Amar Natarajan, PhD

Professor, Eppley Institute

Courtesy Appointment - Department of Genetics, Cell Biology and Anatomy;
Department of Pharmaceutical Sciences

Co-Leader of Targets Modulators and Delivery Program (TMDP)
Fred & Pamela Buffett Cancer Center

Phone:  402-559-3793
Email: Amar Natarajan

Education

PhD, University of Vermont

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Research Interests

Our research interests are focused on the discovery and development of small molecule inhibitors to perturb disease relevant biomolecules. We are also interested in using these small molecule inhibitors to understand the role of the disease relevant biomolecules in signal transduction. Small molecule inhibitors for these studies are identified and developed from a variety of sources, which include screening chemical libraries, natural products and conformationally constrained mimics. Synthetic chemistry spearheads our research program, however, biology and computational methods are used synergistically in our quest for a better comprehension of the cellular events contiguous to disease relevant proteins.

Selected Publications

Targeting the phosphoprotein binding site on BRCT(BRCA1) / Cbl (TKB)

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Assay development and high throughput screening

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Methods development, synthesis of focused libraries and natural product syntheses

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On the path from bench to bedside – Studies in mouse models

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Group Pictures

Spring 2024

Spring 2021

Dr. Amar Natarajan Lab - May 2021 Farewell Hannah and Sydney

Summer 2019

Dr. Amar Natarajan Lab - Summer 2019 andeep farewell

Summer 2019

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Summer 2018

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Fall 2017

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Winter 2016

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Natarajan Lab Spring 2016

Summer 2015

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Winter 2014

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Summer 2013

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Spring 2012

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Fall 2011

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