Contributor: Dr. Tylka

A 73-year-old Caucasian male presents with a lesion of the right lateral tongue.

History of the lesion:

  • Duration: Unknown (Has a history of recurrent white plaque of varying thickness on the right lateral tongue. Previous biopsy was diagnosed as mild dysplasia and treated by laser ablation.)
  • Oral examination: White plaque on the right lateral tongue measuring approximately 2 x 3 cm. Some induration was noted in the anterior superior area.
Differential diagnoses should include:

Next course of action:

If the histology of the lesion is as shown, your clinical diagnosis is: