Brain Tumor Mini Summit

12:00 – 1:15pm 

Welcome & Summit Overview Sidharth Mahapatra, MD, PhD, Co-Leader, Brain Tumor Working Group, Associate Professor, Pediatrics, UNMC

Grand Rounds featuring Amar Gajjar, MD, Scott and Tracie Hamilton Endowed Chair in Brain Tumor Research, St. Jude Children's Research Hospital

Medulloblastoma – A Compendium of Four Molecular Distinct Diseases 

1:15-1:30pm 

Q&A 

1:30-3:45pm

Brain Tumor Working Group Presentations

David Doss, MD/PhD Student, Creighton University 

(Dr. Sidharth Mahapatra lab) 

Nortriptyline: a Repurposable Adjuvant to Chemotherapy in Group 3 Medulloblastomas That Triggers Apoptosis by Inducing Mitochondrial Dysfunction 

Aditya Gupta, Graduate Research Assistant, Pharmaceutical Science 

(Dr. Ram Mahato lab) 

ApoE Peptide-targeted Delivery of Volasertib Loaded Lipid Nanoparticles Sensitizes Medulloblastoma to Radiation Therapy in Mice   

Matthew White, MD, Professor, Radiology 

High Resolution White Matter Tractography 

Angie Rizzino, PhD, Professor, Eppley Institute for Research in Cancer and Allied Diseases 

SOX2 Controls Medulloblastoma Cell Proliferation by Modulating c-MYC Expression 

Short Break 

Allison Guild, DO, Fellow, Pediatric Hematology/Oncology 

Evaluating the Association Between Pollution and Molecular Subtyping of Pediatric Gliomas  

Afshin Salehi, MD, MS, Assistant Professor, Neurosurgery 

Repurposing Vortioxetine for H3K27M-Midline Glioma 

Alfred Bothwell, PhD, Professor, Pathology, Microbiology and Immunology 

Does Trogocytosis also Contribute to Pediatric and Adult Brain Cancer? 

Chi (Kevin) Zhang, MD, PhD, Associate Professor, Radiation Oncology 

Exosomal miRNAs under Androgen Receptor Regulation in Glioblastoma  

3:45-4:00pm 

Conclude Summit