Precision Prevention and Population Health

Program Overview

The Fred & Pamela Buffett Cancer Center (FPBCC) Cancer Prevention and Control (CPC) Program's mission is to identify key factors that contribute to preventable cancer risk and develop effective approaches to reduce the cancer burden and improve cancer survivorship outcomes in Nebraska and beyond.

The CPC research program includes members from the University of Nebraska System, who bring multidisciplinary expertise across 14 departments and eight colleges. They apply leading-edge research methods to confront the specific cancer challenges faced by people in Nebraska. 

Program Aims 

The Cancer Prevention & Control Program spans basic, clinical, and population science. It aims to find ways to lower cancer risk and improve outcomes for patients, families and communities in Nebraska. The program plays a vital role in advancing population health research while promoting multidisciplinary team science by strengthening both internal and external partnerships. 

Aim 1: Identify and Address Cancer Risk Drivers  
We investigate the behavioral, environmental, and social factors that contribute to cancer development and outcomes. Our team examines modifiable risk factors including tobacco use, obesity, environmental exposures, and social determinants of health. This research directly informs evidence-based interventions and policy recommendations. 

Aim 2: Advance Early Detection and Prevention  
Our investigators develop and validate novel screening methods for early cancer detection while creating innovative interventions to prevent cancer initiation and progression. From biomarker discovery to community-based screening programs, we're working to identify cancer at its earliest, most treatable stages and implement effective prevention strategies. 

Aim 3: Improve Cancer Survivor Outcomes  
We focus on enhancing quality of life and long-term health outcomes for cancer survivors through research in symptom management, treatment-related toxicity reduction, and survivorship care. Our work addresses critical issues including frailty, cognitive impairment, fertility preservation, and exercise interventions that help survivors thrive after treatment.