The Fred & Pamela Buffett Cancer Center

Patient Care
- Research Overview
- - Membership Directory
    Search a listing of full members of the Fred & Pamela Buffett Cancer Center, as well as directories of members by research program.
  - Membership Criteria
    Learn about the criteria for becoming a member of the Fred & Pamela Buffett Cancer Center.
  - Become a Member
    Apply for membership in the Fred & Pamela Buffett Cancer Center by submitting a short form.
- - Shared Resources
    The Fred & Pamela Buffett Cancer Center is home to state-of-the-art facilities and provides support to shared resources at UNMC.
  - UNMC Cores and Shared Resources
    Researchers also have access to shared resources through the UNMC Office of the Vice Chancellor for Research.
  - Request Research Space
    Complete this form to request research space.
  - Research Funding Opportunities
    NCI-designated Fred & Pamela Buffett Cancer Center supports Principal Investigators through pilot grants and seed funding to explore novel research ideas and engage in team science projects that address critical cancer care and treatment challenges.
- - Cancer Biology Program
    The Fred & Pamela Buffett Cancer Center Cancer Biology Program represents a long-standing commitment to cancer mechanisms-focused research.
  - Translational Cancer Research Program
    This program develops and delivers small molecules to modulate validated cancer targets as eventual cancer therapeutics.
  - Cancer Prevention & Control Program
    This program aims at identifying and understanding the factors influencing cancer risk, with a special emphasis on disparities and rural populations in the catchment area.
- - Registries
    View registries that are currently enrolling subjects through iCaRe2.
  - Information for Patients
    Participation helps researchers understand specific cancer types, determine risk factors, advance treatment for patients and discover cancer prognostic markers.
  - Information for Researchers
    iCaRe2 aims to foster clinical and epidemiological studies and accelerate the secondary use of cancer and health related data for translational research.
  - Information for Sponsors
    Your gift will support the continuous system growth and improve strides in personalized medicine, diagnosis, treatment and prevention of cancer.
- Community Outreach Overview
- Mission
  We are committed to reducing the cancer burden across Nebraska through strong partnerships, community-driven initiatives, and programs informed by community needs and priorities.
- Community Advisory Board
  This board advises on the direction of cancer center research, dissemination of evidence from ongoing research activities, and policy recommendations.
- Speaker's Bureau
  The Fred & Pamela Buffett Cancer Center Speakers Bureau provides resources to community groups across Nebraska including experts to give presentations on cancer-related topics.
- Resources
  The Community Outreach and Engagement Office provides such resources as videos, infographics, reports and community needs assessments.
- Our Team
  Find members of the Community Outreach and Engagement Office team.
- Training & Education Overview
- Upper Midwest Emerging Scholars Exchange Program
  Learn about a new opportunity for Early Stage Investigators to share their research at peer institutions.
- Leadership Overview
- Director's Message
  Read a message from Joann Sweasy, PhD, director of the Fred & Pamela Buffett Cancer Center.
- About the Center
  Learn about the mission and vision of the Fred & Pamela Buffett Cancer Center.

Pathology Shared Resource

Pathology

As a shared research resource supported by the Fred & Pamela Buffett Cancer Center (FPBCC) the Pathology Tissue Science Facility (TSF) and the Institutional Biospecimen Bank supports the research community at the UNMC for studies on animal and human tissues.

Pathology Shared Resource Specific Aims:

Provide comprehensive tissue resources, histology, immunohistochemistry and digital pathology services.
Maximize the effectiveness of our resources by training and mentoring users.
Support long-term sustainability of core services through modernization and innovation.
Provide tissue samples from paraffin, frozen, and autopsy sources

Equipment:

Ventana Discovery Ultra-IHC

Leica CM1860-Cryostat

Tissue-Tek Prisma/Glas-Automatic stainer/Coverslipper

LeicaAperio CS2-Bright field scanner

Services:

Comprehensive Histology

Multiplex Immunohistochemistry

Assay Development

Tissue Microarray Construction

Whole Slide Brightfield Digital Imaging

User Support, Training and Equipment

Find more information on services, pricing, and request form.

Tissue Science Facility

Institutional Biospecimen Bank

Impact

Pathology

The Pathology Shared Resource is located in Durham Research Center I and at the cancer center, where 80% of FPBCC members are based, providing them with easy access.

The collaboration between the Tissue Science Facility (TSF) and the Institutional Biospecimen Bank supports basic, clinical, and translational research through easy access to tissue samples. The Institutional Biospecimen Bank consists of FFPE, flash-frozen, live frozen, and cancer cells lines generated from various neoplastic and non-neoplastic diseases. Additionally, blood, serum and plasma samples are available. These tissues are obtained from patients who have consented scientists to use their material for research purposes.

The Tissue Science Facility (TSF) provides comprehensive research histology lab services for processing human and mouse tissue, paraffin-embedding, and sectioning. The TSF provides digital slide scanning and automated immunohistochemistry.

Co-Directors

Kurt W. Fisher, MD, PhD

Co-Director, Pathology Shared Resource

Dinesh Pradhan, MD

Co-Director, Pathology Shared Resource