Targets, Modulators, and Delivery Program

This program is developing and delivering small molecules to modulate validated cancer targets as eventual cancer therapeutics.

The program brings together investigators with complementary expertise to facilitate translation of basic science discoveries across the bench-to-bedside continuum within the research programs of the Eppley Institute and its partner, the Fred & Pamela Buffett Cancer Center. 

Areas of expertise include:

• Cancer target validation and characterization
• Medicinal chemistry
• Pharmacology
• Nanodelivery

The program has led efforts to establish several shared resources, including the Synthetic and Medicinal Chemistry Resource, the Computational Chemistry Resource, and the Translational Drug Development Resource.