University of Nebraska Medical Center

Jawed A. Siddiqui, PhD

Assistant Professor


Jawed A. Siddiqui

One of the major objectives of Dr. Siddiqui's laboratory is to elucidate biological mechanisms underlying bone metastasis of different malignancies. Bone metastases or dissemination of cancer cells within the bone are considered an advanced, debilitating, and incurable disease. Despite its high morbidity and mortality, the biology of bone metastasis signifies one of the most multifaceted and fascinating processes in several malignancies. Prostate, breast, lung, and kidney cancers have characteristics of selective bone tropism.

Research Interests

  1. Molecular mechanism of bone metastasis (Prostate, Breast, and Lung cancer)
  2. Bone Microenvironment and the vicious cycle of bone metastasis
  3. Osteoimmunology and Tumor Dormancy.
  4. Chemokine regulation of Metastasis
  5. Development of the Bone metastatic Therapeutics
  • PhD (Endocrinology, Bone Biology): Central Drug Research Institute (CDRI-JNU), India
Post-Doctoral Training
  • University of California, San Diego, CA
  • New York University, New York, NY
Research Opportunities

If you are excited about contributing to bone metastasis research, join our collaborative team. We always look for a highly enthusiastic researcher to join as graduate students, summer fellows, clinical fellows, and post-doctoral fellows. We are continuously open to collaboration.

Pipettes sit in a tray in a lab

Current Projects

Dr. Siddiqui's lab investigates bone metastasis, bone microenvironment, chemokines and cytokines, osteoimmunology, bone-muscle cross-talk, and cancer therapeutics.