Precision Prevention and Population Health

Program Overview

The Fred & Pamela Buffett Cancer Center (FPBCC) Cancer Prevention and Control (CPC) research program focuses on identifying key factors that contribute to preventable cancer risk and developing effective approaches to reduce the cancer burden and improve cancer survivorship outcomes in Nebraska and beyond.  

The CPC research program brings together members with multidisciplinary expertise from 14 departments and eight colleges across the University of Nebraska System.  

Aims

The Cancer Prevention and Control program spans basic, clinical, and population science. It aims to find ways to lower cancer risk and improve outcomes for patients, families, and communities in Nebraska. The program plays a vital role in advancing population health research while promoting multidisciplinary team science by strengthening both internal and external partnerships.  

Aim 1: Identify and Address Cancer Risk Drivers   
Investigate behavioral, environmental, and social factors that contribute to cancer development and outcomes. Current interventions are based on research that examines modifiable risk factors, including tobacco use, obesity, environmental exposures, and social determinants of health.  

Aim 2: Advance Early Detection and Prevention   
The program's integrated biomarker and intervention research focuses on developing biomarkers, validating novel screening methods, and implementing community-based screening programs aimed at identifying cancer at its earliest, most treatable stages, while delivering effective prevention strategies.  

Aim 3: Improve Cancer Survivor Outcomes   
The program’s survivorship and palliative care research focuses on symptom management, reduction of treatment-related toxicities, and long-term survivorship care. Current studies address critical issues such as frailty, cognitive impairment, fertility preservation, and exercise interventions to help survivors thrive after treatment.