University of Nebraska Medical Center

Pediatric Pharmacology Research Unit

The Pediatric Pharmacology Research Unit translates pediatric pharmacokinetic, pharmacodynamic and pharmacogenomic research into clinical practice. As a collaboration among the UNMC Colleges of Pharmacy and Medicine, Children’s Hospital & Medical Center and the Child Health Research Institute, the goal of the program is to work in partnership to study and optimize medication therapy in pediatric patients.
side of Children's hospital Hubbard building

The research unit works within the Pediatric Clinical Pharmacology Program, along with a Clinical Pharmacology Consult Service and Pharmacogenomics Clinic. The research unit is capable of developing nontraditional drug assays, pharmacokinetic/pharmacodynamics modeling and clinical trial design and support. The research unit is currently working with clinicians, academic researchers, federal/industry sponsors and private donors to better understand the relationship between pharmacology and ontogeny in the pediatric patient population.

Individuals interested in clinical consultation or exploring partnerships with the research unit are encouraged to contact Director Christopher Shaffer, PharmD, PhD at cshaffer@unmc.edu or clshaffer@childrensnebraska.org.

Follow the research unit on Twitter: @unmc_ppru

Our Team

Assistant Professor, Department of Pharmacy Practice and Science, UNMC College of Pharmacy


Christopher L. Shaffer, PharmD, PhD

Associate Professor, Department of Pharmacy Practice and Science College of Pharmacy


Anthony Podany, PharmD

Assistant Professor, Department of Pharmacy Practice and Science


Sean N. Avedissian, PharmD
Munroe Meyer Building

MMI Pharmacogenetics Clinic

UNMC Genetic Medicine and the Pediatric Clinical Pharmacology Program have partnered to provide the MMI Pharmacogenetics Clinic. The clinic is a multidisciplinary team of geneticists, genetic counselors, and clinical pharmacologists who examine the relationship between genetics and pharmacology to recommend a personalized medicine approach for patients and clinicians. Patients can be seen inpatient or outpatient.

View of Children's Hubbard Building

Pharmacology Consult Service

The Pediatric Clinical Pharmacology Consult Service is a clinical consult service that can assist clinicians and patients that have suffered unanticipated therapeutic toxicities or treatment failures. The formal consult will investigate potential causative factors for toxicity or therapeutic failures, including the use of pharmacogenomic testing.