UNMC_Acronym_Vert_sm_4c
University of Nebraska Medical Center

Tadayoshi Bessho, PhD

Associate Professor, UNMC Eppley Institute for Research in Cancer and Allied Diseases
Research focus: DNA interstrand crosslink repair in mammalian cells

402-559-7018

Tadayoshi Bessho is a faculty member in the UNMC Eppley Institute for Research in Cancer and Allied Diseases. Dr. Bessho joined the University of Nebraska Medical Center in the Summer of 2003. Dr. Bessho received a Ph.D. from the Okayama University in Japan. He did his postdoctoral training at the University of Texas Medical Branch at Galveston and the University of North Carolina at Chapel Hill. Dr. Bessho started his independent career as an assistant professor at the University of Texas Health Science Center at San Antonio, Texas in 2001.

Education
  • Ph.D. (Pharmaceutical Sciences), Okayama University, Okayama, Japan
  • M.Sc. (Pharmaceutical Sciences), Okayama University, Okayama, Japan
  • B.Sc. (Pharmaceutical Sciences), Okayama University, Okayama, Japan
Research

The Bessho lab's focus is to understand the molecular mechanism of DNA repair. DNA repair is essential to maintain genome stability to prevent cancer formation. DNA repair also influences the efficacy of many chemotherapies and radiation therapy that induce DNA damage. Alterations in DNA repair in cancers can be a target for chemotherapy. The goal is to identify a targetable DNA repair gene/pathway in a particular cancer type and define a gene signature to accurately predict the efficacy and selectivity of the treatment.

Recognition
UNMC Distinguished Scientist, 2009