Courtney V. Fletcher, PharmD

ProfessorDr. Courtney Fletcher

Department of Pharmacy Practice and Science
College of Pharmacy
University of Nebraska Medical Center
986145 Nebraska Medical Center
Omaha, NE 68198-6145
402-559-9249 (Office)
402-559-5673 (Fax)

Recent Publications:

  1. Swindells S, Ramchandani R, Gupta A, Benson CA, Leon-Cruz J, Badal-Faesen S, Juste MAJ, Lama J, Valencia J, Omoz-Oarhe A, Supparatpinyo K, Masheto G, Mohapi L, Escada RO, Mngqibisa R, Dadabhai S, Severe P, Hakim J, Kanyama C, Langat D, Moran L, Anderson J, Fletcher CV, Nuermberger E, Chaisson RE. One month rifapentine and isoniazid to prevent tuberculosis in HIV-infected individuals: the BRIEF TB/A5279 Trial.* Submitted.
  2. Diacon A, Miyahara S, Dawson R, Sun X, Hogg E, Donahue K, De Jager V, Fletcher CV, Hafner R, Swindells S, Bishai W. The essentiality of isoniazid during the first 14 days of tuberculosis therapy.* Submitted.
  3. Rothenberger M, Nganou-Makamdop K, Kityo C, Ssali F, Chipman JG, Beilman GJ, Hoskuldsson T, Anderson J, Jasurda J, Schmidt TE, Calisto SP, Pearson H, Reimann T, David C, Perky K, Southern P, Wietgrefe S, Helgeson E, Reilly C, Haase AT, Douek DC, Fletcher CV, Schacker TW. Impact of integrase inhibition compared to non-nucleoside inhibition on HIV virus reservoirs in lymphoid tissues.* Journal of the Acquired Immunodeficiency Syndrome in press.
  4. Couturier J, Winchester LC, Suliburk JW, Wilkerson GK, Podnay AT, Agarwal N, Chua CYX, Nehete PN, Nehete BP, Grattoni A, Sastry J, Fletcher CV, Lake JE, Balasubramanyan A, Lewis DE. Adipocytes impair efficacy of antiretroviral therapy. * Antiviral Research 2018; 154: 140- 48. PMCID: PMC5955795; DOI: 10.1016/j.antiviral.2018.04.002
  5. Shetty RD, Scarsi KK, Byrareddy S, Zhen Y, Fletcher CV, Podany AT. Highly precise droplet digital PCR assay to measure RPP30 copies for normalizing cell associated antiretroviral drug concentrations in human and non-human primate models of HIV infection. * Scientific Reports 2018; Feb 26;8(1):3626. PMID: 29483619; PMCID: PMC5827666; DOI: 10.1038/s41598-018- 21882-0
  6. Cirrincione LR, Penchala SD, Scarsi KK, Podany AT, Winchester LC, Back DJ, Khoo SH, Fletcher CV, Siccardi M, Else LJ. Development, validation and utilization of a highly sensitive LC-MS/MS method for quantification of levonorgestrel released from a subdermal implant in human plasma.* Journal of Chromatography B 2018; 1084:106-112. Doi: 10.1016/jchromb.2018.03.023 ; PMCID: PMC5892837
  7. Gandhi M, Gandhi R, Stefanescu A, Bosch RJ, Cyktor JC, Horng H, Louie A, Phung N, Eron JJ, Hogg E, Macatangay BJC, Hensel C, Fletcher CV, mellors JW, McMahon DK. Cumulative antiretroviral exposure in hair is not associated with measures of HIV persistence or inflammation among individuals on suppressive therapy. * Journal of Infectious Diseases 2018; 218:234-8.* PMCID: PMC6009579
  8. Roberts O, Rajoli RKR, Back DJ, Owen A, Darin KM, Fletcher CV, Lamorde M, Scarsi KK, Siccardi M. Physiologically-based pharmacokinetic modeling prediction of the effects of dose adjustment in drug-drug interactions between levonorgestrel contraceptive implants and efavirenz-based antiretroviral therapy. * Journal of Antimicrobial Chemotherapy 2018; Apr 1;73(4):1004-12. doi: 10.1093/jac/dkx515. PMCID: PMC5890694
  9. Rothenberger M, Wagner JE, Haase A, Richman D, Grywacz B, Strain M, Lada S, Estes J, Fletcher CV, Podany AT, Anderson J, Schmidt T, Wietgrefe S, Schacker T, Verneris MR. Transplantation of partially HLA matched, CCR5d32 homozygous umbilical cord blood in a patient with acute lymphoblalstic leukemia and human immunodeficiency virus infection. * Open Forum Infectious Diseases 2018; May 5(5): doi: 10.1093/ofid/ofy090. PMCID: PMC5965100
  10. Podany AT, Bares SH, Havens J, Shetty RD, O’Neill J, Lee S, Fletcher CV, Swindells S, Scarsi KK. Plasma and intracellular pharmacokinetics of tenofovir in patients switched from tenofovir disoproxil fumarate to tenofovir alafenamide. * AIDS 2018; 32(6):761-65. doi: 10.1097/QAD.0000000000001744. PMCID: PMC5854526