Iman M. Ahmad, PhD

Assistant Professor

Department of Medical Imaging and Therapeutic Sciences     Iman Ahmad
University of Nebraska Medical Center
984545 Nebraska Medical Center
Omaha, NE 68198-4545
402-559-6911
Email

Academic Appointments:
Assistant Professor, 2013

Degrees/Certifications:
B.Sc., Diagnostic Radiologic Technology, Kuwait University, Kuwait City, Kuwait, 1989
Ph.D., Free Radicals and Radiation Biology, University of Iowa, Iowa City, Iowa, USA, 2003

Primary Teaching Responsibilities:
MITS 414R Health Physics
MITS 438N Advanced Radiation Biology
MITS 413R Radiographic Contrast Media
MITS 313R Radiologic Technology II
MITS 350R Radiographic Pathology I
MITS 355R Radiographic Pathology II

Research Experience:
Visiting Scientist: University of Cincinnati (July-Sept. 2005)
Working on the oxidative stress induced by pyocyanin in A549 and HBE cells.
The study includes the study of expression of Glutathione (total and mitochondrial), HO-1, Thioredoxin, and HIF-1alpha.

Visiting Scientist: University of Iowa (June-Aug. 2006)
Working on 2-deoxyglucose-induced sensitization to p53 induced cell death in prostate cancer cells.

Visiting Scientist: University of Iowa (June-Aug. 2007)
Working on radiation therapy, metabolic oxidative stress, and cancer biology project.

Visiting Scientist: University of Iowa (June-Aug. 2008)
Working on cancer therapy related projects that involve imaging responses to 2-deoxyglucose-induced radiosensitization and radiation-induced genomic instability.

Research Responsibilities:
Conduct research in ongoing redox biology studies using state-of-the art techniques to measure levels of antioxidants and oxidants in biological samples; involved in designing and optimizing experimental protocols; and writing collaborative research grants.

Publications (last 5 years):
Kalen AL, Ahmad IM, Abdalla MY, O’Malley YQ, Goswami PC, Sarsour EH. MnSOD and Cyclin B1 Coordinate a Mito-Checkpoint
during Cell Cycle Response to Oxidative Stress. Antioxidants, 6, 92; 2017 doi:10.3390/antiox6040092 PDF

Dickinson JD, Sweeter JM, Warren KJ, Ahmad IM, De Deken X, Zimmerman MC, Brody SL. Autophagy regulates DUOX1 localization and superoxide production in airway epithelial cells during chronic IL-13 stimulation. Redox Biol. 2017 Sep 22;14:272-284. doi: 10.1016/j.redox.2017.09.013. [Epub ahead of print] PMID: 28982074 Free PMC Article

Bajbouj K, Shafarin J, Abdalla MY, Ahmad IM, Hamad M. Estrogen-induced disruption of intracellular iron metabolism leads to oxidative stress, membrane damage, and cell cycle arrest in MCF-7 cells. Tumor Biology, Oct: 1-12, 2017. DOI: 10.1177/1010428317726184 PDF

Ahmad IM, Temme JB, Abdalla MY, Zimmerman MC. Redox status in workers occupationally exposed to long-term low levels of ionizing radiation: A pilot study. Redox Rep. 2016 Jan 28. [Epub]

Saraswathi V, Ganesan M, Perriotte-Olson C, Manickam DS, Westwood RA, Zimmerman MC, Ahmad IM, Desouza CV, Kabanov AV. Nanoformulated copper/zinc superoxide dismutase attenuates vascular cell activation and aortic inflammation in obesity. Biochem Biophys Res Commun. 2016 Jan 15;469(3):495-500. doi: 10.1016/j.bbrc.2015.12.027. Epub 2015 Dec 12.

Case AJ, Agraz D, Ahmad IM, Zimmerman MC. Low-Dose Aronia melanocarpa Concentrate Attenuates Paraquat-Induced Neurotoxicity. Oxid Med Cell Longev. 2016;2016:5296271. doi: 10.1155/2016/5296271. Epub 2015 Dec 6.

Mustafa EH, Mahmoud HT, Al-Hudhud MY, Abdalla MY, Ahmad IM, Yasin SR, Elkarmi AZ, Tahtamouni LH. 2-deoxy-D-Glucose Synergizes with Doxorubicin or L-Buthionine Sulfoximine to Reduce Adhesion and Migration of Breast Cancer Cells. Asian Pac J Cancer Prev, 16 (8), 3213-3222, 2015.

Abdalla MY, Ahmad IM, Switzer B, Britigan BE. (2015) Induction ofhemeoxygenase-1 contributes to survival of Myco-bacterium abscessus in human macrophages-like THP-1 cells. Redox Biology. 4:328-339.

Tayyem RF*, Ahmad IM*, Shehadah I, Bani-Hani K, Al-Jaberi T , Al-Nusairr M. Glutathione, Vitamin D and Antioxidant Status in the Blood of Patients with Colorectal Cancer: A Pilot Study. (2015) Pakistan Journal of Nutrition. 14 (1): 13-17.

Savalia K, Manickam DS, Rosenbaugh EG, Tian J, Ahmad IM, Kabanov AV, Zimmerman MC. Neuronal uptake of nanoformulated superoxide dismutase and attenuation of angiotensin II-dependent hypertension after central administration. Free Radical Biology and Medicine. 73 (2014) 299-307.

Ahmad IM, Abdalla MY. (2012) Mitochondria-Mediated Oxidative Stress and Cancer Therapy. In: Spitz DR. et al. (eds.). Oxidative Stress in Cancer Biology and Therapy, Oxidative Stress in Applied Basic Research and Clinical Practice. Springer Science and Business Media, LLC; Part 1, pp 3-19.

Abdalla MY, Mathahs MM, Ahmad IM. (2012) Protective Role of Heme Oxygenase-1 in Liver. Biologia. 67(4): 623-628.

Abdalla MY, Mathahs MM, Ahmad IM. (2012) Reduced heme oxygenase-1 expression in steatotic livers infected with hepatitis C virus. European Journal of Internal Medicine 23(7): 649-655.

Abdalla MY, Hassan IM, Mustafa NH, Tahtamouni LH, Ahmad IM. (2011) Total body glutathione depletion induces oxidative stress and disrupts the immune function in mice. Toxicological & Environmental Chemistry. 93(1): 157-170.

Ahmad IM, Britigan BE, Abdalla MY. (2011) Oxidation of thiols and modification of redox-sensitive signaling in human lung epithelial cells exposed to Pseudomonas pyocyanin. Journal of Toxicology and Environmental Health, Part A. 74:43-51.

Abdalla MY, Fawzi M, Al-Maloul SR, El-Banna N, Tayyem RF, Ahmad IM. (2011) Increased Oxidative Stress and Iron Overload in Jordanian B Thalassemic Children. Hemoglobin. 35(1):67–79.

Fath MA, Ahmad IM, Smith CJ, Spence J, Spitz DR. (2011) Enhancement of carboplatin-mediated lung cancer cell killing by simultaneous disruption of glutathione and thioredoxin metabolism. Clinical Cancer Research. 17(19):6206-17.