Operational Director of Bioinformatics and Systems Biology Core

Assistant Professor
Dept. of Genetics, Cell Biology & Anatomy

Education:
PhD, Biomedical Sciences, Creighton University, 2007
BS, Biochemistry and Molecular Biology, Hunan Normal University, 2001

Contact:
Phone: (402) 559-2083
Fax: (402) 559-5942
Email: peng.xiao@unmc.edu

Mailing Address:
6011 Durham Research Center
985145, Nebraska Medical Center
Omaha, NE 68198-5145

Recent publications:

• Cao Z, Moore BT, Wang Y, Peng XH, Lappe JM, Recker RR, Xiao P.MiR-422a as a potential cellular microRNA biomarker for postmenopausal osteoporosis. PLoS ONE 2014. 9:e97098.
• Moore BT, Xiao P. MiRNAs in bone diseases. MicroRNA 2013. 2:20-31.
• Wang Y, Moore BT, Peng XH, Xiao P. Epigenetics and hematopoietic stem or progenitor cells. Hum Genet & Embry: Curr Res 2012. S2:004.
• Wang Y, Li L, Moore BT, Peng XH, Fang X, Lappe JM, Recker RR, Xiao P. MiR-133a in human circulating monocytes: a potential biomarker associated with postmenopausal osteoporosis. PLoS ONE 2012. 7:e34641.
• Ma DJ, Li Y, Akhter M, Zhao YC, Xiao J, Heckford B, Swanson PC, Cullen D, Xiao P, Lappe JM, Recker, RR, Xiao GG. Smoke-induced signal molecules in bone marrow cells of Lrp5 genetically-engineered mice. J Proteom Res 2012. 11:3548-3560.
• Chen XD*, Xiao P*, Lei SF, Liu YZ, Guo YF, Deng FY, Tan LJ, Zhu XZ, Chen FR, Recker, RR, Deng HW. Gene expression profiling in monocytes and SNP association suggest the importance of STAT1 gene for osteoporosis in both Chinese and Caucasians. J Bone Miner Res 2010; 25:339-355. (*: equal contribution).
• Xiong DH, Liu XG, Guo YF, Tan LJ, Wang L, Sha BY, Tang ZH, Pan F, Yang TL, Chen XD, Lei SF, Yerges LM, Zhu XZ, Wheeler VW, Patrick AL, Bunker CH, Guo Y, Yan H, Pei YF, Zhang YP, Levy S, Papasian CJ, Xiao P, Lundberg YW, Recker RR, Liu YZ, Zmuda JM, Deng HW. Genome-wide association and follow-up replication studies identified ADAMTS18 and TGFBR3 as bone mass candidate genes in different ethnic groups. Am J Hum Genet 2009; 84:388-398.
• Yan H, Liu YJ, Zhou Q, Xiao P, Recker RR, Deng HW. Comparison of whole genome linkage scans in premenopausal and postmenopausal women: no bone-loss-specific QTLs were implicated. Osteoporos Int 2009; 20:771-777.
• Xiao P, Chen Y, Jiang H, Liu YZ, Yang TL, Pan F, Tang ZH, Larson JA, Lappe JM, Recker RR, Deng HW. In vivo genome-wide expression study on human circulating B cells suggests a novel ESR1 and MAPK3 network for postmenopausal osteoporosis. J Bone Miner Res 2008; 23:644-654.

Presentations, abstracts:

• Wang Y, Moore B, Peng XH, Fang X, Lappe MJ, Recker RR, Xiao P. MiR-133a and MiR-422a in human circulating monocytes are potential microRNA biomarkers underlying postmenopausal osteoporosis. (the 62^nd American Society of Human Genetics (ASHG) Annual Meeting, November 2012, #3081W)
• Wang Y, Moore B, Peng XH, Fang X, Lappe MJ, Recker RR, Xiao P. MiR-422a in human circulating monocytes is a potential microRNA biomarker underlying postmenopausal osteoporosis. (the 34^th American Society of Bone and Mineral Research (ASBMR) Annual Meeting, October 2012, #SU0278)
• Wang Y, Ling L, Moore B, Peng XH, Fang X, Lappe MJ, Recker RR, Xiao P. MiR-133a in human circulating monocytes: a potential biomarker associated with postmenopausal osteoporosis. (the ASBMR Topical Meeting on Bone and Skeletal Muscle Interactions, July 2012, #P56, ASBMR Young Investigator Award to Wang Yang)
• Hanumanthu VS, Li L, Peng XH, Wang Y, Recker RR, Xiao P. Functional genomic study on circulating B cells underlying defects in bone quality in postmenopausal Caucasian women. (The 61^st ASHG Annual Meeting, October 2011, #808F).
• Zhang ZJ, Chen XD, Gao G, Deng HW, Recker RR, Xiao P. MicroRNA profiling study in human circulating monocytes identified the significance of miR-151 in the etiology of osteoporosis. (The 31^st ASBMR Annual Meeting, September 2009, #1137, ASBMR Young Investigator Award to Peng Xiao, Oral Presentation).
• Gao G, Chen XD, Deng HW, Recker RR, Xiao P. Human microRNA miR-181b in B cells was related with the etiology of osteoporosis. (The 31^st ASBMR Annual Meeting, September 2009, #MO0320).
• Chen XD, Sun LG, Recker RR, Deng HW, Xiao P. Expression profiling study in human B cells identified novel miR181b, miR-7, and miR-627 microRNAs underlying osteoporosis. (The 58^th ASHG Annual Meeting, November 2008, #931).
• Sun LG, Chen XD, Recker RR, Deng HW, Xiao P. Expression profiling study on human monocytes identified novel microRNAs: miR-126, miR-151 and miR-152 for osteoporosis. (The 58^th ASHG Annual Meeting, November 2008, #933).
• Xiao P, Chen XD, Pan F, Chen Y, Jiang H, Sha BY, Recker RR, Deng HW. In vivo differential expression profiling study on human circulating B cells suggested a novel EGFR and CALM3 network underlying smoking and BMD. (The 30^th ASBMR Annual meeting, September 2008, #SU154)
• Xiao P, Chen XD, Pan F, Chen Y, Jiang H, Sha BY, Recker RR, Deng HW. In vivo differential expression profiling study on human circulating monocytes suggested a novel CRAT and CPT2 network underlying smoking and BMD. (The 30^th ASBMR Annual meeting, September 2008, #SU155)