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2023
Ahmad IM, Dafferner AJ, Salloom RJ, Abdalla MY. Heme Oxygenase-1 Inhibition Modulates Autophagy and Augments Arsenic Trioxide Cytotoxicity in Pancreatic Cancer Cells. Biomedicines. 2023 Sep 20;11(9):2580. doi: 10.3390/biomedicines11092580. PMID: 37761021; PMCID: PMC10526552.
Ahmad R, Kumar B, Thapa I, Lama Tamang R, Yadav SK, Washington MK, Talmon GA, Yu AS, Bastola DK, Dhawan P, Singh AB. Claudin-2 protects from colitis-associated cancer by promoting colitis-associated mucosal healing. J Clin Invest. 2023 Oct 10:e170771. doi: 10.1172/JCI170771. Epub ahead of print. PMID: 37815870.
Aripova N, Duryee MJ, England BR, Hunter CD, Mordeson JE, Ryan EM, Daubach EC, Romberger DJ, Thiele GM, Mikuls TR. Citrullinated and malondialdehyde-acetaldehyde modified fibrinogen activates macrophages and promotes an aggressive synovial fibroblast phenotype in patients with rheumatoid arthritis. Front Immunol. 2023 Aug 16;14:1203548. doi: 10.3389/fimmu.2023.1203548. PMID: 37654483; PMCID: PMC10467288.
Basu I, Li H, Trease AJ, Sorgen PL. Regulation of Cx43 Gap Junction Intercellular Communication by Bruton's Tyrosine Kinase and Interleukin-2-Inducible T-Cell Kinase. Biomolecules. 2023 Apr 8;13(4):660. doi: 10.3390/biom13040660. PMID: 37189407; PMCID: PMC10135648.
Bhat AM, Mohapatra BC, Luan H, Mushtaq I, Chakraborty S, Dutta S, Stock MD, Meza JL, Lele SM, Lin MF, Cook LM, Corey E, Morrissey C, Coulter DW, Rowley J, Datta K, Band V, Band H. Role of GD2 and its biosynthetic enzyme GD3 synthase in prostate cancer tumorigenesis. bioRxiv [Preprint]. 2023 Apr 22:2023.03.18.533299. doi: 10.1101/2023.03.18.533299. PMID: 36993422; PMCID: PMC10055271.
Bhatia R, Siddiqui JA, Ganguly K, Thompson CM, Cannon A, Aithal A, Perumal N, Maurya SK, Li X, Cox JL, Gurumurthy CB, Rachagani S, Jain M, Nasser MW, Batra SK, Kumar S. Muc4 loss mitigates epidermal growth factor receptor activity essential for PDAC tumorigenesis. Oncogene. 2023 Mar;42(10):759-770. doi: 10.1038/s41388-022-02587-1. Epub 2023 Jan 9. PMID: 36624189; PMCID: PMC10198580.
Chakraborty S, Bhat AM, Mushtaq I, Luan H, Kalluchi A, Mirza S, Storck MD, Chaturvedi N, Lopez-Guerrero JA, Llombart-Bosch A, Machado I, Scotlandi K, Meza JL, Ghosal G, Coulter DW, Jordan Rowley M, Band V, Mohapatra BC, Band H. EHD1-dependent traffic of IGF-1 receptor to the cell surface is essential for Ewing sarcoma tumorigenesis and metastasis. Commun Biol. 2023 Jul 20;6(1):758. doi: 10.1038/s42003-023-05125-1. PMID: 37474760; PMCID: PMC10359273.
Chaudhary S, Appadurai MI, Maurya SK, Nallasamy P, Marimuthu S, Shah A, Atri P, Ramakanth CV, Lele SM, Seshacharyulu P, Ponnusamy MP, Nasser MW, Ganti AK, Batra SK, Lakshmanan I. MUC16 promotes triple-negative breast cancer lung metastasis by modulating RNA-binding protein ELAVL1/HUR. Breast Cancer Res. 2023 Mar 14;25(1):25. doi: 10.1186/s13058-023-01630-7. PMID: 36918912; PMCID: PMC10012760.
Chemparathy DT, Sil S, Callen S, Chand HS, Sopori M, Wyatt TA, Acharya A, Byrareddy SN, Fox HS, Buch S. Inflammation-Associated Lung Tissue Remodeling and Fibrosis in Morphine-Dependent SIV-Infected Macaques. Am J Pathol. 2023 Apr;193(4):380-391. doi: 10.1016/j.ajpath.2022.12.016. PMID: 37003622; PMCID: PMC10116601.
Jain M, Venkatraman G, Moniaux N, Kaur S, Kumar S, Chakraborty S, Varshney GC, Batra SK. Monoclonal antibodies recognizing the non-tandem repeat regions of the human mucin MUC4 in pancreatic cancer. PLoS One. 2011;6(8):e23344. doi: 10.1371/journal.pone.0023344. Epub 2011 Aug 23. PMID: 21886786; PMCID: PMC3160300.
Jia H, Ding L, Yu A, Tang W, Tang S, Zhang C, Oupický D. A boronate-based modular assembly nanosystem to block the undesirable crosstalk between hepatic stellate cells and Kupffer cells. Bioact Mater. 2022 Aug 2;25:569-579. doi: 10.1016/j.bioactmat.2022.07.018. PMID: 37056257; PMCID: PMC10087950.
Johnson AN, Dickinson J, Nelson A, Gaurav R, Kudrna K, Evans SE, Janike K, Wyatt TA, Poole JA. Effect of epithelial-specific MyD88 signaling pathway on airway inflammatory response to organic dust exposure. J Immunotoxicol. 2023 Dec;20(1):2148782. doi: 10.1080/1547691X.2022.2148782. PMID: 36538286; PMCID: PMC9912912.
Kabakci R, Clark KL, Plewes MR, Monaco CF, Davis JS. Perfluorooctanoic acid (PFOA) inhibits steroidogenesis and mitochondrial function in bovine granulosa cells in vitro. Environ Pollut. 2023 Oct 11;338:122698. doi: 10.1016/j.envpol.2023.122698. Epub ahead of print. PMID: 37832777.
Khan P, Siddiqui JA, Kshirsagar PG, Venkata RC, Maurya SK, Mirzapoiazova T, Perumal N, Chaudhary S, Kanchan RK, Fatima M, Khan MA, Rehman AU, Lakshmanan I, Mahapatra S, Talmon GA, Kulkarni P, Ganti AK, Jain M, Salgia R, Batra SK, Nasser MW. MicroRNA-1 attenuates the growth and metastasis of small cell lung cancer through CXCR4/FOXM1/RRM2 axis. Mol Cancer. 2023 Jan 4;22(1):1. doi: 10.1186/s12943-022-01695-6. PMID: 36597126; PMCID: PMC9811802.
Kong Y, Shi W, Zheng L, Zhang D, Jiang X, Liu B, Xue W, Kuss M, Li Y, Sorgen PL, Duan B. In situ delivery of a curcumin-loaded dynamic hydrogel for the treatment of chronic peripheral neuropathy. J Control Release. 2023 May;357:319-332. doi: 10.1016/j.jconrel.2023.04.002. Epub 2023 Apr 8. PMID: 37028453; PMCID: PMC10164707.
Kumar V, Sethi B, Staller DW, Xin X, Ma J, Dong Y, Talmon GA, Mahato RI. Anti-miR-96 and Hh pathway inhibitor MDB5 synergistically ameliorate alcohol-associated liver injury in mice. Biomaterials. 2023 Apr;295:122049. doi: 10.1016/j.biomaterials.2023.122049. Epub 2023 Feb 17. PMID: 36827892; PMCID: PMC9998370.
Kumari N, Siddhanta K, Panja S, Joshi V, Jogdeo C, Kapoor E, Khan R, Kollala SS, Kumar B, Sil D, Singh AB, Murry DJ, Oupický D. Oral Delivery of Nucleic Acid Therapies for Local and Systemic Action. Pharm Res. 2023 Jan;40(1):107-122. doi: 10.1007/s11095-022-03415-7. Epub 2022 Oct 21. PMID: 36271204; PMCID: PMC9589866.
Liu B, Zhang D, Tu H, Alimi OA, Kong Y, Satyanarayana R, Kuss M, Li Y, Duan B. Red blood cell membrane-camouflaged poly(lactic-co-glycolic acid) microparticles as a potential controlled release drug delivery system for local stellate ganglion microinjection. Acta Biomater. 2023 Apr 15;161:201-212. doi: 10.1016/j.actbio.2023.02.030. Epub 2023 Feb 27. PMID: 36858164; PMCID: PMC10066835.
Liu Y, Jia Z, Ma L, Wang D. Pyrophosphorylated-Cholesterol-Modified Bone-Targeting Liposome Formulation Procedure. Methods Mol Biol. 2023;2622:207-220. doi: 10.1007/978-1-0716-2954-3_18. PMID: 36781763.
Luan H, Bielecki TA, Mohapatra BC, Islam N, Mushtaq I, Bhat AM, Mirza S, Chakraborty S, Raza M, Storck MD, Toss MS, Meza JL, Thoreson WB, Coulter DW, Rakha EA, Band V, Band H. EHD2 overexpression promotes tumorigenesis and metastasis in triple-negative breast cancer by regulating store-operated calcium entry. Elife. 2023 Jan 10;12:e81288. doi: 10.7554/eLife.81288. PMID: 36625722; PMCID: PMC9988264.
Mahalingam S, Bellamkonda R, Arumugam MK, Perumal SK, Yoon J, Casey C, Kharbanda K, Rasineni K. Glucagon-like peptide 1 receptor agonist, exendin-4, reduces alcohol-associated fatty liver disease. Biochem Pharmacol. 2023 Jul;213:115613. doi: 10.1016/j.bcp.2023.115613. Epub 2023 May 19. PMID: 37209859; PMCID: PMC10351880.
Mahato R, Kumar V, Sethi B, Staller D. Gemcitabine elaidate and ONC201 combination therapy inhibits pancreatic cancer in a KRAS mutated syngeneic mouse model. Res Sq [Preprint]. 2023 Jul 11:rs.3.rs-3108907. doi: 10.21203/rs.3.rs-3108907/v1. PMID: 37503215; PMCID: PMC10371096.
Malik JR, Fletcher CV, Podany AT, Dyavar SR, Scarsi KK, Pais GM, Scheetz MH, Avedissian SN. A novel 4-cell in-vitro blood-brain barrier model and its characterization by confocal microscopy and TEER measurement. J Neurosci Methods. 2023 May 15;392:109867. doi: 10.1016/j.jneumeth.2023.109867. Epub 2023 Apr 26. PMID: 37116621; PMCID: PMC10275325.
Monaco CF, Plewes MR, Przygrodzka E, George JW, Qiu F, Xiao P, Wood JR, Cupp AS, Davis JS. Basic fibroblast growth factor induces proliferation and collagen production by fibroblasts derived from the bovine corpus luteum†. Biol Reprod. 2023 Sep 12;109(3):367-380. doi: 10.1093/biolre/ioad065. PMID: 37283496; PMCID: PMC10502575.
Morsy A, Maddeboina K, Gao J, Wang H, Valdez J, Dow LF, Wang X, Trippier PC. Functionalized Allopurinols Targeting Amyloid-Binding Alcohol Dehydrogenase Rescue Aβ-Induced Mitochondrial Dysfunction. ACS Chem Neurosci. 2022 Jul 20;13(14):2176-2190. doi: 10.1021/acschemneuro.2c00246. Epub 2022 Jul 8. PMID: 35802826.
Nallasamy P, Nimmakayala RK, Karmakar S, Leon F, Seshacharyulu P, Lakshmanan I, Rachagani S, Mallya K, Zhang C, Ly QP, Myers MS, Josh L, Grabow CE, Gautam SK, Kumar S, Lele SM, Jain M, Batra SK, Ponnusamy MP. Pancreatic Tumor Microenvironment Factor Promotes Cancer Stemness via SPP1-CD44 Axis. Gastroenterology. 2021 Dec;161(6):1998-2013.e7. doi: 10.1053/j.gastro.2021.08.023. Epub 2021 Aug 19. PMID: 34418441; PMCID: PMC10069715.
Nimmakayala RK, Leon F, Rachagani S, Rauth S, Nallasamy P, Marimuthu S, Shailendra GK, Chhonker YS, Chugh S, Chirravuri R, Gupta R, Mallya K, Prajapati DR, Lele SM, C Caffrey T, L Grem J, Grandgenett PM, Hollingsworth MA, Murry DJ, Batra SK, Ponnusamy MP. Metabolic programming of distinct cancer stem cells promotes metastasis of pancreatic ductal adenocarcinoma. Oncogene. 2021 Jan;40(1):215-231. doi: 10.1038/s41388-020-01518-2. Epub 2020 Oct 27. PMID: 33110235; PMCID: PMC10041665.
Plewes MR, Przygrodzka E, Monaco CF, Snider AP, Keane JA, Burns PD, Wood JR, Cupp AS, Davis JS. Prostaglandin F2α regulates mitochondrial dynamics and mitophagy in the bovine corpus luteum. Life Sci Alliance. 2023 May 15;6(7):e202301968. doi: 10.26508/lsa.202301968. PMID: 37188480; PMCID: PMC10185813.
Plewes MR, Talbott HA, Saviola AJ, Woods NT, Schott MB, Davis JS. Luteal Lipid Droplets: A Novel Platform for Steroid Synthesis. Endocrinology. 2023 Aug 1;164(9):bqad124. doi: 10.1210/endocr/bqad124. PMID: 37586092; PMCID: PMC10445418.
Rauth S, Ganguly K, Atri P, Parte S, Nimmakayala RK, Varadharaj V, Nallasamy P, Vengoji R, Ogunleye AO, Lakshmanan I, Chirravuri R, Bessho M, Cox JL, Foster JM, Talmon GA, Bessho T, Ganti AK, Batra SK, Ponnusamy MP. Elevated PAF1-RAD52 axis confers chemoresistance to human cancers. Cell Rep. 2023 Feb 28;42(2):112043. doi: 10.1016/j.celrep.2023.112043. Epub 2023 Jan 28. PMID: 36709426; PMCID: PMC10374878.
Rohrer KA, Song H, Akbar A, Chen Y, Pramanik S, Wilder PJ, McIntyre EM, Chaturvedi NK, Bhakat KK, Rizzino A, Coulter DW, Ray S. STAT3 Inhibition Attenuates MYC Expression by Modulating Co-Activator Recruitment and Suppresses Medulloblastoma Tumor Growth by Augmenting Cisplatin Efficacy In Vivo. Cancers (Basel). 2023 Apr 11;15(8):2239. doi: 10.3390/cancers15082239. PMID: 37190167; PMCID: PMC10136921.
Sethi B, Kumar V, Jayasinghe TD, Dong Y, Ronning DR, Zhong HA, Coulter DW, Mahato RI. Targeting BRD4 and PI3K signaling pathways for the treatment of medulloblastoma. J Control Release. 2023 Feb;354:80-90. doi: 10.1016/j.jconrel.2022.12.055. Epub 2023 Jan 5. PMID: 36599397; PMCID: PMC9974792.
Shah A, Chaudhary S, Lakshmanan I, Aithal A, Kisling SG, Sorrell C, Marimuthu S, Gautam SK, Rauth S, Kshirsagar P, Cox JL, Natarajan G, Bhatia R, Mallya K, Rachagani S, Nasser MW, Ganti AK, Salgia R, Kumar S, Jain M, Ponnusamy MP, Batra SK. Chimeric antibody targeting unique epitope on onco-mucin16 reduces tumor burden in pancreatic and lung malignancies. NPJ Precis Oncol. 2023 Aug 11;7(1):74. doi: 10.1038/s41698-023-00423-7. PMID: 37567918; PMCID: PMC10421872.
Shahjin F, Patel M, Machhi J, Cohen JD, Nayan MU, Yeapuri P, Zhang C, Waight E, Hasan M, Abdelmoaty MM, Dash PK, Zhou Y, Andreu I, Gendelman HE, Kevadiya BD. Multipolymer microsphere delivery of SARS-CoV-2 antigens. Acta Biomater. 2023 Mar 1;158:493-509. doi: 10.1016/j.actbio.2022.12.043. Epub 2022 Dec 26. PMID: 36581007; PMCID: PMC9791794.
Shi W, Mirza S, Kuss M, Liu B, Hartin A, Wan S, Kong Y, Mohapatra B, Krishnan M, Band H, Band V, Duan B. Embedded Bioprinting of Breast Tumor Cells and Organoids Using Low-Concentration Collagen-Based Bioinks. Adv Healthc Mater. 2023 Oct;12(26):e2300905. doi: 10.1002/adhm.202300905. Epub 2023 Jul 14. PMID: 37422447.
Singh S, Thangaraj A, Chivero ET, Guo ML, Periyasamy P, Buch S. Role of Dysregulated Autophagy in HIV Tat, Cocaine, and cART Mediated NLRP3 Activation in Microglia. J Neuroimmune Pharmacol. 2023 Sep;18(3):327-347. doi: 10.1007/s11481-023-10063-0. Epub 2023 May 6. PMID: 37148425.
Subramani M, Hook MJV, Qiu F, Ahmad I. Human Retinal Ganglion Cells Respond to Evolutionarily Conserved Chemotropic Cues for Intra Retinal Guidance and Regeneration. Stem Cells. 2023 Aug 17:sxad061. doi: 10.1093/stmcls/sxad061. Epub ahead of print. PMID: 37591511.
Tang S, Kapoor E, Ding L, Yu A, Tang W, Hang Y, Smith LM, Sil D, Oupický D. Effect of tocopherol conjugation on polycation-mediated siRNA delivery to orthotopic pancreatic tumors. Biomater Adv. 2023 Feb;145:213236. doi: 10.1016/j.bioadv.2022.213236. Epub 2022 Dec 6. PMID: 36512927; PMCID: PMC9852068.
Thomes PG, Rensch G, Casey CA, Donohue TM Jr. Ethanol Exposure to Ethanol-Oxidizing HEPG2 Cells Induces Intracellular Protein Aggregation. Cells. 2023 Mar 26;12(7):1013. doi: 10.3390/cells12071013. PMID: 37048086; PMCID: PMC10093015.
Thomes PG, Strupp MS, Donohue TM Jr, Kubik JL, Sweeney S, Mahmud R, Schott MB, Schulze RJ, McNiven MA, Casey CA. Hydroxysteroid 17β-dehydrogenase 11 accumulation on lipid droplets promotes ethanol-induced cellular steatosis. J Biol Chem. 2023 Apr;299(4):103071. doi: 10.1016/j.jbc.2023.103071. Epub 2023 Feb 25. PMID: 36849008; PMCID: PMC10060109.
Vijayakumar S, DiGuiseppi JA, Dabestani J, Ryan WG, Vielman Quevedo R, Li Y, Diers J, Tu S, Fleegel J, Nguyen C, Rhoda LM, Imami AS, Hamoud AA, Lovas S, McCullumsmith R, Zallocchi M, Zuo J. In Silico Transcriptome-based Screens Identify Epidermal Growth Factor Receptor Inhibitors as Therapeutics for Noise-induced Hearing Loss. bioRxiv [Preprint]. 2023 Jun 9:2023.06.07.544128. doi: 10.1101/2023.06.07.544128. PMID: 37333346; PMCID: PMC10274759.
Wang G, Li J, Bojmar L, Chen H, Li Z, Tobias GC, Hu M, Homan EA, Lucotti S, Zhao F, Posada V, Oxley PR, Cioffi M, Kim HS, Wang H, Lauritzen P, Boudreau N, Shi Z, Burd CE, Zippin JH, Lo JC, Pitt GS, Hernandez J, Zambirinis CP, Hollingsworth MA, Grandgenett PM, Jain M, Batra SK, DiMaio DJ, Grem JL, Klute KA, Trippett TM, Egeblad M, Paul D, Bromberg J, Kelsen D, Rajasekhar VK, Healey JH, Matei IR, Jarnagin WR, Schwartz RE, Zhang H, Lyden D. Tumour extracellular vesicles and particles induce liver metabolic dysfunction. Nature. 2023 Jun;618(7964):374-382. doi: 10.1038/s41586-023-06114-4. Epub 2023 May 24. PMID: 37225988; PMCID: PMC10330936.
Yu SY, Luan Y, Tang S, Abazarikia A, Dong R, Caffrey TC, Hollingsworth MA, Oupicky D, Kim SY. Uncovering Tumor-Promoting Roles of Activin A in Pancreatic Ductal Adenocarcinoma. Adv Sci (Weinh). 2023 Jun;10(16):e2207010. doi: 10.1002/advs.202207010. Epub 2023 Apr 21. PMID: 37083240; PMCID: PMC10238186.
Zhang W, Shi W, Wu S, Kuss M, Jiang X, Untrauer JB, Reid SP, Duan B. 3D printed composite scaffolds with dual small molecule delivery for mandibular bone regeneration. Biofabrication. 2020 Jun 12;12(3):035020. doi: 10.1088/1758-5090/ab906e. PMID: 32369796; PMCID: PMC8059098.
Zheng L, Spagnol G, Gandhi DR, Sharma K, Kumar V, Patel KP, Sorgen PL. Inhibition of Pyk2 Improves Cx43 Intercalated Disc Localization, Infarct Size, and Cardiac Function in Rats With Heart Failure. Circ Heart Fail. 2023 Aug;16(8):e010294. doi: 10.1161/CIRCHEARTFAILURE.122.010294. Epub 2023 Jul 19. PMID: 37465947; PMCID: PMC10524803.
Zutshi N, Mohapatra BC, Mondal P, An W, Goetz BT, Wang S, Li S, Storck MD, Mercer DF, Black AR, Thayer SP, Black JD, Lin C, Band V, Band H. Cbl and Cbl-b Ubiquitin Ligases are Essential for Intestinal Epithelial Stem Cell Maintenance. bioRxiv [Preprint]. 2023 May 22:2023.05.17.541154. doi: 10.1101/2023.05.17.541154. PMID: 37292716; PMCID: PMC10245689.
2022
Bhatia R, Siddiqui JA, Ganguly K, Thompson CM, Cannon A, Aithal A, Perumal N, Maurya SK, Li X, Cox JL, Gurumurthy CB, Rachagani S, Jain M, Nasser MW, Batra SK, Kumar S. Muc4 loss mitigates epidermal growth factor receptor activity essential for PDAC tumorigenesis. Oncogene. 2023 Jan 9. doi: 10.1038/s41388-022-02587-1. Epub ahead of print. PMID: 36624189.
Bhatia R, Thompson CM, Clement EJ, Ganguly K, Cox JL, Rauth S, Siddiqui JA, Mashiana SS, Jain M, Wyatt TA, Mashiana HS, Singh S, Woods NT, Kharbanda KK, Batra SK, Kumar S. Malondialdehyde-Acetaldehyde Extracellular Matrix Protein Adducts Attenuate Unfolded Protein Response During Alcohol and Smoking-Induced Pancreatitis. Gastroenterology. 2022 Oct;163(4):1064-1078.e10. doi: 10.1053/j.gastro.2022.06.071. Epub 2022 Jul 3. PMID: 35788346; PMCID: PMC9796922.
Dutta S, Polavaram NS, Islam R, Bhattacharya S, Bodas S, Mayr T, Roy S, Albala SAY, Toma MI, Darehshouri A, Borkowetz A, Conrad S, Fuessel S, Wirth M, Baretton GB, Hofbauer LC, Ghosh P, Pienta KJ, Klinkebiel DL, Batra SK, Muders MH, Datta K. Neuropilin-2 regulates androgen-receptor transcriptional activity in advanced prostate cancer. Oncogene. 2022 Jul;41(30):3747-3760. doi: 10.1038/s41388-022-02382-y. Epub 2022 Jun 27. PMID: 35754042.
Ganguly K, Bhatia R, Rauth S, Kisling A, Atri P, Thompson C, Vengoji R, Ram Krishn S, Shinde D, Thomas V, Kaur S, Mallya K, Cox JL, Kumar S, Batra SK. Mucin 5AC Serves as the Nexus for β-Catenin/c-Myc Interplay to Promote Glutamine Dependency During Pancreatic Cancer Chemoresistance. Gastroenterology. 2022 Jan;162(1):253-268.e13. doi: 10.1053/j.gastro.2021.09.017. Epub 2021 Sep 14. PMID: 34534538; PMCID: PMC8678212.
Gautam SK, Dalal V, Sajja BR, Gupta S, Gulati M, Dwivedi NV, Aithal A, Cox JL, Rachagani S, Liu Y, Chung V, Salgia R, Batra SK, Jain M. Endothelin-axis antagonism enhances tumor perfusion in pancreatic cancer. Cancer Lett. 2022 Sep 28;544:215801. doi: 10.1016/j.canlet.2022.215801. Epub 2022 Jun 19. PMID: 35732216.
Islam R, Mishra J, Polavaram NS, Bhattacharya S, Hong Z, Bodas S, Sharma S, Bouska A, Gilbreath T, Said AM, Smith LM, Teply BA, Muders MH, Batra SK, Datta K, Dutta S. Neuropilin-2 axis in regulating secretory phenotype of neuroendocrine-like prostate cancer cells and its implication in therapy resistance. Cell Rep. 2022 Jul 19;40(3):111097. doi: 10.1016/j.celrep.2022.111097. PMID: 35858551; PMCID: PMC9362995.
Lakshmanan I, Marimuthu S, Chaudhary S, Seshacharyulu P, Rachagani S, Muniyan S, Chirravuri-Venkata R, Atri P, Rauth S, Nimmakayala RK, Siddiqui JA, Gautam SK, Shah A, Natarajan G, Parte S, Bhyravbhatla N, Mallya K, Haridas D, Talmon GA, Smith LM, Kumar S, Ganti AK, Jain M, Ponnusamy MP, Batra SK. Muc16 depletion diminishes KRAS-induced tumorigenesis and metastasis by altering tumor microenvironment factors in pancreatic ductal adenocarcinoma. Oncogene. 2022 Nov;41(48):5147-5159. doi: 10.1038/s41388-022-02493-6. Epub 2022 Oct 21. PMID: 36271032.
Leon F, Seshacharyulu P, Nimmakayala RK, Chugh S, Karmakar S, Nallasamy P, Vengoji R, Rachagani S, Cox JL, Mallya K, Batra SK, Ponnusamy MP. Reduction in O-glycome induces differentially glycosylated CD44 to promote stemness and metastasis in pancreatic cancer. Oncogene. 2022 Jan;41(1):57-71. doi: 10.1038/s41388-021-02047-2. Epub 2021 Oct 21. PMID: 34675409; PMCID: PMC8727507.
Machhi J, Yeapuri P, Markovic M, Patel M, Yan W, Lu Y, Cohen JD, Hasan M, Abdelmoaty MM, Zhou Y, Xiong H, Wang X, Mosley RL, Gendelman HE, Kevadiya BD. Europium-Doped Cerium Oxide Nanoparticles for Microglial Amyloid Beta Clearance and Homeostasis. ACS Chem Neurosci. 2022 Apr 20;13(8):1232-1244. doi: 10.1021/acschemneuro.1c00847. Epub 2022 Mar 21. PMID: 35312284; PMCID: PMC9227977.
Marimuthu S, Lakshmanan I, Muniyan S, Gautam SK, Nimmakayala RK, Rauth S, Atri P, Shah A, Bhyravbhatla N, Mallya K, Grandgenett PM, Hollingsworth MA, Datta K, Jain M, Ponnusamy MP, Batra SK. MUC16 Promotes Liver Metastasis of Pancreatic Ductal Adenocarcinoma by Upregulating NRP2-Associated Cell Adhesion. Mol Cancer Res. 2022 Aug 5;20(8):1208-1221. doi: 10.1158/1541-7786.MCR-21-0888. PMID: 35533267; PMCID: PMC9635595.
Mir S, Golden BDO, Griess BJ, Vengoji R, Tom E, Kosmacek EA, Oberley-Deegan RE, Talmon GA, Band V, Teoh-Fitzgerald ML. Upregulation of Nox4 induces a pro-survival Nrf2 response in cancer-associated fibroblasts that promotes tumorigenesis and metastasis, in part via Birc5 induction. Breast Cancer Res. 2022 Jul 14;24(1):48. doi: 10.1186/s13058-022-01548-6. PMID: 35836253; PMCID: PMC9281082.
Mughees M, Kaushal JB, Sharma G, Wajid S, Batra SK, Siddiqui JA. Chemokines and cytokines: Axis and allies in prostate cancer pathogenesis. Semin Cancer Biol. 2022 Nov;86(Pt 3):497-512. doi: 10.1016/j.semcancer.2022.02.017. Epub 2022 Feb 16. PMID: 35181473; PMCID: PMC9793433.
Nimmakayala RK, Ogunleye AO, Parte S, Krishna Kumar N, Raut P, Varadharaj V, Perumal NK, Nallasamy P, Rauth S, Cox JL, Lele SM, Batra SK, Ponnusamy MP. PAF1 cooperates with YAP1 in metaplastic ducts to promote pancreatic cancer. Cell Death Dis. 2022 Oct 1;13(10):839. doi: 10.1038/s41419-022-05258-x. PMID: 36180487; PMCID: PMC9525575.
Peng ZH, Jogdeo CM, Li J, Xie Y, Wang Y, Sheinin YM, Kopeček J, Oupický D. Tumor Microenvironment-Responsive Polymeric iRGD and Doxorubicin Conjugates Reduce Spontaneous Lung Metastasis in an Orthotopic Breast Cancer Model. Pharmaceutics. 2022 Aug 18;14(8):1725. doi: 10.3390/pharmaceutics14081725. PMID: 36015351; PMCID: PMC9416753.
Phillips AJ, Lobl MB, Hafeji YA, Safranek HR, Mohr AM, Mott JL. Glycosylation of FGFR4 in cholangiocarcinoma regulates receptor processing and cancer signaling. J Cell Biochem. 2022 Mar;123(3):568-580. doi: 10.1002/jcb.30204. Epub 2022 Jan 4. PMID: 34981854; PMCID: PMC8940645.
Pothuraju R, Pai P, Chaudhary S, Siddiqui JA, Cox JL, Kaur S, Rachagani S, Roy HK, Bouvet M, Batra SK. Depletion of transmembrane mucin 4 (Muc4) alters intestinal homeostasis in a genetically engineered mouse model of colorectal cancer. Aging (Albany NY). 2022 Mar 7;14(5):2025-2046. doi: 10.18632/aging.203935. Epub 2022 Mar 7. PMID: 35255004; PMCID: PMC8954958.
Seshacharyulu P, Halder S, Nimmakayala R, Rachagani S, Chaudhary S, Atri P, Chirravuri-Venkata R, Ouellette MM, Carmicheal J, Gautam SK, Vengoji R, Wang S, Li S, Smith L, Talmon GA, Klute K, Ly Q, Reames BN, Grem JL, Berim L, Padussis JC, Kaur S, Kumar S, Ponnusamy MP, Jain M, Lin C, Batra SK. Disruption of FDPS/Rac1 axis radiosensitizes pancreatic ductal adenocarcinoma by attenuating DNA damage response and immunosuppressive signalling. EBioMedicine. 2022 Jan;75:103772. doi: 10.1016/j.ebiom.2021.103772. Epub 2021 Dec 28. PMID: 34971971; PMCID: PMC8718746.
Zeng Y, Yin L, Zhou J, Zeng R, Xiao Y, Black AR, Hu T, Singh PK, Yin F, Batra SK, Yu F, Chen Y, Dong J. MARK2 regulates chemotherapeutic responses through class IIa HDAC-YAP axis in pancreatic cancer. Oncogene. 2022 Jul;41(31):3859-3875. doi: 10.1038/s41388-022-02399-3. Epub 2022 Jul 2. PMID: 35780183; PMCID: PMC9339507.
Zhang C, Atri P, Nallasamy P, Parte S, Rauth S, Nimmakayala RK, Marimuthu S, Chirravuri-Venkata R, Bhatia R, Halder S, Shah A, Cox JL, Smith L, Kumar S, Foster JM, Kukreja RC, Seshacharyulu P, Ponnusamy MP, Batra SK. Small molecule inhibitor against onco-mucins disrupts Src/FosL1 axis to enhance gemcitabine efficacy in pancreatic ductal adenocarcinoma. Cancer Lett. 2022 Sep 19;551:215922. doi: 10.1016/j.canlet.2022.215922. Epub ahead of print. PMID: 36285687.
Ding L, Tang S, Yu A, Wang A, Tang W, Jia H, Oupický D. Nanoemulsion-Assisted siRNA Delivery to Modulate the Nervous Tumor Microenvironment in the Treatment of Pancreatic Cancer. ACS Appl Mater Interfaces. 2022 Mar 2;14(8):10015-10029. doi: 10.1021/acsami.1c21997. Epub 2022 Feb 21. PMID: 35188730; PMCID: PMC9153289.
Frodyma DE, Troia TC, Rao C, Svoboda RA, Berg JA, Shinde DD, Thomas VC, Lewis RE, Fisher KW. PGC-1β and ERRα Promote Glutamine Metabolism and Colorectal Cancer Survival via Transcriptional Upregulation of PCK2. Cancers (Basel). 2022 Oct 5;14(19):4879. doi: 10.3390/cancers14194879. PMID: 36230802; PMCID: PMC9562873.
Khan R, Panja S, Ding L, Tang S, Tang W, Kapoor E, Bennett RG, Oupický D. Polymeric Chloroquine as an Effective Antimigration Agent in the Treatment of Pancreatic Cancer. Mol Pharm. 2022 Dec 5;19(12):4631-4643. doi: 10.1021/acs.molpharmaceut.2c00596. Epub 2022 Nov 8. PMID: 36346968.
Laliwala A, Daverey A, Agrawal SK, Dash AK. Alpha Tocopherol Loaded Polymeric Nanoparticles: Preparation, Characterizations, and In Vitro Assessments Against Oxidative Stress in Spinal Cord Injury Treatment. AAPS PharmSciTech. 2022 Jul 13;23(6):195. doi: 10.1208/s12249-022-02345-2. PMID: 35831684.
Ouellette SP, Fisher-Marvin LA, Harpring M, Lee J, Rucks EA, Cox JV. Localized cardiolipin synthesis is required for the assembly of MreB during the polarized cell division of Chlamydia trachomatis. PLoS Pathog. 2022 Sep 12;18(9):e1010836. doi: 10.1371/journal.ppat.1010836. PMID: 36095021; PMCID: PMC9499288.
Pramanik S, Chen Y, Song H, Khutsishvili I, Marky LA, Ray S, Natarajan A, Singh PK, Bhakat KK. The human AP-endonuclease 1 (APE1) is a DNA G-quadruplex structure binding protein and regulates KRAS expression in pancreatic ductal adenocarcinoma cells. Nucleic Acids Res. 2022 Apr 8;50(6):3394-3412. doi: 10.1093/nar/gkac172. PMID: 35286386; PMCID: PMC8990529.
Rajesh C, Sagar S, Rathinavel AK, Chemparathy DT, Peng XL, Yeh JJ, Hollingsworth MA, Radhakrishnan P. Truncated O-Glycan-Bearing MUC16 Enhances Pancreatic Cancer Cells Aggressiveness via α4β1 Integrin Complexes and FAK Signaling. Int J Mol Sci. 2022 May 13;23(10):5459. doi: 10.3390/ijms23105459. PMID: 35628269; PMCID: PMC9141077.
Tang S, Kapoor E, Ding L, Yu A, Tang W, Hang Y, Smith LM, Sil D, Oupický D. Effect of tocopherol conjugation on polycation-mediated siRNA delivery to orthotopic pancreatic tumors. Biomater Adv. 2022 Dec 6;145:213236. doi: 10.1016/j.bioadv.2022.213236. Epub ahead of print. PMID: 36512927.
Tang W, Panja S, Jogdeo CM, Tang S, Ding L, Yu A, Foster KW, Dsouza DL, Chhonker YS, Jensen-Smith H, Jang HS, Boesen EI, Murry DJ, Padanilam B, Oupický D. Modified chitosan for effective renal delivery of siRNA to treat acute kidney injury. Biomaterials. 2022 Jun;285:121562. doi: 10.1016/j.biomaterials.2022.121562. Epub 2022 May 2. PMID: 35552115; PMCID: PMC9133205.
Tang W, Panja S, Jogdeo CM, Tang S, Yu A, Oupický D. Study of Renal Accumulation of Targeted Polycations in Acute Kidney Injury. Biomacromolecules. 2022 May 9;23(5):2064-2074. doi: 10.1021/acs.biomac.2c00079. Epub 2022 Apr 8. PMID: 35394757; PMCID: PMC9150723.
Wang O, Han L, Lin H, Tian M, Zhang S, Duan B, Chung S, Zhang C, Lian X, Wang Y, Lei Y. Fabricating 3-dimensional human brown adipose microtissues for transplantation studies. Bioact Mater. 2022 Oct 27;22:518-534. doi: 10.1016/j.bioactmat.2022.10.022. PMID: 36330162; PMCID: PMC9619153.
Wu S, Li Y, Zhang C, Tao L, Kuss M, Lim JY, Butcher J, Duan B. Tri-Layered and Gel-Like Nanofibrous Scaffolds with Anisotropic Features for Engineering Heart Valve Leaflets. Adv Healthc Mater. 2022 May;11(10):e2200053. doi: 10.1002/adhm.202200053. Epub 2022 Mar 21. PMID: 35289986.
Wu S, Qi Y, Shi W, Kuss M, Chen S, Duan B. Electrospun conductive nanofiber yarns for accelerating mesenchymal stem cells differentiation and maturation into Schwann cell-like cells under a combination of electrical stimulation and chemical induction. Acta Biomater. 2022 Feb;139:91-104. doi: 10.1016/j.actbio.2020.11.042. Epub 2020 Nov 30. PMID: 33271357; PMCID: PMC8164650.
Xue W, Kong Y, Abu R, Roy P, Huh SH, Kuss M, Kumar V, Duan B. Regulation of Schwann Cell and DRG Neurite Behaviors within Decellularized Peripheral Nerve Matrix. ACS Appl Mater Interfaces. 2022 Feb 23;14(7):8693-8704. doi: 10.1021/acsami.1c20320. Epub 2022 Feb 11. PMID: 35148064.
Yu A, Tang S, Ding L, Foley J, Tang W, Jia H, Panja S, Holbert CE, Hang Y, Stewart TM, Smith LM, Sil D, Casero RA Jr, Oupický D. Hyaluronate-coated perfluoroalkyl polyamine prodrugs as bioactive siRNA delivery systems for the treatment of peritoneal cancers. Biomater Adv. 2022 May;136:212755. doi: 10.1016/j.bioadv.2022.212755. Epub 2022 Mar 17. PMID: 35929290.
Zhang C, Hang Y, Tang W, Sil D, Jensen-Smith HC, Bennett RG, McVicker BL, Oupický D. Dually Active Polycation/miRNA Nanoparticles for the Treatment of Fibrosis in Alcohol-Associated Liver Disease. Pharmaceutics. 2022 Mar 18;14(3):669. doi: 10.3390/pharmaceutics14030669. PMID: 35336043; PMCID: PMC8949580.
Zhang D, Tu H, Hu W, Duan B, Zimmerman MC, Li YL. Hydrogen Peroxide Scavenging Restores N-Type Calcium Channels in Cardiac Vagal Postganglionic Neurons and Mitigates Myocardial Infarction-Evoked Ventricular Arrhythmias in Type 2 Diabetes Mellitus. Front Cardiovasc Med. 2022 Apr 25;9:871852. doi: 10.3389/fcvm.2022.871852. PMID: 35548411; PMCID: PMC9082497.
Xue W, Liu B, Zhang H, Ryu S, Kuss M, Shukla D, Hu G, Shi W, Jiang X, Lei Y, Duan B. Controllable fabrication of alginate/poly-L-ornithine polyelectrolyte complex hydrogel networks as therapeutic drug and cell carriers. Acta Biomater. 2022 Jan 15; 138:182-192. doi: 10.1016/j.actbio.2021.11.004. Epub 2021 Nov 10. PMID: 34774784.
Leon F, Seshacharyulu P, Nimmakayala RK, Chugh S, Karmakar S, Nallasamy P, Vengoji R, Rachagani S, Cox JL, Mallya K, Batra SK, Ponnusamy MP. Reduction in O-glycome induces differentially glycosylated CD44 to promote stemness and metastasis in pancreatic cancer. Oncogene. 2022 Jan;41(1):57-71. doi: 10.1038/s41388-021-02047-2. Epub 2021 Oct 21. PMID: 34675409; PMCID: PMC8727507.
2021
Al-Mugotir M, Lovelace JJ, George J, Bessho M, Pal D, Struble L, Kolar C, Rana S, Natarajan A, Bessho T, Borgstahl GEO. Selective killing of homologous recombination-deficient cancer cell lines by inhibitors of the RPA:RAD52 protein-protein interaction. PLoS One. 2021 Mar 30;16(3): e0248941. doi: 10.1371/journal.pone.0248941. PMID: 33784323; PMCID: PMC8009417.
Bhattacharya DS, Bapat A, Svechkarev D, Mohs AM. Water-Soluble Blue Fluorescent Nonconjugated Polymer Dots from Hyaluronic Acid and Hydrophobic Amino Acids. ACS Omega. 2021 Jul 9;6(28):17890-17901. doi: 10.1021/acsomega.1c01343. Erratum in: ACS Omega. 2021 Oct 05;6(41):27598. PMID: 34308024; PMCID: PMC8296014.
Casey CA, Macke AJ, Gough RR, Pachikov AN, Morris ME, Thomes PG, Kubik JL, Holzapfel MS, Petrosyan A. Alcohol-Induced Liver Injury: Down-regulation and Redistribution of Rab3D Results in Atypical Protein Trafficking. Hepatol Commun. 2021 Sep 7. doi: 10.1002/hep4.1811. Epub ahead of print. PMID: 34494400.
Chaudhary S, Pothuraju R, Rachagani S, Siddiqui JA, Atri P, Mallya K, Nasser MW, Sayed Z, Lyden ER, Smith L, Gupta SD, Ralhan R, Lakshmanan I, Jones DT, Ganti AK, Macha MA, Batra SK. Dual blockade of EGFR and CDK4/6 delays head and neck squamous cell carcinoma progression by inducing metabolic rewiring. Cancer Lett. 2021 Jul 10; 510:79-92. doi: 10.1016/j.canlet.2021.04.004. Epub 2021 Apr 17. PMID: 33878394; PMCID: PMC8153085.
Farmer T, Xie S, Naslavsky N, Stöckli J, James DE, Caplan S. Defining the protein and lipid constituents of tubular recycling endosomes. J Biol Chem. 2021 Jan-Jun;296:100190. doi: 10.1074/jbc.RA120.015992. Epub 2021 Jan 28. PMID: 33334886; PMCID: PMC7948492.
Kaushal JB, Bhatia R, Kanchan RK, Raut P, Mallapragada S, Ly QP, Batra SK, Rachagani S. Repurposing Niclosamide for Targeting Pancreatic Cancer by Inhibiting Hh/Gli Non-Canonical Axis of Gsk3β. Cancers (Basel). 2021 Jun 22;13(13):3105. doi: 10.3390/cancers13133105.
Muthuraj PG, Pattnaik A, Sahoo PK, Islam MT, Pattnaik AK, Byrareddy SN, Hanson C, Anderson Berry A, Kachman SD, Natarajan SK. Palmitoleate Protects against Zika Virus-Induced Placental Trophoblast Apoptosis. Biomedicines. 2021 Jun 4;9(6):643. doi: 10.3390/biomedicines9060643. PMID: 34200091; PMCID: PMC8226770.
Pachikov AN, Gough RR, Christy CE, Morris ME, Casey CA, LaGrange CA, Bhat G, Kubyshkin AV, Fomochkina II, Zyablitskaya EY, Makalish TP, Golubinskaya EP, Davydenko KA, Eremenko SN, Riethoven JM, Maroli AS, Payne TS, Powers R, Lushnikov AY, Macke AJ, Petrosyan A. The non-canonical mechanism of ER stress-mediated progression of prostate cancer. J Exp Clin Cancer Res. 2021 Sep 14;40(1):289. doi: 10.1186/s13046-021-02066-7. PMID: 34521429; PMCID: PMC8439065.
Polavaram NS, Dutta S, Islam R, Bag AK, Roy S, Poitz D, Karnes J, Hofbauer LC, Kohli M, Costello BA, Jimenez R, Batra SK, Teply BA, Muders MH, Datta K. Tumor- and osteoclast-derived NRP2 in prostate cancer bone metastases. Bone Res. 2021 May 14;9(1):24. doi: 10.1038/s41413-021-00136-2. PMID: 33990538; PMCID: PMC8121836.
Przygrodzka E, Hou X, Zhang P, Plewes MR, Franco R, Davis JS. PKA and AMPK Signaling Pathways Differentially Regulate Luteal Steroidogenesis. Endocrinology. 2021 Apr 1;162(4):bqab015. doi: 10.1210/endocr/bqab015. PMID: 33502468; PMCID: PMC7899060.
Qiao F, Law HC, Krieger KL, Clement EJ, Xiao Y, Buckley SM, Woods NT. Ctdp1 deficiency leads to early embryonic lethality in mice and defects in cell cycle progression in MEFs. Biol Open. 2021 Jan 6;10(1): bio057232. doi: 10.1242/bio.057232. PMID: 33408128; PMCID: PMC7803460.
Rao C, Frodyma DE, Southekal S, Svoboda RA, Black AR, Guda C, Mizutani T, Clevers H, Johnson KR, Fisher KW, Lewis RE. KSR1- and ERK-dependent translational regulation of the epithelial-to-mesenchymal transition. Elife. 2021 May 10;10: e66608. doi: 10.7554/eLife.66608. PMID: 33970103; PMCID: PMC8195604.
Sagar, S., Leiphrakpam, P. D., Thomas, D., McAndrews, K. L., Caffrey, T. C., Swanson, B. J., Clausen, H., Wandall, H. H., Hollingsworth, M. A., & Radhakrishnan, P. (2021). MUC4 enhances gemcitabine resistance and malignant behaviour in pancreatic cancer cells expressing cancer-associated short O-glycans. Cancer Letters, 503, 91-102.
Saleem I, Mirza S, Sarkar A, Raza M, Mohapatra B, Mushtaq I, Kim JH, Mishra NK, Alsaleem MA, Rakha EA, Qiu F, Guda C, Band H, Band V. The Mammalian Ecdysoneless Protein Interacts with RNA Helicase DDX39A To Regulate Nuclear mRNA Export. Mol Cell Biol. 2021 Jun 23;41(7):e0010321. doi: 10.1128/MCB.00103-21. Epub 2021 Jun 23. PMID: 33941617; PMCID: PMC8224239.
Sweeter JM, Kudrna K, Hunt K, Thomes P, Dickey BF, Brody SL, Dickinson JD. Autophagy of mucin granules contributes to resolution of airway mucous metaplasia. Sci Rep. 2021 Jun 22;11(1):13037. doi: 10.1038/s41598-021-91932-7. PMID: 34158522; PMCID: PMC8219712.
Thomas D, Sagar S, Liu X, Lee HR, Grunkemeyer JA, Grandgenett PM, Caffrey T, O'Connell KA, Swanson B, Marcos-Silva L, Steentoft C, Wandall HH, Maurer HC, Peng XL, Yeh JJ, Qiu F, Yu F, Madiyalakan R, Olive KP, Mandel U, Clausen H, Hollingsworth MA, Radhakrishnan P. Isoforms of MUC16 activate oncogenic signaling through EGF receptors to enhance the progression of pancreatic cancer. Mol Ther. 2021 Apr 7;29(4):1557-1571. doi: 10.1016/j.ymthe.2020.12.029. Epub 2020 Dec 25. PMID: 33359791; PMCID: PMC8058431.
Vengoji R, Atri P, Macha MA, Seshacharyulu P, Perumal N, Mallya K, Liu Y, Smith LM, Rachagani S, Mahapatra S, Ponnusamy MP, Jain M, Batra SK, Shonka N. Differential gene expression-based connectivity mapping identified novel drug candidate and improved Temozolomide efficacy for Glioblastoma. J Exp Clin Cancer Res. 2021 Oct 25;40(1):335. doi: 10.1186/s13046-021-02135-x. PMID: 34696786; PMCID: PMC8543939.
Wyatt TA, Warren KJ, Wetzel TJ, Suwondo T, Rensch GP, DeVasure JM, Mosley DD, Kharbanda KK, Thiele GM, Burnham EL, Bailey KL, Yeligar SM. Malondialdehyde-Acetaldehyde Adduct Formation Decreases Immunoglobulin A Transport across Airway Epithelium in Smokers Who Abuse Alcohol. Am J Pathol. 2021 Oct;191(10):1732-1742. doi: 10.1016/j.ajpath.2021.06.007. Epub 2021 Jun 27. PMID: 34186073; PMCID: PMC8485061.
2020
Dhawan K, Naslavsky N, Caplan S. Sorting nexin 17 (SNX17) links endosomal sorting to Eps15 homology domain protein 1 (EHD1)-mediated fission machinery. J Biol Chem. 2020 Mar 20;295(12):3837-3850. doi: 10.1074/jbc.RA119.011368. Epub 2020 Feb 10. PMID: 32041776; PMCID: PMC7086038.
Mukadam IZ, Machhi J, Herskovitz J, Hasan M, Oleynikov MD, Blomberg WR, Svechkarev D, Mohs AM, Zhou Y, Dash P, McMillan J, Gorantla S, Garrison J, Gendelman HE, Kevadiya BD. Rilpivirine-associated aggregation-induced emission enables cell-based nanoparticle tracking. Biomaterials. 2020 Feb; 231:119669. doi: 10.1016/j.biomaterials.2019.119669. Epub 2019 Dec 7. PMID: 31865227; PMCID: PMC7334833.
Roychoudhury S, Pramanik S, Harris HL, Tarpley M, Sarkar A, Spagnol G, Sorgen PL, Chowdhury D, Band V, Klinkebiel D, Bhakat KK. Endogenous oxidized DNA bases and APE1 regulate the formation of G-quadruplex structures in the genome. Proc Natl Acad Sci U S A. 2020 May 26;117(21):11409-11420. doi: 10.1073/pnas.1912355117. Epub 2020 May 13. PMID: 32404420; PMCID: PMC7260947.
Wu S, Zhou R, Zhou F, Streubel PN, Chen S, Duan B. Electrospun thymosin Beta-4 loaded PLGA/PLA nanofiber/ microfiber hybrid yarns for tendon tissue engineering application. Mater Sci Eng C Mater Biol Appl. 2020 Jan;106:110268. doi: 10.1016/j.msec.2019.110268. Epub 2019 Oct 12. PMID: 31753373; PMCID: PMC7061461.
Zheng L, Chenavas S, Kieken F, Trease A, Brownell S, Anbanandam A, Sorgen PL, Spagnol G. Calmodulin Directly Interacts with the Cx43 Carboxyl-Terminus and Cytoplasmic Loop Containing Three ODDD-Linked Mutants (M147T, R148Q, and T154A) that Retain α-Helical Structure, but Exhibit Loss-of-Function and Cellular Trafficking Defects. Biomolecules. 2020 Oct 17;10(10):1452. doi: 10.3390/biom10101452. PMID: 33080786; PMCID: PMC7602980.
Zheng L, Trease AJ, Katsurada K, Spagnol G, Li H, Shi W, Duan B, Patel KP, Sorgen PL. Inhibition of Pyk2 and Src activity improves Cx43 gap junction intercellular communication. J Mol Cell Cardiol. 2020 Dec; 149:27-40. doi: 10.1016/j.yjmcc.2020.09.004. Epub 2020 Sep 18. PMID: 32956670; PMCID: PMC7736531.
2019
Farmer T, O'Neill KL, Naslavsky N, Luo X, Caplan S. Retromer facilitates the localization of Bcl-xL to the mitochondrial outer membrane. Mol Biol Cell. 2019 May 1;30(10):1138-1146. doi: 10.1091/mbc. E19-01-0044. Epub 2019 Mar 6. PMID: 30840537; PMCID: PMC6724524.
Frisbie CP, Lushnikov AY, Krasnoslobodtsev AV, Riethoven JM, Clarke JL, Stepchenkova EI, Petrosyan A. Post-ER Stress Biogenesis of Golgi Is Governed by Giantin. Cells. 2019 Dec 13;8(12):1631. doi: 10.3390/cells8121631. PMID: 31847122; PMCID: PMC6953117.
Hein AL, Brandquist ND, Ouellette CY, Seshacharyulu P, Enke CA, Ouellette MM, Batra SK, Yan Y. PR55α regulatory subunit of PP2A inhibits the MOB1/LATS cascade and activates YAP in pancreatic cancer cells. Oncogenesis. 2019 Oct 28;8(11):63. doi: 10.1038/s41389-019-0172-9. PMID: 31659153; PMCID: PMC6817822.
Hu H, Petrosyan A, Osna NA, Liu T, Olou AA, Alakhova DY, Singh PK, Kabanov AV, Faber EA Jr, Bronich TK. Pluronic block copolymers enhance the anti-myeloma activity of proteasome inhibitors. J Control Release. 2019 Jul 28;306:149-164. doi: 10.1016/j.jconrel.2019.05.026. Epub 2019 May 20. PMID: 31121280; PMCID: PMC6822276.
Lee D, Erickson A, Dudley AT, Ryu S. A Microfluidic Platform for Stimulating Chondrocytes with Dynamic Compression. J Vis Exp. 2019 Sep 13;(151):10.3791/59676. doi: 10.3791/59676. PMID: 31566611; PMCID: PMC7222626.
Manca S, Frisbie CP, LaGrange CA, Casey CA, Riethoven JM, Petrosyan A. The Role of Alcohol-Induced Golgi Fragmentation for Androgen Receptor Signaling in Prostate Cancer. Mol Cancer Res. 2019 Jan;17(1):225-237. doi: 10.1158/1541-7786.MCR-18-0577. Epub 2018 Sep 17. PMID: 30224543; PMCID: PMC6318054.
Miller DR, Ingersoll MA, Chatterjee A, Baker B, Shrishrimal S, Kosmacek EA, Zhu Y, Cheng PW, Oberley-Deegan RE, Lin MF. p66Shc protein through a redox mechanism enhances the progression of prostate cancer cells towards castration-resistance. Free Radic Biol Med. 2019 Aug 1; 139:24-34. doi: 10.1016/j.freeradbiomed.2019.05.015. Epub 2019 May 14. PMID: 31100478; PMCID: PMC6620027.
Mishra B, Lakshmaiah Narayana J, Lushnikova T, Wang X, Wang G. Low cationicity is important for systemic in vivo efficacy of database-derived peptides against drug-resistant Gram-positive pathogens. Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13517-13522. doi: 10.1073/pnas.1821410116. Epub 2019 Jun 17. PMID: 31209048; PMCID: PMC6613076.
Morwitzer MJ, Tritsch SR, Cazares LH, Ward MD, Nuss JE, Bavari S, Reid SP. Identification of RUVBL1 and RUVBL2 as Novel Cellular Interactors of the Ebola Virus Nucleoprotein. Viruses. 2019 Apr 23;11(4):372. doi: 10.3390/v11040372. PMID: 31018511; PMCID: PMC6521077.
Olson MG, Widner RE, Jorgenson LM, Lawrence A, Lagundzin D, Woods NT, Ouellette SP, Rucks EA. Proximity Labeling To Map Host-Pathogen Interactions at the Membrane of a Bacterium-Containing Vacuole in Chlamydia trachomatis-Infected Human Cells. Infect Immun. 2019 Oct 18;87(11): e00537-19. doi: 10.1128/IAI.00537-19. PMID: 31405957; PMCID: PMC6803327.
Trease AJ, Li H, Spagnol G, Zheng L, Stauch KL, Sorgen PL. Regulation of Connexin32 by ephrin receptors and T-cell protein-tyrosine phosphatase. J Biol Chem. 2019 Jan 4;294(1):341-350. doi: 10.1074/jbc.RA118.003883. Epub 2018 Nov 6. PMID: 30401746; PMCID: PMC6322898.
Wood NA, Chung KY, Blocker AM, Rodrigues de Almeida N, Conda-Sheridan M, Fisher DJ, Ouellette SP. Initial Characterization of the Two ClpP Paralogs of Chlamydia trachomatis Suggests Unique Functionality for Each. J Bacteriol. 2018 Dec 20;201(2): e00635-18. doi: 10.1128/JB.00635-18. Erratum in: J Bacteriol. 2019 Nov 20;201(24): PMID: 30396899; PMCID: PMC6304667.
Xie S, Farmer T, Naslavsky N, Caplan S. MICAL-L1 coordinates ciliogenesis by recruiting EHD1 to the primary cilium. J Cell Sci. 2019 Nov 14;132(22): jcs233973. doi: 10.1242/jcs.233973. PMID: 31615969; PMCID: PMC6899013.
Zhang J, Yang X, Zhou Y, Fox H, Xiong H. Direct contacts of microglia on myelin sheath and Ranvier's node in the corpus callosum in rats. J Biomed Res. 2019 Jun 4;33(3):192-200. doi: 10.7555/JBR.32.20180019. PMID: 30403198; PMCID: PMC6551421.
Zheng L, Li H, Cannon A, Trease AJ, Spagnol G, Zheng H, Radio S, Patel K, Batra S, Sorgen PL. Phosphorylation of Cx43 residue Y313 by Src contributes to blocking the interaction with Drebrin and disassembling gap junctions. J Mol Cell Cardiol. 2019 Jan; 126:36-49. doi: 10.1016/j.yjmcc.2018.11.008. Epub 2018 Nov 15. PMID: 30448479.
2018
Aithal A, Junker WM, Kshirsagar P, Das S, Kaur S, Orzechowski C, Gautam SK, Jahan R, Sheinin YM, Lakshmanan I, Ponnusamy MP, Batra SK, Jain M. Development and characterization of carboxy-terminus specific monoclonal antibodies for understanding MUC16 cleavage in human ovarian cancer. PLoS One. 2018 Apr 30;13(4):e0193907. doi: 10.1371/journal.pone.0193907. PMID: 29708979; PMCID: PMC5927449.
Casey CA, Thomes P, Manca S, Petrosyan A. Giantin Is Required for Post-Alcohol Recovery of Golgi in Liver Cells. Biomolecules. 2018 Nov 16;8(4):150. doi: 10.3390/biom8040150. PMID: 30453527; PMCID: PMC6316505.
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