Core Facilities
Jump to a Core Facility based on the categories listed below or use Control F to search by keyword
ANIMAL MODELS, BEHAVIOR AND PHYSIOLOGY |
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Resource | Services |
Mouse Behavior Facility | Metabolic Monitoring |
Biological Irradiation Core | Irradiation of small animals, tissue samples, and cultured cells |
Comparative Medicine |
Provides professional veterinary medical, husbandry and proposal review services to support animals used in research |
Echocardiography | Echocardiography |
Electron Paramagnetic Resonance (EPR Spectroscopy) | Free Radical Measurement |
Experimental Irradiation Facility | Gamma Irradiation Source |
Hemodynamics | Hemodynamics |
Mouse Genome Engineering Core | DNA Construct, Genotyping, Knockout Animals, Mouse Strain Rederivation, Transgenic Animals, Speed Congenics |
Translational Mouse Model Core Facility | Provides humanized mouse models |
BIOIMAGING |
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Resource | Services |
Antibody Labeling Facility (ALF) | Radiolabeling |
Bioimaging Facility | Non-human magnetic imaging and tomography (MRI, CT, SPECT) |
UNMC Advanced Microscope Core Facility | Confocal Laser Scanning Microscopy, Super Resolution Fluorescent Microscopy, Live Cell Imaging |
PTI-Delta Scan Fluorimeter | Real time detection and monitoring of intracellular calcium ion concentrations in living cells. |
Electron Microscopy Facility | Transmission and Scanning Electron Microscopy |
IVIS Spectrum in vivo Imaging Core Facility | IVIS optical imaging |
Nanoimaging Core Facility | Combined AFM/Raman supports nanomanipulations and characterization of mechanical, electrical, magnetic properties of samples. |
Nanomaterials Characterization Core Facility | Live animal molecular imaging using high-resolution anatomical X-rays. The facility offers: Inductively Coupled Plasma Mass Spectrometer, Surface Plasmon Resonance, Dynamic Light Scattering, Nanoparticle Tracking Analysis, Multimodal Laser Scanner, and Rodent Hematology & Blood Chemistry Analyzers |
Tissue Sciences Facility | Human and Animal Tissue Pathology, digital Imaging, Slide Scanning, Automated Immunohistochemistry and Specialized Histology |
Ultrasonic Imaging | VEVO Ultrasonic Imaging |
Radiology | Molecular Imaging (PET) Human |
MEG Center | Magnetoencephalography (MEG) Human |
Department of Internal Medicine, Cardiology | Cardiovascular Ultrasound |
CELL AND TISSUE ANALYSIS |
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Resource | Services |
Biological Irradiation Core | Irradiation of small animals, tissue samples, and cultured cells |
Electron Paramagnetic Resonance (EPR Spectroscopy) | Free Radical Measurement |
Tissue Sciences Facility | Human and Animal Tissue Pathology, Digital Imaging, Slide Scanning, Image Analysis, Automated Immunohistochemistry and Specialized Histology |
Elutriation Core Facility | Isolation of monocytes and lymphocytes from peripheral blood mononuclear cells (PBMCs) |
Flow Cytometry Research Facility | Flow Cytometry Services, Cell Separation |
Electron Microscopy Research Facility | Electron Microscopy/Confocal Microscopy |
UNMC Advanced Microscope Core Facility | Confocal Laser Scanning Microscopy, Super Resolution Fluorescent Microscopy, Live Cell Imaging |
Eppley Cancer Center Molecular Biology and HTS Facility | High-throughput chemical, small molecule, and SiRNA (small interfering RNA) screening, High-content cell imaging and analysis, Luminex xMAP technologies |
CLINICAL RESEARCH |
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Resource | Services |
Biologics Production Facility | GMP Facility for the manufacturing, production and modification of cells, tissues, cellular and tissue-derived products |
Biomedical Informatics Facility | Development, maintenance and support of data management systems and disease-specific registries and biobanks; Computational tools for studying structure and function of molecules |
Center for Collaboration on Research Design and Analysis (CCORDA) | Biostatistics, Research Study Design, Surveys and Analysis |
Center for Clinical and Translational Research | Resources for Clinical Research |
Center for Reducing Health Disparities | Consultation on Study Design, Spanish translation services for and promotion and enrollment into research studies |
Clinical Movement Analysis Laboratory | Equipment and resources to support human studies involving physical activity |
Clinical Research Center | Outpatient clinical research facility provides clinical trial support from pre-proposal planning, to clinical services and training. Clinic and laboratory space to conduct clinical trials and nurse coordinators and support staff for clinical trials. |
Epigenomics | DNA Methylation Analysis |
Eppley Cancer Center Protocol Review and Monitoring System | Data & Safety Monitoring |
Electronic Health Record Data Access Core | Electronic health record access; feasibility, cross-sectional, health-outcomes, retrospective data analysis, quality improvement, registry creation, subject recruitment, public health research studies |
Elutriation Core Facility | Isolation of monocytes and lymphocytes from peripheral blood mononuclear cells (PBMCs). |
Eppley Cancer Center Clinical Trials Office | Centralized Protocol and Data Management Unit |
Human Genetics Laboratory | Cytogenetics, FISH studies, Molecular genetics |
Institutional Review Board (IRB) | Assure Protection of all human subjects in research projects on the premises of the UNMC, NMC and UNO |
Investigational Pharmacy | Custom pharmaceutical services for clinical and translational research. Protocol assistance and design, Regulatory Oversight, Inventory Control, Documentation, Dispensing, Drug Information |
MEG Center | Magnetoencephalography (MEG) Human |
Nebraska Biobank | Deidentified serum/plasma or DNA samples available for clinical/translational research projects |
Nebraska Biomechanics Core Facility | Gait analysis, muscular strength testing, endurance analysis, comprehensive balance analysis (on UNO campus) |
Nebraska Nanomedicine Production Plant | Resources to transition nanomedicines from preclinical screening to human clinical trials, including pre-production advisement and product preparation. |
UNMC Genomics Core | Next Generation Sequencing , Whole genome sequencing, High Throughput Traditional Sequencing |
Tissue Banking Core Facility | Tissue for histologic, cytogenetic, immunohistochemical, and molecular analysis |
Tissue Sciences Facility | Human and Animal Tissue Pathology, Digital Imaging, Slide Scanning, Image Analysis, Automated Immunohistochemistry and Specialized Histology |
DATA ANALYSIS AND STATISTICS |
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Resource | Services |
Center for Collaboration on Research Design and Analysis (CCORDA) | Biostatistics, Research Study Design Surveys and Analysis |
GENOMICS |
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Resource | Services |
Flow Cytometry Research Facility | Flow Cytometry Services, Cell Separation |
Eppley Cancer Center Molecular Biology and HTS Facility | High-throughput chemical, small molecule, and SiRNA (small interfering RNA) screening, High-content cell imaging and analysis, Luminex xMAP technologies |
UNMC Genomics Core | DNA Sequencing/Genotyping, Next Generation Sequencing, Whole genome sequencing |
Mouse Genome Engineering Core | DNA Construct, Genotyping, Knockout Animals, Mouse Strain Rederivation, Transgenic Animals, Speed Congenics |
Human Genetics Laboratory | Cytogenetics, FISH studies, Molecular genetics |
Epigenomics | DNA Methylation Analysis |
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Resource | Services |
Biomedical Informatics & Molecular Modeling Facility | Computational Tools for Studying Structure and Function. Development, maintenance and support of data management systems and disease-specific registries and biobanks. |
Bioinformatics and Systems Biology Facility | Biological Data Analysis, Development of Database/Application/Web Interfaces, Ingenuity Pathway Analysis, Whole Genome Mapping, RNAseq Mapping, Exome Sequencing Mapping, Next Generation Sequencing Analysis |
Biomedical Informatics Education | Clinical Informatics, Information Standards (including medical ontologies & vocabularies) and Biomedical Informatics Education. Jim McClay, MD 402-559-35987 Jim Campbell, MD 402-559-7505 |
Center for Collaboration on Research Design & Analysis (CCORDA) | Research Study Design, Biostatistics, Surveys and Statistical Analysis of Datasets |
Electronic Health Record Data Access Core | Electronic Health Record Research, Feasibility Studies, Cross-Sectional Studies, Health Outcomes, Retrospective Data Analysis, Quality Improvement Projects, Public Health Research, Subject Recruitment Case Findings |
Holland Computing Center |
High Performance Computing |
Nebraska Biobank |
Deidentified Database of serum/plasma or DNA samples tied to electronic health information |
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Resource | Services |
Nanoimaging Core Facility | Combined Atomic Force Microscopy (AFM)/Raman supports nanomanipulations and characterization of mechanical, electrical, magnetic properties of samples. AFM capabilities include: topography imaging in air and liquid; force spectroscopy mode; nanoindentation providing elasticity measurements; nanolithography. |
Nanomaterials Characterization Core Facility | Characterization of supramolecular polymer complexes by AUC. Polymer characterization by both Static (SLS) and Dynamic (DLS) Light Scattering. The facility offers: Inductively Coupled Plasma Mass Spectrometer, Surface Plasmon Resonance, Dynamic Light Scattering, Nanoparticle Tracking Analysis, Multimodal Laser Scanner, and Rodent Hematology & Blood Chemistry Analyzers |
Nebraska Nanomedicine Production Plant | Resources to transition nanomedicines from preclinical screening to human clinical trials, including pre-production advisement and product preparation. |
PROTEOMICS AND SYSTEMS BIOLOGY |
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Resource | Services |
Preparative Ultracentrifuge | Separation of high-purity plasmid DNA, subcellular particles and virus isolation |
Bioinformatics and Systems Biology Core | Discovery, Machine Learning Tools to Solve Biological Problems, Method Development, Data Mining and Knowledge Discovery |
Biomedical Informatics Facility | Development, maintenance and support of data management systems and disease-specific registries and biobanks; Computational tools for studying structure and function of molecules |
Circular Dichroism Spectrometer | Characterizes distinct 3-dimensional regions of proteins as they change shape in response to conditions that cause them to fold or unfold |
Electron Paramagnetic Resonance (EPR Spectroscopy) | Free Radical Measurement |
Mass Spectrometry and Proteomics | Mass Spectrometry including MALDI/TOF/TOF, LC-MS/MS such as LTQ Orbitrap, QTRAP and TripleTOF protein identification and quantification. |
Molecular Interactions Core Facility | BIACORE is an optical biosensor that uses surface plasmon resonance (SPR) for real-time monitoring of macromolecular interactions without the need for labels. Affinity measurements, binding kinetics, active concentrations, binding specificity and epitope mapping. Target-ligand interactions |
Nanomaterials Characterization Core Facility | Characterization of supramolecular polymer complexes by AUC. Polymer characterization by both Static (SLS) and Dynamic (DLS) Light Scattering. The facility offers: Inductively Coupled Plasma Mass Spectrometer, Surface Plasmon Resonance, Dynamic Light Scattering, Nanoparticle Tracking Analysis, Multimodal Laser Scanner, and Rodent Hematology & Blood Chemistry Analyzers |
Nuclear Magnetic Resonance | Small molecule characterization, Structural determination of peptides, Drug discovery and Tissue analysis. |
Protein Structure Facility | Amino Acid Analysis, Protein Sequencing, Peptide Separation |
Eppley Cancer Center Molecular Biology and HTS Facility | High-throughput chemical, small molecule, and SiRNA (small interfering RNA) screening, High-content cell imaging and analysis, Luminex xMAP technologies |
The Eppley Structural Biology Facility | Protein expression and purification for static (SLS) and dynamic light scattering(DLS), small angle X-ray scattering (SAXS), crystallization screening and optimization; and structure determination at the atomic level with X-Ray Cyrstallography. Specialized protein samples can also be made for data collection in the NMR core. |
Translational Mouse Model Core | Provides humanized mouse models |