Research

NIH AI Research Opportunities 

>> The NIH Common Fund announces the FY2022 funding opportunity for the NIH Director’s Transformative Research Award [commonfund.nih.gov] in the High-Risk, High-Reward Research program [commonfund.nih.gov]. The program provides unique opportunities for creative scientists throughout the nation to pursue highly innovative approaches to address major challenges in any topic within the broad mission of NIH.

NIH especially encourages applications from women and members of groups that are underrepresented in NIH-funded research. Researchers from diverse backgrounds (see NOT-OD-20-031 [grants.nih.gov]), including individuals from underrepresented racial and ethnic groups, individuals with disabilities, individuals from disadvantaged backgrounds, and women are strongly encouraged to work with their institutions to develop applications for this Funding Opportunity Announcement. It encourages applications from the full range of eligible institutions, including those serving primarily underrepresented groups, those that may be less research-intensive, and from all domestic geographic locations. Applications are welcome in all research areas broadly relevant to the mission of NIH. These areas include, but are not limited to, the behavioral, medical, natural, social, applied, and formal sciences. Research may be basic, translational, or clinical. The primary requirements are that the research be highly innovative and have the potential for unusually broad impact.

The Transformative Research Award is piloting an anonymized review process. Applicants should carefully read and follow the instructions in the funding opportunity to ensure responsiveness.

FY2022 NIH Director’s Transformative Research Award (R01 - Clinical Trial Optional): RFA RM-21-017 [grants.nih.gov]

Supports individuals or teams proposing that are inherently risky and untested but have the potential to create or overturn fundamental paradigms.

The High-Risk High-Reward Research Program and other Common Fund programs are managed by the Office of Strategic Coordination, Division of Program Coordination, Planning, and Strategic Initiatives in the NIH Office of the Director, in partnership with the component NIH Institutes, Centers, and Offices. The NIH Common Fund [commonfund.nih.gov] encourages collaboration and supports a series of exceptionally high impact, trans-NIH programs.

The National Institutes of Health (NIH) – “The Nation's Medical Research Agency” – includes 27 Institutes and Centers and is a component of the U. S. Department of Health and Human Services. It is the primary federal agency for conducting and supporting basic, clinical and translational medical research, and it investigates the causes, treatments and cures for both common and rare diseases. For more information about NIH and its programs, visit the NIH website [nih.gov].


 

>> The NIH Common Fund announces the FY2022 funding opportunity for the NIH Director’s New Innovator Award in the High-Risk, High-Reward Research program [commonfund.nih.gov]. The program provides unique opportunities for exceptionally creative scientists to pursue highly innovative approaches to address major challenges in biomedical or behavioral research. Any research topic relevant to the broad mission of NIH is welcome. NIH especially encourages applications from women and members of groups that are underrepresented in NIH-funded research.

2022 NIH Director's New Innovator Award (DP2 - Clinical Trial Optional): RFA-RM-21-016 [grants.nih.gov]

Supports exceptionally creative early career scientists proposing unusually innovative and high-impact projects. Individuals from diverse backgrounds and from the full spectrum of eligible institutions in all geographic locations are strongly encouraged to apply to this Funding Opportunity Announcement. In addition, applications in all topics relevant to the broad mission of NIH are welcome, including, but not limited to, topics in the behavioral, social, biomedical, applied, and formal sciences and topics that may involve basic, translational, or clinical research.

 See the New Innovator Award website [commonfund.nih.gov] for more information, including FAQs, an application guide with sample applications, and past webinar (a new webinar will be forthcoming).

The High-Risk High-Reward Research Program and other Common Fund programs are managed by the Office of Strategic Coordination, Division of Program Coordination, Planning, and Strategic Initiatives in the NIH Office of the Director, in partnership with the component NIH Institutes, Centers, and Offices. The NIH Common Fund [commonfund.nih.gov] encourages collaboration and supports a series of exceptionally high impact, trans-NIH programs.

The National Institutes of Health (NIH) – “The Nation's Medical Research Agency” – includes 27 Institutes and Centers and is a component of the U. S. Department of Health and Human Services. It is the primary federal agency for conducting and supporting basic, clinical and translational medical research, and it investigates the causes, treatments and cures for both common and rare diseases. For more information about NIH and its programs, visit the NIH website [nih.gov].


 

>> The NIH has issued a Research Opportunity Announcement (ROA) for Data Generation Projects for the Bridge to Artificial Intelligence (Bridge2AI) Program (OT2) [commonfund.nih.gov]. This ROA is soliciting Data Generation Projects to create flagship datasets based on ethical principles, associated standards and tools, and skills and workforce development to address biomedical and behavioral research grand challenges that require artificial intelligence and machine-learning (AI/ML) analysis. The Bridge2AI program plans to support the formation of teams richly diverse in perspectives, backgrounds, and academic and technical disciplines. This ROA requires a Plan for Enhancing Diverse Perspectives (PEDP) [commonfund.nih.gov]--a summary of strategies to advance the scientific and technical merit of the proposed project(s) through inclusivity. Visit the Bridge2AI Program Resources [commonfund.nih.gov] page,

Building Diverse Teams [commonfund.nih.gov] page, and Program FAQs [commonfund.nih.gov] for additional information on building diverse teams and for PEDP guidance. 

To facilitate team building across communities and ensure responsiveness of proposals, NIH strongly encourages potential proposers to participate in the Grand Challenge Team Building Activities taking place in June 2021, please save the date for these upcoming events: 

Bridge2AI Program Town Hall
June 9, 2021
2:00-3:30pm ET

 

Bridge2AI Data Generation Project Module Microlabs
June 14, 16, and 18, 2021
2:00-4:00pm ET each day

 

Bridge2AI Grand Challenge Team Building Expo
June 23, 2021
11:00am-5:00pm ET


 

Published Academic Journals 

Achieving Data Liquidity: Lessons Learned from Analysis of 38 Clinical Registries (The Duke-Pew Data Interoperability Project. Tcheng JE, Drozda JP, Gabriel D, Heath A, Wilgus RW, Williams M, Windle TA, Windle JR.AMIA Annu Symp Proc. 2020 Mar 4;2019:864-873. eCollection 2019.PMID: 32308883 Free PMC article.

Westcott RJ, Tcheng JE. Artificial Intelligence and Machine Learning in Cardiology. JACC Cardiovasc Interv. 2019 Jul 22;12(14):1312-1314. doi: 10.1016/j.jcin.2019.03.026. Epub 2019 Jun 26. PMID: 31255559.

Windle, J. R., & Windle, T. A. Electronic health records and the quest to achieve the “triple aim”. Journal of the American College of Cardiology. Volume. 65. No 18, 2015