University of Nebraska Medical Center

Yazen Alnouti, PhD



Yazen Alnouti
Research Activities/Interests

Research in Dr. Alnouti's laboratory is involved in the multidisciplinary area of drug metabolism and pharmacokinetics (DMPK). His research focuses on the application of Bioanalytical Chemistry, in vitro and in vivo animal models to support ADMET (absorption, distribution, metabolism, excretion, and toxicity) and pharmacokinetic (PK) studies. This is a technique-driven enterprise; therefore expertise in liquid chromatography-mass spectrometry (LC-MS) is heavily used in his research.

Another area of interest in Dr. Alnouti's laboratory is the discovery of biomarkers for hepato-biliary diseases based on bile acid metabolism by sulfation, a phase II metabolic pathway.

Teaching Activities
At the professional level, Dr. Alnouti lectures in the areas of Drug Metabolism and Pharmacokinetics in the "Introduction to Pharmaceutical Sciences" and "Pharmaceutical Sciences II & III" courses. At the graduate level, Dr. Alnouti provides lectures in "Advanced Pharmacokinetics and Pharmacodynamics" and the "Quantitative Pharmaceutical Analysis" courses.