Mahesh Pattabiraman, Ph.D.
MaheshPattabiraman.jpg Mahesh Pattabiraman, Ph.D.
Associate Professor of organic chemistry
University of Nebraska at Kearney


Hometown: 
Chennai, India 

Year you joined the INBRE program: 2020 Fall 

Research focus? Cancer therapeutics and antinociceptives 

Goal of your research? The aim of my research is to identify ligands for adenosine receptors (ARs) that could potentially be useful in developing anti-cancer agents, especially for the treatment of prostate and breast cancer. My research is based on my ability to synthesize structural analogs of natural compounds that have medicinal properties, which serve as lead structures in my drug discovery effort.  

Your research will make a difference because? Adenosine receptors serve several functions in human physiology, and they are recognized to be significantly involved in cancer proliferation. Thus, the ability to control their activity through ligands that regulate their function could lead to the discovery of anti-cancer agents. ARs are also involved in pain mediation pathways in mammals and knowledge of AR ligands would be useful in this regard as well. 

Three things people may not know about you. 

  1. I am pretty decent in bench tap music.
  2. I am a very curious person.
  3. I am a political junkie.