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The Fred & Pamela Buffett Cancer Center

- Leadership Overview
- Director's Message
  Read a message from Joann Sweasy, PhD, director of the Fred & Pamela Buffett Cancer Center.
- About the Center
  Learn about the mission and vision of the Fred & Pamela Buffett Cancer Center.
- Outreach Overview
- Mission
  The Community Outreach and Engagement Office aims to reduce overall cancer burden and eliminate cancer-related health disparities in its catchment area.
- Community Advisory Board
  This board advises on the direction of cancer center research, dissemination of evidence from ongoing research activities, and policy recommendations.
- Speaker's Bureau
  The Fred & Pamela Buffett Cancer Center Speakers Bureau provides resources to community groups across Nebraska including experts to give presentations on cancer-related topics.
- Resources
  The Community Outreach and Engagement Office provides such resources as videos, infographics, reports and community needs assessments.
- Our Team
  Find members of the Community Outreach and Engagement Office team.
- Nebraska Breast Health Navigation Program
  This program is working to eliminate barriers for breast cancer survivors, using trained volunteers called Lay Patient Navigators who provide peer-to-peer support.
- Research Overview
- Cancer Biology Program
  Learn about our work to understand the fundamental mechanisms that underlie cancer initiation and progression in order to find new biomarkers and therapeutic targets.
- Gastrointestinal Cancer Program
  We are working to better understand these cancers, to identify new tools for their management, and to develop new therapies.
- Targets, Modulators and Delivery Program
  We are developing and delivering small molecules to modulate validated cancer targets as eventual cancer therapeutics.
Patient Care
Training & Education

— The Fred & Pamela Buffett Cancer Center — Research — Gastrointestinal Cancer Program

Gastrointestinal Cancer Program

Our Gastrointestinal Cancer Program is focused on:

Understanding the pathogenesis and pathophysiology of gastrointestinal cancers.
Identifying and validating new diagnostic and prognostic tools for gastrointestinal cancer management.
Developing new therapeutic options for patients with gastrointestinal malignancies.

Leaders

Jennifer Black, PhD

Professor, UNMC Eppley Institute for Research in Cancer and Allied Diseases
Research focus: Protein kinase C and PP2A signaling in colon, pancreas and endometrial cancer; targeting translational control in tumors

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Phone: 402-559-6097

Jennifer Black

Chi Lin, MD, PhD, MS

Vice Chair of Research, UNMC Department of Radiation Oncology
Professor

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Dr. Chi LIn

Themes and Goals

The Gastrointestinal Cancer Program is organized into three themes and goals:

Mechanisms of Gastrointestinal Tumorigenesis
- Understand basis mechanisms of gastrointestinal tumorigenesis and identify abnormalities that may serve as novel biomarkers or therapeutic targets.
Biomarkers
- Develop and validate biomarkers for gastrointestinal cancer detection, prognosis and risk stratification.
Novel Treatment Approaches
- Explore novel treatment approaches for gastrointestinal cancers in preclinical models and clinical trials.