The Fred & Pamela Buffett Cancer Center
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University of Nebraska Medical Center

Guide To Enroll in a Clinical Trial

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Deciding to join a clinical trial is a personal choice, different for every patient. If you take part in a clinical trial at the Fred & Pamela Buffett Cancer Center, our team will guide you and your family through the entire process.  

Find a Cancer Clinical Trial

Things to Consider Before Joining a Clinical Trial  

Before joining a clinical trial, it's important to ask questions to your doctor or trial team and get the information you need. Below are some key questions you might want to ask: 

  • What is the purpose of this study?  
  • What are the possible benefits and risks?  
  • What other treatment options do I have?  
  • What tests and procedures will I need?  
  • How will this affect my daily life?  
  • How much will this cost, and what will my insurance cover?  
  • What financial or travel help is available? (if needed)  

Steps to Enroll:  

  1. Talk with your doctor about whether a trial might be right for you. They are often the best resource to point you to ongoing clinical trials.  
  2. Search for trials on ClinicalTrials.gov, NCI, or Fred and Pamela Buffett Cancer Center database, or ask your care team.  
  3. Talk with the study team (the clinical trial coordinator) to learn more about a specific trial. 
  4. Complete screening tests to see if you qualify.  
  5. Review all information carefully before making your decision.  
  6. Complete informed consent if you choose to join.  

Understanding Your Safety and Rights  

Informed Consent: Before joining a clinical trial, the research team will explain what the trial is about and what you'll need to do. They will discuss the possible benefits and risks. They will answer your questions to make sure you understand what you agree to before you sign anything. Take the time to think it over and discuss it with people you trust. You can also leave the trial at any time if you change your mind.  

Safety Monitoring: When you take part in a clinical trial, there are strict rules in place to protect your safety and well-being. Groups like Institutional Review Boards (IRBs) and the U.S. Food and Drug Administration (FDA) make sure clinical trials are safe.  

Signing Up for a Clinical Trial  

To join a clinical trial, you must meet specific requirements (called eligibility criteria). These may include your type of cancer, cancer stage, age, treatment history, and other health conditions.   

Understanding Cost, Insurance and Support for Clinical Trials  

Many clinical trials are sponsored by organizations such as cancer centers, drug companies, government agencies, or non-profit groups. These sponsors help cover study costs. However, coverage can vary. It's important to ask the study team about the costs included and any expenses you may need to pay.