, S. Jiang, A. Yu, K.L. Rudolph, and R.A. DePinho, "Differential Impact of Telomere Dysfunction on Initiation and Progression of Hepatocellular Carcinoma", Cancer Research, Vol. 63, pp. 5021-5027, August 15, 2003.
- P.A. Farazi, J. Glickman, J. Horner, and R.A. DePinho, “Cooperative Interactions of p53 Mutation, Telomere Dysfunction, and Chronic Liver Damage in Hepatocellular Carcinoma Progression”, Cancer Research, Vol. 66, pp. 4766-4773, May 1, 2006.
- P.A. Farazi, M. Zeisberg, J. Glickman, Y. Zhang, Raghu Kalluri, and R.A. DePinho, “Chronic Bile Duct Injury Associated with Fibrotic Matrix Microenvironment Provokes Cholangiocarcinoma in p53 Deficient Mice”, Cancer Research, Vol. 66, pp. 6622-6627, July 1, 2006.
- P.A. Farazi, and R.A. DePinho. “Hepatocellular carcinoma pathogenesis: from genes to environment”, Nature Reviews Cancer, Vol. 6, pp. 674-687, September, 2006.
- P.A. Farazi, and R.A DePinho. “The Genetic and Environmental Basis of Hepatocellular Carcinoma”, Discovery Medicine, Vol. 6 (No 35), pp182-186, October, 2006.
- B. Cosgrove, B. M. King, M. Hasan, L. Alexopoulos, P.A. Farazi, B. S. Hendriks, L. G. Griffith, P. K. Sorger, B. Tidor, J. Xu, and D.A. Lauffenburger. “Synergistic Drug-Cytokine Induction of Hepatocellular Death as an in vitro Approach for the Study of Inflammation-Associated Idiosyncratic Hepatotoxicity”, Toxicology and Applied Pharmacology, Vol. 237 (3): pp. 317-330, 15 June 2009.
- P.A. Farazi. “Cancer Trends and Risk Factors in Cyprus”, ecancermedical science, 8: 389, 24 Jan 2014.
- Cooter M, Soliman A, Pavlou P, Demetriou A, Orphanides C, Kritioti E, Banerjee M, and Farazi P.*. “Incidence and Time Trends of Cancer in Cyprus Over 11 Years (1998 – 2008)”, Tumori, 101(1):8-15, Jan-Feb 2015.
- Farazi P.*, Lander L, Pavlou P, Watson K, Le L., and Soliman A. “Geographic trends of tobacco-related cancers in Cyprus”, Tobacco Induced Diseases, 13:21, July 31 2015.
- Farazi P.*, Hadji P, Roupa Z. Awareness of HPV and cervical cancer prevention among Greek healthcare workers, European Journal of Cancer Prevention, in press (2016).
* corresponding author
- International Liver Cancer Association
- International Lung Cancer Consortium
- Society for Applied Biotechnology