Rakesh K. Singh, Ph.D. Receives R01 Grant
Current therapeutic strategies for pancreatic cancer are largely ineffective, and metastatic disease frequently develops even after potentially curative surgery. The specific objective of this project is to investigate whether CXCR2 and its ligands play a critical pro-tumorigenic role in Kras-dependent modulation of tumor cells and microenvironment during pathogenesis. This grant application will decipher the underlying mechanism(s) and will develop innovative cancer therapies targeting CXCR2 signaling in combination with conventional anti-tumor regimens is a very real possibility in pancreatic cancer.
Joint Effort for Drug Development Pipeline
A contract awarded by the Department of Defense’s Armed Forces Radiobiology Research Institute seeks assistance from the University of Nebraska to develop medical countermeasures for prevention and/or treatment of Acute Radiation Syndrome. The project, led in a joint effort by Drs. Ken Bayles (UNMC) and Dave Berkowitz (UNL), will activate a University-wide “Drug Development Pipeline”, which will coordinate the activities of a broad range of expertise in drug development across the University system. Initial phases of the project will involve a “concept refinement study” establishing a plan to identify promising lead compounds and then utilizing the Pipeline to carry out the studies needed for advancement to phase I clinical trials. Learn more at UNMC Today!
Dr. Cox invents in response to staff needs
Dr. Jesse Cox, current Chief Resident within our department, has developed a 3D-Printed Microscope Smartphone Mount. After hearing staff members were struggling using their iPhones to assist each other with a frozen section off campus, Dr. Cox designed a device to position a smartphone, quickly and easily, to an eyepiece to capture photos and video. While current available devices do exist to perform similar functions, most are cumbersome and/or expensive. Using 3D printing resources available on campus, multiple prototypes were developed, ultimately landing upon a design both universal and easy to use. As part of his experience, Dr. Cox spoke and worked with area high school students involved in club organizations through their high schools regarding the design, development and prototyping process through DoSpace and the UNMC Makers' Invent-a-thon Contest held in the spring. Dr. Cox launched Yellow Basement Design to sell his devices to a larger market.
Where Are They Now?
As Adjunct Faculty at Metro Community College, Dr. Scherr teaches Intro to Biology. In 2017, Dr. Scherr was awarded the McNair Alumni Appreciation Award from UNL.
Larson receives task order from NSRI
Marilynn Larson, Ph.D., has received a task order from the National Strategic Research Institute to develop and optimize microbial assays and provide training on their use as a diagnostic tool in the field.
Faculty and lab staff continue to publish
Drs. Kai Fu, Timothy Greiner, Ji Yuan and Chengfeng Bi along with lab staff have just published "Rac1 is a novel therapeutic target in mantle cell lymphoma" in Blood Cancer Journal.
Welcoming Dr. Cook to department
Welcoming Dr. Reid to department
Learning gap or generational gap
Our faculty participate in new E-Learning projects
Dr. Campbell creates new lexicon
Welcoming Dr. Ng to department